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Adrenal Medulla Development
This animation shows the dual embryonic origins of the adrenal development.
- neural crest origin, migrate adjacent to coelomic cavity, initially uncapsulated and not surrounded by fetal cortex, cells have neuron-like morphology
- 2 cell types - secrete epinepherine (adrenaline) 80%; secrete norepinepherine (noradrenaline) 20%
- mesothelium origin, epithelium lining the body cavity at the site of adrenal development
- Late Fetal Period - differentiates to form cortical zones
- Birth - zona glomerulosa, zona fasiculata present
- Year 3 - zona reticularis present
Neural crest cells migrate toward the coelomic cavity wall and form the adrenal medulla. These chromaffin (chromaphil) cells originally named because of their staining (yellow) with chromium salts.
Week 4 celomic epithelium (mesothelium) cells proliferate initially forming small buds that separate from the epithelium.
Week 6 these now mesenchymal cells first form the fetal adrenal cortex which will be later replaced by the adult cortex.
- Links: MP4 version | Endocrine - Adrenal Development | Endocrine Lecture
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Cite this page: Hill, M.A. (2023, December 10) Embryology Adrenal Medulla Development Movie. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Adrenal_Medulla_Development_Movie
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- © Dr Mark Hill 2023, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G