BGDA Practical 12 - Embryo to Fetus: Difference between revisions
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Revision as of 12:37, 29 May 2017
Practical 12: Embryo to Fetus | Second Trimester | Third Trimester | Birth | Neonatal | Abnormalities |
Introduction
Identify the development and form of the week 8 embryo (Stage 22 and 23). This 3D reconstruction animations showing specific systems and the histological sections from which these were prepared. There are also virtual slides and selected cross-sections showing specific features.
Then look at the week 10 early fetus and observe developmental changes. The selected mid-sagittal section shows the overall fetal anatomy and the gallery of excerpts have further detailed descriptions of these regions.
Week 8 - Stage 22
stage 22, Week 8, 54 - 56 days, 23 - 28 mm
Mesoderm: heart prominence, ossification continues Head: nose, eye, external acoustic meatus Body:straightening of trunk, heart, liver, umbilicus: placental cord, midgut herniation, allantois, vitelline duct Limb: upper limbs longer and bent at elbow, foot plate with webbed digits, wrist, hand plate with separated digits Straightening of trunk, pigmented eye, eyelid, nose, external acoustic meatus, ear auricle, scalp vascular plexus, separated digits (fingers), thigh, ankle, umbilical cord |
Embryo Anatomy
Now examine selected regions of the Stage 22 embryo and their overall development in the 3D animations.
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Virtual Slides
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Week 8 - Stage 23
Week 8, 56 - 60 days, 27 - 31 mm
scalp vascular plexus, eylid, eye, nose, auricle of external ear, mouth, sholder, arm, elbow, wrist, toes separated, sole of foot, umbilical cord Mesoderm: ossification continues Head: eyelids, external ears, rounded head Body: straightening of trunk, intestines herniated at umbilicus Limbs: hands and feet turned inward |
Carnegie Stage 23 MRI movies | |||||||||||||||||||||||||||
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Oral Cavity
Cortex
Week 8 Developing Cortex |
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Human embryo, Week 8, (GA week 10) Carnegie stage 22 section from the neural tube at the level of the developing cortex. Inset (upper right) shows whole section overview and approximate level of section (red line). Grey box shows detailed image region of developing cerebrum layer thicknesses are shown in microns.
Developing Cortex will form from the thin outer layer called the cortical plate. The underlying layers transient structures that continue to supply cells to the cortex through fetal period, most of these layers will eventually be lost, except for a thin ventricular layer. Cells migrate out along radial glia that establish the initial columnar and layered structure of the cortex. Layers are named according to the nervous system revised terminology (1970)[1] Developing Vascular blood vessels can also be seen spanning the developing layers. In the adult, these vessels will be lined with non-fenestrated endothelial cells that together with other vascular cells (pericytes and vascular smooth muscle cells), glial cells (astrocytes and microglia) and neurons will form the "blood-brain barrier". Developing Ventricular Space is cerebrospinal fluid (CSF) filled and the lateral ventricles form within the cortical region. The inset image shows lying within the lateral ventricles, the choroid plexus the modified vascular structure that forms and secretes the CSF. Developing Meninges layers lie outside the neural tube. The thin pia mater that closely covers the entire brain. The mesh-like arachnoid mater and the sub-arachnoid space that will also be CSF filled. The dense dura mater lies outside these 2 layers and under the skull, it cannot be seen in the enlarged image. |
Spinal Cord
Week 8 Developing Spinal Cord (virtual slide) | |||||
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These listed features link to zoomed views of the virtual slide with the named feature generally in the centre of the view.
Use the (-) at the top left of the screen to see where this feature is located. | ||||
Spinal Cord Features | Other Features
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Week 10 - Fetus (40mm)
There are 4 sections taken in the sagittal plane (moving from the right at Plane A towards the midline at Plane D). Click on the small images (or the text below) to open the linked large image pages.
Adrenal
<html5media height="500" width="560">File:Adrenal medulla.mp4</html5media> | Cartoon shows example of some neural crest medial migration during week 4 and 5 and the structures formed at the level of the body.
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Human Embryo (8 weeks, stage 22) adrenal gland showing the fetal and permanent adrenal cortex. Note that the medulla of the adrenal gland is not yet encapsulated by the cortex. 8-9 weeks post conception (wpc) adrenal cortex synthesizes cortisol under the regulation of ACTH (also stimulates androstenedione and testosterone secretion). | Human Fetus (10 week, 40mm, parasagittal section) shows location of the developing adrenal gland. The spongy appearance at the centre of the adrenal is the degenerating fetal cortex. The dense region around the outside of the adrenal is the developing adult cortex.) |
Related Images
Fetus (week 10) Planes A (most lateral), B (lateral), C (medial) and D (midline) from lateral towards the midline.
- Human Fetus - most lateral | lateral | medial | midline
- Head - most lateral | lateral | medial | midline
- Cerebellum - most lateral | lateral | medial | midline
- Urogenital Unlabelled - most lateral | lateral | medial | midline
- Urogenital Labelled - most lateral | lateral | medial | midline
- Large Images - midline
- Image Source: UNSW Embryology, no reproduction without permission.
Practical 12: Embryo to Fetus | Second Trimester | Third Trimester | Birth | Neonatal | Abnormalities |
Additional Information
Links: Fetal Development - 10 Weeks | Stage 22 embryo slices
BGDA: Lecture 1 | Lecture 2 | Practical 3 | Practical 6 | Practical 12 | Lecture Neural | Practical 14 | Histology Support - Female | Male | Tutorial
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 26) Embryology BGDA Practical 12 - Embryo to Fetus. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/BGDA_Practical_12_-_Embryo_to_Fetus
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
- ↑ <pubmed>5414696</pubmed>