Developmental Signals - Retinoic acid
Embryology - 20 Jun 2024 Expand to Translate |
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Introduction
All-trans retinoic acid (atRA) is the transcriptionally active product of vitamin A and is known to play many roles in embryo development.
The compound has been used extensively postnatally in therapeutic treatments, for example in skin disease. Its developmental signalling role is a factor for its known teratogenic effects[2][3] from maternal to conceptus transfer.
Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
| Category:Retinoic acid | Abnormal Development
Some Recent Findings
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More recent papers |
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More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Embryo Retinoic acid | Images <pubmed limit=5>Embryo Retinoic acid</pubmed> |
Endoderm
Chicken antero-posterior endoderm patterning[6]
- Links: Endoderm | Chicken Development
Fetal Gonad
Immunohistochemical localisation of retinoid receptor expression in the human fetal gonad[7]
Neural
Model retinoic acid extracellular signal-regulated kinase and Wnt pathway interactions[8]
RA Is Not Required for Radial Expansion of the Embryonic Cortex
References
- ↑ <pubmed>23829703</pubmed>| Neural Dev.
- ↑ <pubmed>10331090</pubmed>
- ↑ <pubmed>11375780</pubmed>
- ↑ <pubmed>25558812</pubmed>
- ↑ <pubmed>23563268</pubmed>
- ↑ 19516907</pubmed>| PLoS One.
- ↑ Childs AJ, Cowan G, Kinnell HL, Anderson RA, Saunders PTK (2011) Retinoic Acid Signalling and the Control of Meiotic Entry in the Human Fetal Gonad. PLoS ONE 6(6): e20249. PMID 21674038 | PLoS One
- ↑ <pubmed>19642999</pubmed>
Articles
<pubmed>21673209</pubmed>| Can Fam Physician
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Cite this page: Hill, M.A. (2024, June 20) Embryology Developmental Signals - Retinoic acid. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Retinoic_acid
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G