Carnegie stage 1

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Introduction

Early zygote labelled.jpg

Human early zygote showing male and female pronuclei

The early human zygote where the male and female pronuclei (centre of image) have not yet combined to form the single zygote nucleus. These pronuclei are the nuclei from the spermatozoa (sperm) and oocyte (egg) and contain all the nuclear genetic material (chromosomes, DNA, genes).

Two of the egg's polar bodies (right, 3 o'clock position of image) are shown at the edge of the egg cytoplasm. These polar bodies contain the excess DNA from the meiotic divisions of the egg.

The zona pellucida (edge of image) forms a specialised thick extracellular matrix layer around both the egg and the developing conceptus for the first week.

Mitochondria in the cytoplasm contain additional genes and in humans these mitochondrial genes are entirely derived from the oocyte.

Summary


See also Events


Stage 1 Links: Zygote | Week 1 | Oocyte | Spermatozoa | Zona pellucida | Mitosis | Genetics | Human Genome | Mitochondrial Genome | Lecture | Medicine Practical | Science Practical | Stage 2
Historic Papers  
1919 Human Ovum | 1944 Ova Maturation | 1944 In vitro fertilization | 1949 Early Ova | 1966 Pronuclear Stage | 1986 human oocytes in vitro
Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23
Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline

Carnegie stage 1

Electron Micrographs

Movies

Human fertilization 1 icon.jpg
 ‎‎Fertilisation to
4 Blastomere
Page | Play
Human fertilization 2 icon.jpg
 ‎‎Fertilization
Page | Play

Other Species

Events


References

Zamboni L, Mishell DR Jr, Bell JH, Baca M. Fine structure of the human ovum in the pronuclear stage. (1966) J. Cell Biol, 30: 579-600. PMID 6008199

Additional Images

Historic Images



Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline



Cite this page: Hill, M.A. 2017 Embryology Carnegie stage 1. Retrieved September 24, 2017, from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_1

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© Dr Mark Hill 2017, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G