Carnegie stage 3: Difference between revisions
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[[File:Human embryo day 5 label.jpg]] [[File:Human embryo day 5.jpg|Stage 3 Day 5]] | {{Header}} | ||
==Introduction== | |||
{| | |||
| width=405px|[[File:Human embryo day 5 label2.jpg|400px]] | |||
Human blastocyst (day 5) still within zone pellucida. | |||
| valign="top"|The free-floating blastocyst has reached the uterine body still enclosed in the zone pellucida and "hatches" from this surrounding extracellular matrix. | |||
It is only after hatching that the blastocyst can attach to and then implant into the uterine wall. | |||
===Summary=== | |||
* Week 1, 4 - 5 days, size 0.1 - 0.2 mm | |||
* {{zona pellucida}}, {{trophoblast}} (trophectoderm) shell, [[I#inner cell mass|inner cell mass]], [[B#blastoceol|blastoceol]] | |||
See also [[#Events|Events]] | |||
{{Carnegie stage 3 links}} | |||
<br> | |||
{{Carnegie_stage_table_1}} | |||
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| [[File:Human embryo day 5 label.jpg|400px]] | |||
| [[File:Human embryo day 5.jpg|Stage 3 Day 5]] | |||
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{{Carnegie stages}} | |||
==Blastocyst Hatching== | |||
{| | {| | ||
| [[Image:CSt3.jpg]] | | [[Image:CSt3.jpg]] | ||
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Blastocyst is too the right of image and zona pellucida is shown to the left of the image. | Blastocyst is too the right of image and zona pellucida is shown to the left of the image. | ||
* small opening in the zona pellucida through which the blastocyst is hatching. | |||
* flattened trophoblast cells forming the outer cell layer of the blastocyst. | |||
* inner cell mass shown in the centre of the image and on the left-hand wall of the blastocyst. | |||
* blastocoel forming a large fluid-filled space within the blastocyst. | |||
|} | |||
{{Human blastocyst movie 4}} | |||
==Histiotrophic Nutrition== | |||
Term used to describe in early placenta development the intital transfer of nutrition from maternal to embryo (histiotrophic nutrition) compared to later blood-borne nutrition (hemotrophic nutrition). Histotroph is the nutritional material accumulated in spaces between the maternal and fetal tissues, derived from the maternal endometrium and the uterine glands. This nutritional material is absorbed by phagocytosis initially by blastocyst trophectoderm and then by trophoblast of the placenta. in later placental development nutrition is by the exchange of blood-borne materials between the maternal and fetal circulations, hemotrophic nutrition. | |||
===Reference=== | |||
{{#pmid:12050279}} | |||
==Carnegie Collection== | ==Carnegie Collection== | ||
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| [[File:Stage3 bf02.jpg|400px]] | | [[File:Stage3 bf02.jpg|400px]] | ||
|- | |- | ||
| 58 cell blastocyst (day 4) | | 58 cell blastocyst (day 4) (No. {{CE8794}}) | ||
| 107 cell blastocyst (day 4.5) | | 107 cell blastocyst (day 4.5) (No. {{CE8663}}) | ||
|} | |} | ||
{{Carnegie Collection stage 3 table}} | |||
<br> | |||
{{Carnegie Embryo iBook table}} | |||
==Events== | |||
* '''{{mitosis}}''' - blastomere cells divide by mitosis, without growth between divisions. initially at the same time (synchronous) but with each round at slightly different times (asynchronous) | |||
* '''{{blastocyst}}''' - a fluid-filled cavity develops within the cell mass. | |||
===References=== | |||
<references/> | |||
{{Ref-Hertig1956}} | |||
==Additional Images== | |||
{{Carnegie_stages}} | |||
{{ | {{Footer}} | ||
[[Category:Human Embryo]] [[Category:Carnegie Stage]] [[Category:Carnegie Stage 3]] [[Category:Week 1]] [[Category:Blastocyst]] | [[Category:Human Embryo]] [[Category:Carnegie Stage]] [[Category:Carnegie Stage 3]] [[Category:Week 1]] [[Category:Blastocyst]] | ||
[[Category:Carnegie Embryo 8794]][[Category:Carnegie Embryo 8663]] |
Latest revision as of 10:29, 9 January 2020
Embryology - 27 Jun 2024 Expand to Translate |
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Introduction
Human blastocyst (day 5) still within zone pellucida. |
The free-floating blastocyst has reached the uterine body still enclosed in the zone pellucida and "hatches" from this surrounding extracellular matrix.
It is only after hatching that the blastocyst can attach to and then implant into the uterine wall. Summary
See also Events
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- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Blastocyst Hatching
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Histiotrophic Nutrition
Term used to describe in early placenta development the intital transfer of nutrition from maternal to embryo (histiotrophic nutrition) compared to later blood-borne nutrition (hemotrophic nutrition). Histotroph is the nutritional material accumulated in spaces between the maternal and fetal tissues, derived from the maternal endometrium and the uterine glands. This nutritional material is absorbed by phagocytosis initially by blastocyst trophectoderm and then by trophoblast of the placenta. in later placental development nutrition is by the exchange of blood-borne materials between the maternal and fetal circulations, hemotrophic nutrition.
Reference
Burton GJ, Watson AL, Hempstock J, Skepper JN & Jauniaux E. (2002). Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy. J. Clin. Endocrinol. Metab. , 87, 2954-9. PMID: 12050279 DOI.
Carnegie Collection
58 cell blastocyst (day 4) (No. 8794) | 107 cell blastocyst (day 4.5) (No. 8663) |
Carnegie Collection - Stage 3 | |||||||||
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Serial No. | Normality | No. of Blastomeres | Size of Fixed Specimen (µm) | Fixative | Embedding Medium | Thinness (µm) | Stain | Year | Notes |
8663 | normal | 107 | 103x80 | Alc. & Bouin | C-P | 6 | (Stain - Haematoxylin Eosin) | 1949 | Hertig etal.(1954)[1] |
8794 | normal | 58 | 108x86 | Alc. & Bouin | C-P | 6 | (Stain - Haematoxylin Eosin) | 1950 | Hertig etal.(1954)[1] |
Abbreviations
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iBook - Carnegie Embryos | |
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Events
- mitosis - blastomere cells divide by mitosis, without growth between divisions. initially at the same time (synchronous) but with each round at slightly different times (asynchronous)
- blastocyst - a fluid-filled cavity develops within the cell mass.
References
- ↑ 1.0 1.1 Hertig AT. Rock J. Adams EC. and Mulligan W.J. On the preimplantation stages of the human ovum: a description of four normal and four abnormal specimens ranging from the second to the fifth day of development. (1954) Carnegie Instn. Wash. Publ. 603, Contrib. Embryol., 35: 199-220.
Hertig AT. Rock J. and Adams EC. A description of 34 human ova within the first 17 days of development. (1956) Amer. J Anat., 98:435-493.
Additional Images
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Cite this page: Hill, M.A. (2024, June 27) Embryology Carnegie stage 3. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_3
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G