Placenta - Histology
Embryology - 2 Dec 2023 ![]() ![]() ![]() |
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Introduction
This page introduces the histology of the placenta, the placental cord and fetal membranes.
Various developmental stages of the placental villi are shown including maternal decidua.
There are images of placental cord and the placental vessels (vein and arteries).
Histology Links: stains | fixatives | artifacts | menstrual histology | placenta histology | heart histology | liver histology | Pancreas | Gall Bladder | Colon | Renal | Respiratory Histology | Bone | Category:Histology | UNSW Histology |
Historic Histology Textbooks: 1941 Histology] | 1944 Oral Histology |
Hofbauer Cells

Hofbauer (1903) identified a sub-population of cells in the placenta that could be identified by specific histological stains, the finding he published 2 years later in 1905.[2] The cells have subsequently been named Hofbauer cells, see also the historic 1918 paper by Meyer.[3]
- human villous macrophages
- highly vacuolated cells
- located the core of placental villi and cord
- macrophages with micropinocytotic activity and phagocytosis ability
- possible paracrine role for early stages of placental vasculogenesis
Search PubMed" Hofbauer cells
- Historic Links: 1918 plasma cells of Hofbauer | 1921 Early descriptions of Hofbauer cells
Villi Histology
- Villi Histology: First trimester (overview | villi | detail) | fetal and maternal RBCs | Term (overview | villi | detail) | Cord Histology | Placenta Histology | Placenta Development
Cord Histology
- Placental Cord Histology: Cord overview | Vein | Artery | Artery | Allantois | Epithelium | Cord overview 1 unlabeled | overview 2 unlabeled | unlabeled vein and connective tissue | unlabeled connective tissue | Villi histology | Placenta Histology
Blood Histology
Placental villi with fetal and maternal red blood cell (RBC) detail.
Abnormal Histology
Other Species Placenta
References
- ↑ <pubmed>22606231</pubmed>| PLoS One.
- ↑ Hofbauer J. About the constant occurrence hitherto unknown cellular form elements in the chorionic villus of the human placenta. (Uber das konstante Vorkommen hisher unbekannter zelliger Formelemente in der Chorionzotte der menschlichen Placenta.) Wien. klin. Wehnsohr., vol. 16. , 1905. Giundziige einer Biologie der menschlichen Plazenta. Leipzig.
- ↑ Meyer AW. On the nature, occurrence, and identity of the plasma cells of Hofbauer. (1918) J Morphol. 32(1): 327-350.
Reviews
Articles
Search PubMed
Search Pubmed: Placenta Histology
Glossary Links
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Cite this page: Hill, M.A. (2023, December 2) Embryology Placenta - Histology. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Placenta_-_Histology
- © Dr Mark Hill 2023, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G