Developmental Signals - Retinoic acid: Difference between revisions

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* '''Visualization of an endogenous retinoic acid gradient across embryonic development'''<ref name=PMID23563268><pubmed>23563268</pubmed></ref> "In vertebrate development, the body plan is determined by primordial morphogen gradients that suffuse the embryo. Retinoic acid (RA) is an important morphogen involved in patterning the anterior-posterior axis of structures, including the hindbrain and paraxial mesoderm. RA diffuses over long distances, and its activity is spatially restricted by synthesizing and degrading enzymes. ...Live imaging of endogenous concentration gradients across embryonic development will allow the precise assignment of molecular mechanisms to developmental dynamics and will accelerate the application of approaches based on morphogen gradients to tissue engineering and regenerative medicine." [[Zebrafish Development]]
* '''Visualization of an endogenous retinoic acid gradient across embryonic development'''<ref name=PMID23563268><pubmed>23563268</pubmed></ref> "In vertebrate development, the body plan is determined by primordial morphogen gradients that suffuse the embryo. Retinoic acid (RA) is an important morphogen involved in patterning the anterior-posterior axis of structures, including the hindbrain and paraxial mesoderm. RA diffuses over long distances, and its activity is spatially restricted by synthesizing and degrading enzymes. ...Live imaging of endogenous concentration gradients across embryonic development will allow the precise assignment of molecular mechanisms to developmental dynamics and will accelerate the application of approaches based on morphogen gradients to tissue engineering and regenerative medicine." [[Zebrafish Development]]
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<pubmed limit=5>Embryo Retinoic acid</pubmed>
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==Endoderm==
[[File:Chicken_antero-posterior_endoderm_patterning_01.jpg|alt=Chicken antero-posterior endoderm patterning cartoon|400px]]
Chicken antero-posterior endoderm patterning<ref name=PMID19516907<pubmed>19516907</pubmed>| [http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005845 PLoS One.]<ref>
==Fetal Gonad==
==Fetal Gonad==



Revision as of 12:15, 31 August 2014

Embryology - 7 May 2024    Facebook link Pinterest link Twitter link  Expand to Translate  
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Introduction

Model for retinoid acid in olfactory development[1]
Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular

Some Recent Findings

  • Visualization of an endogenous retinoic acid gradient across embryonic development[2] "In vertebrate development, the body plan is determined by primordial morphogen gradients that suffuse the embryo. Retinoic acid (RA) is an important morphogen involved in patterning the anterior-posterior axis of structures, including the hindbrain and paraxial mesoderm. RA diffuses over long distances, and its activity is spatially restricted by synthesizing and degrading enzymes. ...Live imaging of endogenous concentration gradients across embryonic development will allow the precise assignment of molecular mechanisms to developmental dynamics and will accelerate the application of approaches based on morphogen gradients to tissue engineering and regenerative medicine." Zebrafish Development
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Search term: Retinoic acid

<pubmed limit=5>Embryo Retinoic acid</pubmed>

Endoderm

Chicken antero-posterior endoderm patterning cartoon

Chicken antero-posterior endoderm patterningCite error: Closing </ref> missing for <ref> tag


Neural

Model retinoic acid extracellular signal-regulated kinase and Wnt pathway interactions.jpg

Model retinoic acid extracellular signal-regulated kinase and Wnt pathway interactions[3]

Mouse embryo cortex radial expansion.jpg

RA Is Not Required for Radial Expansion of the Embryonic Cortex

References

  1. <pubmed>23829703</pubmed>| Neural Dev.
  2. <pubmed>23563268</pubmed>
  3. <pubmed>19642999</pubmed>


Articles

<pubmed>21673209</pubmed>| Can Fam Physician

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Cite this page: Hill, M.A. (2024, May 7) Embryology Developmental Signals - Retinoic acid. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Retinoic_acid

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G