Week 5

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Key Events of Human Development during the fifth week (week 5) following fertilization or clinical gestational age GA week 7 (LMP).

Carnegie Stages: 14 | 15


Week 5 Links: stage 14 | stage 15 | Placodes | Pharyngeal arches | Lecture - Head | Atrial Ventricular Septation | Category:Week 5 | GA week 7
Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23

Timeline

Week 5 - Human Embryo Stages and Events (GA week 7) 
Embryo Week: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9
Day
Stage
Event
29
Pituitary - Week 5 elongation, contacts infundibulum, diverticulum of diencephalon

Heart - Week 5 septation starts, atrial and ventricular

Respire - Week 5 left and right lung buds push into the pericardioperitoneal canals (primordia of pleural cavity)

Respire - Week 5 to 17 lung histology - pseudoglandular

Hearing - Week 5 cochlear part of otic vesicle elongates (humans 2.5 turns)

30
   
31
   
32
Stage 14
Stage14 bf1c.jpg
Ectoderm - sensory placodes, lens pit, otocyst, nasal placode, primary/secondary vesicles, fourth ventricle of brain

Mesoderm - continued segmentation of paraxial mesoderm (somite pairs), heart prominence

Head - 1st, 2nd and 3rd pharyngeal arch, forebrain, site of lens placode, site of otic placode, stomodeum

Body - heart, liver, umbilical cord, mesonephric ridge visible externally as bulges.

Limb - upper and lower limb buds growing

Neural - first appearance of the future cerebral hemispheres. Cerebellar plate differentiated to an intermediate layer, and future rhombic lip identifiable[1]

Liver hepatic gland and its vascular channels enlarge, hematopoietic function appears[2]

33
Stage 15
Stage15 bf1.jpg

Neural - cranial nerves (except olfactory and optic) are identifiable in more advanced embryos[3]

34
 
35
  Eye - 35 to 37 days retinal pigment present
Note - the day timing of stages is only approximate, system names link to first page of that specific system, and events are based upon the literature cited below.
References
  1. F Müller, R O'Rahilly The first appearance of the future cerebral hemispheres in the human embryo at stage 14. Anat. Embryol.: 1988, 177(6);495-511 PubMed 3377191
  2. G Godlewski, R Gaubert-Cristol, S Rouy, M Prudhomme Liver development in the rat and in man during the embryonic period (Carnegie stages 11-23). Microsc. Res. Tech.: 1997, 39(4);314-27 PubMed 9407542
  3. F Müller, R O'Rahilly The development of the human brain, including the longitudinal zoning in the diencephalon at stage 15. Anat. Embryol.: 1988, 179(1);55-71 PubMed 3213956
Day
Stage
Event
29
Pituitary - Week 5 elongation, contacts infundibulum, diverticulum of diencephalon

Heart - Week 5 septation starts, atrial and ventricular

Respire - Week 5 left and right lung buds push into the pericardioperitoneal canals (primordia of pleural cavity)

Respire - Week 5 to 17 lung histology - pseudoglandular

Hearing - Week 5 cochlear part of otic vesicle elongates (humans 2.5 turns)

30
   
31
   
32
Stage 14 Stage14 bf1c.jpg Ectoderm - sensory placodes, lens pit, otocyst, nasal placode, primary/secondary vesicles, fourth ventricle of brain

Mesoderm - continued segmentation of paraxial mesoderm (somite pairs), heart prominence

Head - 1st, 2nd and 3rd pharyngeal arch, forebrain, site of lens placode, site of otic placode, stomodeum

Body - heart, liver, umbilical cord, mesonephric ridge visible externally as bulges.

Limb - upper and lower limb buds growing

Neural - first appearance of the future cerebral hemispheres. Cerebellar plate differentiated to an intermediate layer, and future rhombic lip identifiable[1]

Liver hepatic gland and its vascular channels enlarge, hematopoietic function appears[2]

33
Stage 15 Stage15 bf1.jpg

Neural - cranial nerves (except olfactory and optic) are identifiable in more advanced embryos[3]

34
 
35
  Eye - 35 to 37 days retinal pigment present

References

  1. F Müller, R O'Rahilly The first appearance of the future cerebral hemispheres in the human embryo at stage 14. Anat. Embryol.: 1988, 177(6);495-511 PubMed 3377191
  2. G Godlewski, R Gaubert-Cristol, S Rouy, M Prudhomme Liver development in the rat and in man during the embryonic period (Carnegie stages 11-23). Microsc. Res. Tech.: 1997, 39(4);314-27 PubMed 9407542
  3. F Müller, R O'Rahilly The development of the human brain, including the longitudinal zoning in the diencephalon at stage 15. Anat. Embryol.: 1988, 179(1);55-71 PubMed 3213956



Embryo Week: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9


Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline


Glossary Links

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols



Cite this page: Hill, M.A. 2017 Embryology Week 5. Retrieved June 26, 2017, from https://embryology.med.unsw.edu.au/embryology/index.php/Week_5

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© Dr Mark Hill 2017, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G