Difference between revisions of "Carnegie stage 1"

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[[File:Early_zygote.jpg|left]]
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{{Header}}
Facts: Week 1, size 0.1-0.15 mm
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==Introduction==
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{|
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| width=310 valign=top|[[File:Early_zygote_labelled.jpg|300px]]
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Human early zygote showing male and female pronuclei
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|
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The early human {{zygote}} where the male and female {{pronuclei}} (centre of image) have not yet combined to form the single zygote nucleus. These pronuclei are the nuclei from the {{spermatozoa}} (sperm) and {{oocyte}} (egg) and contain all the nuclear genetic material (chromosomes, DNA, genes).
  
Features: [[Z#zygote|zygote]], fertilized oocyte, [[P#pronuclei|pronuclei]], [[P#polar bodies|polar bodies]], [[Z#zona pellucida|zona pellucida]]
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Two of the egg's {{polar bodies}} (right, 3 o'clock position of image) are shown at the edge of the egg cytoplasm. These polar bodies contain the excess DNA from the meiotic divisions of the egg.
  
The early human zygote where the male and female pronuclei (centre of image) have not yet combined to form the single zygote nucleus. These pronuclei contain all the nuclear DNA (genes) and are the nuclei from the sperm and egg.
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The {{zona pellucida}} (edge of image) forms a specialised thick extracellular matrix layer around both the egg and the developing conceptus for the first week.
  
Two of the egg's polar bodies (right, 3 o'clock position of image) are shown at the edge of the egg cytoplasm. These polar bodies contain the excess DNA from the meiotic divisions of the egg.
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The {{mitochondria}} in the cytoplasm contain additional genes and in humans these mitochondrial genes are entirely derived from the mother (oocyte).
  
The zona pellucida (edge of image) forms a specialised thick extracellular matrix layer around both the egg and the developing conceptus for the first week.
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===Summary===
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* Week 1, size 0.1 - 0.15 mm
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* fertilized oocyte, {{zygote}}, {{pronuclei}}, {{polar bodies}}, {{zona pellucida}}
  
'''Links:''' [[2009_Lecture_2|Science Lecture - Cell Division and Fertilization]] | [[Zona pellucida|Zona pellucida]]
 
  
==Additional Images==
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See also [[#Events|Events]]
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|}
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<br>
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{{Carnegie stage 1 links}}
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{{Carnegie_stage_table_1}}
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{{Carnegie stages}}
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==Carnegie stage 1==
  
 
<gallery>
 
<gallery>
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File:Early_zygote.jpg|Early zygote
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File:Early_zygote_labelled.jpg|Early zygote labeled
 
File:Stage1 size with ruler.jpg|Stage 1 size with ruler
 
File:Stage1 size with ruler.jpg|Stage 1 size with ruler
File:Human_zygote_two_pronuclei_01.jpg|Human zygote two pronuclei<ref name="PMID20579351"><pubmed>20579351</pubmed>| [http://www.rbej.com/content/8/1/77 Reprod Biol Endocrinol.]</ref>
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File:Human_zygote_two_pronuclei_01.jpg|Human zygote two pronuclei PMID 20579351
File:Human_zygote_two_pronuclei_02.jpg|Human zygote two pronuclei<ref name="PMID20579351" />
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File:Human zygote two pronuclei 03.jpg|Human zygote two pronuclei PMID 20579351
File:Human-oocyte_to_blastocyst.jpg|Human oocyte to blastocyst<ref><pubmed>19924284</pubmed></ref>
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File:Human_zygote_two_pronuclei_02.jpg|Human zygote two pronuclei PMID 20579351
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File:Human zygote two pronuclei 22.jpg|Human zygote two pronuclei (labelled) PMID 20579351
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File:Human-oocyte_to_blastocyst.jpg|Human oocyte to blastocyst PMID 19924284
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File:Human_fertilization_movie_1_frame_05.jpg|Human pronuclei
 
</gallery>
 
</gallery>
  
==References==
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===Electron Micrographs===
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<gallery>
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File:Human pronuclear stage EM02.jpg|Human pronuclei EM PMID 6008199
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File:Human pronuclear stage EM022.jpg|Human pronuclei EM PMID 6008199
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File:Human pronuclear stage EM03-05.jpg|Mitochondria
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File:Human pronuclear stage EM06.jpg|Human pronuclei
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File:Human pronuclear stage EM07.jpg|Human pronuclei
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File:Human pronuclear stage EM08.jpg|Human pronuclei
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File:Human pronuclear stage EM09.jpg|Human pronuclei
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File:Human pronuclear stage EM10.jpg|Human pronuclei
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File:Human pronuclear stage EM11.jpg|Human pronuclei
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File:Human pronuclear stage EM12.jpg|Human pronuclei
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File:Human pronuclear stage EM13.jpg|Human pronuclei
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File:Human pronuclear stage EM14-16.jpg|Human pronuclei
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File:Human pronuclear stage EM17.jpg|Human pronuclei
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File:Human pronuclear stage EM18.jpg|Human pronuclei
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File:Human pronuclear stage EM19.jpg|Human pronuclei
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File:Human pronuclear stage EM20.jpg|Human pronuclei
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File:Human pronuclear stage EM21.jpg|Human pronuclei
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File:Human pronuclear stage EM22.jpg|Spermatozoon Components
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File:Human pronuclear stage EM25.jpg|Golgi complex
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File:Human pronuclear stage EM26.jpg|First Polar Body
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File:Human pronuclear stage EM27.jpg|First Polar Body
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File:Human pronuclear stage EM28.jpg|First Polar Body
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File:Human pronuclear stage EM29.jpg|Second Polar Body
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File:Human pronuclear stage EM30.jpg|Second Polar Body
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</gallery>
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==Movies==
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{|
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| valign="bottom"|{{Human fertilization movie 1}}
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| valign="bottom"|{{Human fertilization movie 2}}
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|}
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==Other Species==
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<gallery>
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File:Mouse pronuclei 02.jpg|Mouse
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File:Mouse_zygote_pronuclei_01.jpg|Mouse
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</gallery>
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==Events==
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{{fertilisation}}
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{{meiosis}}
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{{mitosis}}
  
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===References===
 
<references/>
 
<references/>
  
{{Template:Carnegie_stages}}
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{{Ref-Zamboni1966}}
{{Template:Footer}}
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==Additional Images==
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===Historic Images===
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<gallery>
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File:Bailey015.jpg|Fig. 15. Diagram of fertilization of the ovum
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File:Bailey016.jpg|Fig. 16. Fertilization of the eggs of the star-fish and sea-urchin
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</gallery>
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{{Carnegie_stages}}
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{{Footer}}
  
[[Category:Human Embryo]] [[Category:Carnegie Stage]] [[Category:Carnegie Stage 1]] [[Category:Week 1]]
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[[Category:Zygote]][[Category:Human Embryo]] [[Category:Carnegie Stage]] [[Category:Carnegie Stage 1]] [[Category:Week 1]]

Latest revision as of 09:09, 14 May 2020

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A personal message from Dr Mark Hill (May 2020)  
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I have decided to take early retirement in September 2020. During the many years online I have received wonderful feedback from many readers, researchers and students interested in human embryology. I especially thank my research collaborators and contributors to the site. The good news is Embryology will remain online and I will continue my association with UNSW Australia. I look forward to updating and including the many exciting new discoveries in Embryology!

Introduction

Early zygote labelled.jpg

Human early zygote showing male and female pronuclei

The early human zygote where the male and female pronuclei (centre of image) have not yet combined to form the single zygote nucleus. These pronuclei are the nuclei from the spermatozoa (sperm) and oocyte (egg) and contain all the nuclear genetic material (chromosomes, DNA, genes).

Two of the egg's polar bodies (right, 3 o'clock position of image) are shown at the edge of the egg cytoplasm. These polar bodies contain the excess DNA from the meiotic divisions of the egg.

The zona pellucida (edge of image) forms a specialised thick extracellular matrix layer around both the egg and the developing conceptus for the first week.

The mitochondria in the cytoplasm contain additional genes and in humans these mitochondrial genes are entirely derived from the mother (oocyte).

Summary


See also Events


Stage 1 Links: Zygote | Week 1 | Oocyte | Spermatozoa | Zona pellucida | Mitosis | Genetics | Human Genome | Mitochondrial Genome | Lecture | Medicine Practical | Science Practical | Stage 2
Historic Papers  
1919 Human Ovum | 1944 Ova Maturation | 1944 In vitro fertilization | 1949 Early Ova | 1966 Pronuclear Stage | 1986 human oocytes in vitro
Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline

Carnegie stage 1

Electron Micrographs

Movies

Human fertilization 1 icon.jpg
 ‎‎Fertilisation to
4 Blastomere
Page | Play
Human fertilization 2 icon.jpg
 ‎‎Fertilization
Page | Play

Other Species

Events

fertilisation

meiosis

mitosis

References


Zamboni L. Mishell DR. Jr. Bell JH. snd Baca M. Fine structure of the human ovum in the pronuclear stage. (1966) J. Cell Biol, 30: 579-600. PMID 6008199

Additional Images

Historic Images



Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline



Cite this page: Hill, M.A. (2020, July 3) Embryology Carnegie stage 1. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_1

What Links Here?
© Dr Mark Hill 2020, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G