Carnegie stage 19
Embryology - 26 Apr 2024 Expand to Translate |
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Introduction
Facts
Week 7, 48 - 51 days, 16 - 18 mm
Gestational Age GA - week 9
Summary
- Ectoderm: sensory placodes, lens pit, otocyst, nasal pits moved ventrally, fourth ventricle of brain
- Mesoderm: heart prominence, ossification continues
- Head: forebrain, eye, external acoustic meatus
- Body: straightening of trunk, heart, liver, umbilical cord
See also Stage 19 Events
Features
- eyelid, eye, external acoustic meatus, auricle of external ear, digital ray, wrist, liver prominence
- Identify: straightening of trunk, pigmented eye, eyelid, external acoustic meatus, digital rays, liver prominance, thigh, ankle, foot plate, umbilical cord
- Links: Week 7 | System Development | Lecture - Limb | Lecture - Head Development | Lecture - Sensory | Science Practical - Head | Science Practical - Sensory | Science Practical - Urogenital | Category:Carnegie Stage 19 | Stage 20
Week: | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
Carnegie stage: | 1 2 3 4 | 5 6 | 7 8 9 | 10 11 12 13 | 14 15 | 16 17 | 18 19 | 20 21 22 23 |
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Bright Field
Virtual Slide
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- Facts: Week 7, 48 - 51 days, 16 - 18 mm
- View: Lateral view. Amniotic membrane removed.
- Features: eyelid, eye, external acoustic meatus, auricle of external ear, digital ray, wrist, liver prominence
- Identify: straightening of trunk, pigmented eye, eyelid, external acoustic meatus, digital rays, liver prominance, thigh, ankle, foot plate, umbilical cord
Image: Dr Steven O'Connor (Houston, Texas) - Other embryo images.
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Cite this page: Hill, M.A. (2024, April 26) Embryology Carnegie stage 19. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_19
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
Scanning EM
Ventral view of head showing upper lip, maxilla and nasal region.
Image Source: Prof Virginia Diewert
Kyoto Collection
View: This is a dorsolateral view of embryo. Amniotic membrane removed.
Image source: Embryology page Created: 19.03.1999
Image source: The Kyoto Collection images are reproduced with the permission of Prof. Kohei Shiota and Prof. Shigehito Yamada, Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan for educational purposes only and cannot be reproduced electronically or in writing without permission.
Carnegie Collection
- Carnegie stage 19: 4501 Right | 4501 Anterior | 4501 Left | 6824 Right | 6824 Anterior | 6824 Left | 8092 Right | 8092 Anterior | 8092 Left
Carnegie Collection - Stage 19 | |||||||||||
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Serial No. | Size (mm) | Grade | Fixative | Embedding Medium | Plane | Thinness (µm) | Stain | Score | Sex | Year | Notes |
17 | E, 18 Ch, 40x30x20 | Poor | Alc. | P | 50, 100 | Al. carm. | 16.5 | Male | 1894 | ||
43 | E, 16 | Good | Alc. | P | 50 | Al. coch. | 10 | Male | 1894 | ||
293 | E, 19 | Poor | Ale. | P | Sagittal | 50 | Coch. | 16.5 | S | 1905 | |
390 | E, 19 | Good | Formol? | P | Sagittal | 20, | (Stain - Haematoxylin Eosin) | 11.5 | Male | 1906 | Tubal Injected
50 |
409 | E.18 Ch, 50x40x40 | Good | Formalin | P | Transverse | 20 | Copper, iron H. & erythrosin | 14.5 | Male | 1907 | |
432 | E..18.5 Ch , 45x35x20 | Good | Formalin | P | Sagittal | 20 | H. & Congo red | 13.5 | Male | 1910 | Tubal |
576 | E. 17 Ch, 60x40 | Good | Formalin | P | Sagittal | 15, 20 | (Stain - Haematoxylin Eosin) | 14.5 | d | 1912 | Tubal |
626 | E., 21.5 Ch., 40x30x21 | Good | Formalin | P | Transverse | 100 | Al. coch. | 14_5 | 6 | 1913 | |
6??8 | E, 20 Ch, ca. 30 | Poor | Formalin | P | Sagittal | 50 | Al. coch. | 12 | 9 | 1913 | Head damaged |
709 | E, 19 Ch. 40x35x25 | Poor | Alc. | P | Coronal | 40 | Al. coch, Lyons blue | 15 | 49 | 1913 | |
837 | E. 21 Ch. 65x45x | Good | Formalin | P | Sagittal | 40 | Al. coch. | 14.5 | P | 1914 | |
1324 | E., 18 50x30x18 | Good | Formalin | C | Coronal | 40 | (Stain - Haematoxylin Eosin), aur, or. G | 125 | 79 | 1915 | |
1332 | E., 19 Ch., 40x43x22 | Poor | Formalin | C | Coronal | 40 | (Stain - Haematoxylin Eosin) aur, or. G. | 15 | Male | 1915 | |
1390 | E., 18 Ch, 40x38x15 | Good | Formalin | P | Sagittal | 20 | Al. coch. | 10_5 | Male | 1915 | Tubal |
1534 | E., 13 Ch.,35x31x25 | Poor | Formalin | P | 53% | 50 | Al. coch. | 13.5 | F | 1916 | Protruding midbrain |
2114 | E., 19.3 Ch., 49x42x33 | Good | Formol | P | Transverse | 40 | A1. coch. | 12 | M | 1918 | |
4405 | E., 15.5 | Good | Formalin | P | Transverse | 10 | Coch, Mallory | 13.5 | <3 | 1923 | Midbrain injured |
4501 | E, 18 | Exc. | Bouin | P | Transverse | 15 | Coch, or. G. | 14.6 | 1924 | Cystic left kidney | |
5609 | E., 18 | Exc. | Formalin | P | Coronal | 25 | A1. coch. | 13.5 | Male | ||
6150 | E., 17 Ch., 40x39x30 | Good | Bouin | C-P | Transverse | 15 | (Stain - Haematoxylin Eosin) | 16.5 | Male | 1930 | Tubal |
6824 | E., 18.5 Ch., 45x40x25 | Good | Formalin | C-P | Sagittal | 12 | (Stain - Haematoxylin Eosin) | 14.5 | Female | 1933 | |
7900 | E., 16.5 | Good | Bouin | C-P | Sagittal | 20 | (Stain - Haematoxylin Eosin), phlox. | 11.5 | . . | 1941 | Tubal |
8092 | E., 16.3 Ch., 52 x 47 | Exc. | Bouin | C-P | Transverse | 20 | (Stain - Haematoxylin Eosin), phlox. | 13 | Male | 1942 | |
8913 | E.,? Ch, 34 | Poor | Formalin | p | Transverse | 10 | Alan . | 7 | 1951 | rubella. Medical abortion. Isolated head damaged | |
8965 | E, 19.1 Ch, 42x32x19 | Good | Formol—Zenker | C-P | Transverse | 10 | Borax, carm, or. G. | 1952 | Univ. Chicago No. H 173 | ||
9097 | E, 21 | Exc. | Formol—glucose | C-P | Coronal | 10 | Azan ? . | ? | 1930 | Univ. Chicago No H 1380 | |
9113 | E, 185 Ch, 24 | Exc. | Formalin | C-P | Transverse | 10 | Alan > 6 | 1953 | Rubella. Medical abortion | ||
9325 | E, 17.0 Ch, 32x28x20 | Good | Formalin | —acetic p | Transverse | 15& 8-10 | Azan & Ag | ? | - | 1955 | Tubal |
Abbreviations
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iBook - Carnegie Embryos | |
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Blechschmidt Collection
Embryo (170452)
- Links: Blechschmidt Collection
Photographs
Virtual Slide | |
Image - Dr Ed Uthman | Image - Dr Steven O'Connor |
Embryo Virtual Slides
Stage 19 - Left Lateral |
Stage 19 | Embryo Slides |
Hill Collection
Righthand view | Lefthand view |
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Image source: The images from the Hill Collection (part of the Embryological Collection) are reproduced with the permission of the Museum für Naturkunde, Leibniz Institute for Research on Evolution and Biodiversity. Images are for educational purposes only and must not be reproduced electronically or in writing without permission from the Museum für Naturkunde Berlin.
Embryo Virtual Slides
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Hinrichsen Collection
Hinrichsen collection Human Embryo ME28 (stage19).
Embryo left lateral view. |
Image source: The Hinrichsen Collection images are reproduced with the permission of Prof. Beate Brand-Saberi, Head, Department of Anatomy and Molecular Embryology, Ruhr-Universität Bochum. Images are for educational purposes only and cannot be reproduced electronically or in writing without permission.
Events
- Vision - (stage 19 -22) the eyelid folds develop into the eyelids and cover more of the eye as the palpebral fissure takes shape. The upper and the lower eyelids meet at the outer canthus in Stage 19. [2]
- Hearing - otic capsule now cartilaginous. Cochlea tip becomes curled. Malleus and incus present.
- Cardiovascular
- Cerebral artery the middle cerebral artery becomes more prominent, the plexi fuse into a single artery and further branches pierce the cerebral hemisphere.[3]
- arterial system[4] Chapter 18 fig. 447).
- aortic arches [5] stages 11–19 (figs. 29–40).
- Heart fusion of aortic and mitral endocardial cushion material</ref>Teal SI., Moore GW. and Hutchins GM. Development of aortic and mitral valve continuity in the human embryonic heart. (1986) Amer. J. Anat., 176:447-460.</ref>
- Respiratory - first generation of subsegmental bronchi now complete, see bronchial tree reconstruction[6] (plates 3 and 4).
- Gastrointestinal - anal membrane defined.
- Renal - Cloacal membrane ruptures from urinary pressure at stage 18 or stage 19,
- Genital
- Musculoskeletal - Sternum right and left sternal bars are present.[9] (figs. 7-17 and 7-22)
- Neural
- rhombencephalon migration for olivary and arcuate nuclei begins.
- choroid plexus of the fourth ventricle present.
- stria medullaris thalami reaches the habenular nuclei.
- habenular commissure begins to develop.
References
- ↑ Streeter GL. Developmental Horizons In Human Embryos Description Or Age Groups XIX, XX, XXI, XXII, And XXIII, Being The Fifth Issue Of A Survey Of The Carnegie Collection. (1957) Carnegie Instn. Wash. Publ. 611, Contrib. Embryol., 36: 167-196.
- ↑ <pubmed>7364662</pubmed>
- ↑ <pubmed>26060802</pubmed>| J Stroke.
- ↑ Keibel F. and Mall FP. Manual of Human Embryology II. (1912) J. B. Lippincott Company, Philadelphia.
- ↑ Congdon ED. Transformation of the aortic-arch system during the development of the human embryo. (1922) Contrib. Embryol., Carnegie Inst. Wash. Publ 277, 14:47-110.
- ↑ Wells LJ. Development of the human diaphragm and pleural sacs. (1954) Contrib. Embryol., Carnegie Inst. Wash. Publ. 603, 35: 107-134.
- ↑ Jirásek JE. Development of the Genital System and Male Pseudohermaphroditism. (1971) Johns Hopkins Press, Baltimore.
- ↑ {{Ref-Wilson1926a))
- ↑ Gasser RL. Atlas of Human Embryos. (1975) Harper & Row, Hagerstown, Maryland.
Additional Images
Historic
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Pages where the terms "Historic" (textbooks, papers, people, recommendations) appear on this site, and sections within pages where this disclaimer appears, indicate that the content and scientific understanding are specific to the time of publication. This means that while some scientific descriptions are still accurate, the terminology and interpretation of the developmental mechanisms reflect the understanding at the time of original publication and those of the preceding periods, these terms, interpretations and recommendations may not reflect our current scientific understanding. (More? Embryology History | Historic Embryology Papers) |
1922 Embryo 18 mm reconstruction model, Carnegie Embryo 1390
1922 Carnegie Embryo 1390
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Cite this page: Hill, M.A. (2024, April 26) Embryology Carnegie stage 19. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_19
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G