Abnormal Development - Toxoplasmosis: Difference between revisions
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The causal agent of Toxoplasmosis is the protist ''Toxoplasma gondii'' (T. gondii). This unicellular eukaryote is a member of the phylum Apicomplexa which includes other parasites responsible for a variety of diseases (malaria, cryptosporidiosis). The diagnosis and timing of an infection are diagnostically based on serological tests. | The causal agent of Toxoplasmosis is the protist ''Toxoplasma gondii'' (T. gondii). This unicellular eukaryote is a member of the phylum Apicomplexa which includes other parasites responsible for a variety of diseases (malaria, cryptosporidiosis). The diagnosis and timing of an infection are diagnostically based on serological tests. | ||
During a period of acute maternal infection, transplacental transmission can occur, and the rate of congenital toxoplasmosis with risk for severe fetal varies from 15 to 68%, depending on gestational age and the transmission rate is highest in the later stages of pregnancy. The congenital disease is characterized by a wide range of clinical manifestations (neurological, ophthalmological, and systemic involvement). Every 3 years experts from many areas meet at the "International Congress on Congenital Toxoplasmosis". | During a period of acute maternal infection, transplacental transmission can occur, and the rate of congenital toxoplasmosis with risk for severe fetal varies from 15 to 68%, depending on gestational age and the transmission rate is highest in the later stages of pregnancy. The congenital disease is characterized by a wide range of clinical manifestations (neurological, ophthalmological, and systemic involvement). Every 3 years, last held in 2010 Marseille France, experts from many areas meet at the "International Congress on Congenital Toxoplasmosis". | ||
A recent survey identified a low infection knowledge among doctors and nurses providing prenatal care in an endemic region.<ref name="PMID21747644"><pubmed>21747644</pubmed></ref> | A recent survey identified a low infection knowledge among doctors and nurses providing prenatal care in an endemic region.<ref name="PMID21747644"><pubmed>21747644</pubmed></ref> |
Revision as of 16:26, 25 July 2011
Introduction
The causal agent of Toxoplasmosis is the protist Toxoplasma gondii (T. gondii). This unicellular eukaryote is a member of the phylum Apicomplexa which includes other parasites responsible for a variety of diseases (malaria, cryptosporidiosis). The diagnosis and timing of an infection are diagnostically based on serological tests.
During a period of acute maternal infection, transplacental transmission can occur, and the rate of congenital toxoplasmosis with risk for severe fetal varies from 15 to 68%, depending on gestational age and the transmission rate is highest in the later stages of pregnancy. The congenital disease is characterized by a wide range of clinical manifestations (neurological, ophthalmological, and systemic involvement). Every 3 years, last held in 2010 Marseille France, experts from many areas meet at the "International Congress on Congenital Toxoplasmosis".
A recent survey identified a low infection knowledge among doctors and nurses providing prenatal care in an endemic region.[1]
Recent findings suggest that pre-pregnancy immunization against toxoplasmosis may not protect against reinfection by atypical strains.
Some Recent Findings
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Toxoplasmosis Lifecycle
Toxoplasma Tachyzoites
Ocular Toxoplasmosis
Clinical episodes of ocular toxoplasmosis can represent either acquire toxoplasmosis after birth or a reactivation of an infection that was acquired in utero.
Ocular toxoplasmosis is the commonest identifiable cause of posterior uveitis.
- Links: PubMed Health - Uveitis
References
Reviews
<pubmed>18624630</pubmed> <pubmed>15194258</pubmed> <pubmed>12776962</pubmed> <pubmed>12150751</pubmed>
Articles
<pubmed>21747644</pubmed>
Search Pubmed
Search Pubmed: Toxoplasmosis | Maternal Toxoplasmosis
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- NIH PubMed Health Toxoplasmosis
- ABC Radio The Health Report - Toxoplasmosis Broadcast Monday 30 April 2001
- Queensland Health Topic - Toxoplasmosis
- Cat World toxoplasmosis in cats
Glossary Links
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Cite this page: Hill, M.A. (2024, May 21) Embryology Abnormal Development - Toxoplasmosis. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Toxoplasmosis
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G