Carnegie stage table
|Embryology - 27 Sep 2020 Expand to Translate|
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|contributors to the site. The good news is Embryology will remain online and I will continue my association with UNSW Australia. I look forward to updating and including the many exciting new discoveries in Embryology!|
Carnegie stages are named after the famous US Institute which began collecting and classifying embryos in the early 1900's. Stages are based on the external and/or internal morphological development of the embryo, and are not directly dependent on either age or size. The human embryonic period proper is divided into 23 Carnegie stages covering the first 8 weeks post-ovulation.
|Carnegie stage:||1 2 3 4||5 6||7 8 9||10 11 12 13||14 15||16 17||18 19||20 21 22 23|
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Carnegie Stage Table
Weeks shown in the table below are embryonic post ovulation age, for clinical Gestational Age (GA) measured from last menstrual period, add 2 weeks.
(not to scale)
|fertilized oocyte, zygote, pronuclei|
|morula cell division with reduction in cytoplasmic volume, blastocyst formation of inner and outer cell mass|
|loss of zona pellucida, free blastocyst|
|extraembryonic mesoderm, primitive streak, gastrulation|
|gastrulation, notochordal process|
|primitive pit, notochordal canal|
|Somitogenesis Somite Number 1 - 3 neural folds, cardiac primordium, head fold|
|Somite Number 4 - 12 neural fold fuses|
|Somite Number 13 - 20 rostral neuropore closes|
|Somite Number 21 - 29 caudal neuropore closes|
|Somite Number 30 leg buds, lens placode, pharyngeal arches|
|lens pit, optic cup|
|lens vesicle, nasal pit, hand plate|
|nasal pits moved ventrally, auricular hillocks, foot plate|
|straightening of trunk|
|upper limbs longer and bent at elbow|
|hands and feet turned inward|
|eyelids, external ears|
|rounded head, body and limbs|
Streeter GL. Developmental horizons in human embryos. Description of age group XI, 13 to 20 somites, and age group XII, 21 to 29 somites. (1942) Contrib. Embryol., Carnegie Inst. Wash. Publ. 541, 30: 211-245.
Streeter GL. Developmental horizons in human embryos. Description of age group XIII, embryos about 4 or 5 millimeters long, and age group XIV, period of indentation of the lens vesicle. (1945) Carnegie Instn. Wash. Publ. 557, Contrib. Embryol., Carnegie Inst. Wash., 31: 27-63.
Streeter GL. Developmental horizons in human embryos. Description of age groups XV, XVI, XVII, and XVIII, being the third issue of a survey of the Carnegie collection. (1948) Contrib. Embryol., Carnegie Inst. Wash. 575, 32: 133-203.
Streeter GL. Developmental horizons in human embryos. Age groups XI to XXIII. (1951) Carnegie Institution of Washington, Washington, D. C.
Streeter GL. Developmental Horizons In Human Embryos Description Or Age Groups XIX, XX, XXI, XXII, And XXIII, Being The Fifth Issue Of A Survey Of The Carnegie Collection. (1957) Carnegie Instn. Wash. Publ. 611, Contrib. Embryol., 36: 167-196.
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|Embryology History | Historic Embryology Papers)|
Keibel and Elze Normentafel (1908)
The following human growth data is from Mall (1910)
- Mall FP. VIII. Determination of the age of human embryos and fetuses in Keibel F. and Mall FP. Manual of Human Embryology I. (1910) J. B. Lippincott Company, Philadelphia.
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Cite this page: Hill, M.A. (2020, September 27) Embryology Carnegie stage table. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_table
- © Dr Mark Hill 2020, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G