Embryonic Development: Difference between revisions
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== Introduction == | == Introduction == | ||
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! Author Comments | ! Author Comments | ||
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| [[File:Mark_Hill.jpg|50px]] '''Start here''' by looking at the external appearance of embryos in sequence from [[#Carnegie_Stages|1 to 23]]. It is not so important to memorise the dates, as they are only approximate, but more important to understand '''growth''' (size changes) and the '''development''' (overall sequence of events) during this period. | | [[File:Mark_Hill.jpg|50px]] '''Start here''' by looking at the external appearance of embryos in sequence from [[#Carnegie_Stages|1 to 23]]. It is not so important to memorise the dates, as they are only approximate, but more important to understand '''growth''' (size changes) and the '''development''' (overall sequence of events) during this period. | ||
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! Carnegie Collection | ! Carnegie Collection | ||
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| [[File:Human Carnegie stage 1-23.jpg|550px]] | | [[File:Human Carnegie stage 1-23.jpg|alt=Kyoto Collection Embryos|link=Kyoto Collection|550px]] | ||
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| [[File:Human Carnegie stage 10-23.jpg|420px]] | | [[File:Human Carnegie stage 10-23.jpg|alt=Carnegie Collection Embryos|link=Carnegie Collection|420px]] | ||
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| Human Embryo, Carnegie stages 1-23 | | Human Embryo, Carnegie stages 1-23 | ||
Latest revision as of 06:46, 13 December 2018
| Embryology - 13 Aug 2026 |
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Introduction
| Author Comments |
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Clicking the Carnegie stage numbers opens a page dedicated to describing that single stage and the associated developmental events. |
| This page shows some key events of human development during the embryonic period of the first eight weeks (weeks 1 - 8) following fertilization. This period is also considered the organogenic period, when most organs within the embryo have begun to form.
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| Kyoto Collection | Carnegie Collection | |
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| Human Embryo, Carnegie stages 1-23 | Human Embryo, Carnegie stages 10-23 |
| <html5media height="530" width="375">File:Embryo stages 003.mp4</html5media> | Use the stage number links to images and information about each specific stage of human development over the first 8 weeks. The links below give a broad overview of developmental events during each week.
Embryo sizes - stage 14 compared to 23
Embryo Week: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9 |
Week 1
- Week 1 Carnegie stage - 1 | 2 | 3 | 4
- oocyte | spermatozoa | fertilization
- zygote
- morula
- blastocyst
| Week 1 Links: stage 1 | stage 2 | stage 3 | menstrual cycle | fertilization | zygote | morula | blastocyst | Lecture - Fertilization | meiosis | mitosis | Lecture - Week 1 and 2 | menstrual cycle | oocyte | spermatozoa | twinning | Genetic risk maternal age | Trisomy 21 | Trisomy 18 | Trisomy 13 | hydatidiform mole | GA week 3 |
| Carnegie stages | |||
|---|---|---|---|
| stage 1 | stage 2 | stage 3 | stage 4 |
Week 2
- Week 2 Carnegie stage - 5 | 6
- trophoblast - (trophectoderm) outer cell layer
- Embryoblast - inner cell mass
- implantation
- Bilaminar embryo
| Week 2 Links: stage 4 | stage 5 | stage 6 | Lecture - Week 1 and 2 | implantation | trophoblast | human chorionic gonadotropin | pregnancy test | twinning | Category:Week 2 | GA week 4 |
| Carnegie stages | ||
|---|---|---|
| stage 4 | stage 5 | stage 6 |
Week 3
| Week 3 Links: stage 7 | stage 8 | stage 9 | Gastrulation | Endoderm | Mesoderm | Ectoderm | Placenta | Coelomic Cavity | Lecture | Category:Week 3 | GA week 5 |
| Carnegie stages | ||
|---|---|---|
| stage 7 | stage 8 | stage 9 |
Week 4
| Week 4 Links: stage 10 | stage 11 | stage 12 | 13 | Placodes | Pharyngeal arches | Lecture - Mesoderm | Lecture - Ectoderm | Lecture - Early Vascular | Category:Week 4 | GA week 6 |
| Carnegie stages | |||
|---|---|---|---|
| stage 10 | stage 11 | stage 12 | stage 13 |
Week 5
| Carnegie stages | |
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| stage 14 | stage 15 |
Week 6
| Carnegie stages | |
|---|---|
| stage 16 | stage 17 |
Week 7
| Carnegie stages | |
|---|---|
| stage 18 | stage 19 |
Week 8
| Carnegie stages | |||
|---|---|---|---|
| stage 20 | stage 21 | stage 22 | stage 23 |
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Carnegie Stage Table
Weeks shown in the table below are embryonic post ovulation age, for clinical Gestational Age (GA) measured from last menstrual period, add 2 weeks.
(not to scale) |
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| fertilized oocyte, zygote, pronuclei | ||||
| morula cell division with reduction in cytoplasmic volume, blastocyst formation of inner and outer cell mass | ||||
| loss of zona pellucida, free blastocyst | ||||
| attaching blastocyst | ||||
(week 2) |
implantation | |||
| extraembryonic mesoderm, primitive streak, gastrulation | ||||
| gastrulation, notochordal process | ||||
| primitive pit, notochordal canal | ||||
| Somitogenesis Somite Number 1 - 3 neural folds, cardiac primordium, head fold | ||||
| Somite Number 4 - 12 neural fold fuses | ||||
| Somite Number 13 - 20 rostral neuropore closes | ||||
| Somite Number 21 - 29 caudal neuropore closes | ||||
| Somite Number 30 leg buds, lens placode, pharyngeal arches | ||||
| lens pit, optic cup | ||||
| lens vesicle, nasal pit, hand plate | ||||
| nasal pits moved ventrally, auricular hillocks, foot plate | ||||
| finger rays | ||||
| ossification commences | ||||
| straightening of trunk | ||||
| upper limbs longer and bent at elbow | ||||
| hands and feet turned inward | ||||
| eyelids, external ears | ||||
| rounded head, body and limbs | ||||
The embryos shown in the table are from the Kyoto and Carnegie collection and other sources.
References
- ↑ Findlay JK, Gear ML, Illingworth PJ, Junk SM, Kay G, Mackerras AH, Pope A, Rothenfluh HS & Wilton L. (2007). Human embryo: a biological definition. Hum. Reprod. , 22, 905-11. PMID: 17178746 DOI.
- ↑ O'Rahilly R. 1979. Early human development and the chief sources of information on staged human embryos. Europ. J. Obstet. Gynec. Reprod. Biol., 9, 273-280. PMID 400868
- ↑ O'Rahilly R. and Müller F. Developmental Stages in Human Embryos. Contrib. Embryol., Carnegie Inst. Wash. 637 (1987).
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2026, August 13) Embryology Embryonic Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Embryonic_Development
- © Dr Mark Hill 2026, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
