Abnormal Development - Varicella Zoster Virus: Difference between revisions
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==Introduction== | ==Introduction== | ||
[[File:Varicella_zoster_virus.jpg|thumb|Varicella zoster virus (CDC electron micrograph)]] | [[File:Varicella_zoster_virus.jpg|thumb|Varicella zoster virus <br>(CDC electron micrograph)]] | ||
Varicella Zoster Virus or chickenpox maternal infection can be transmitted to the fetus. | Varicella Zoster Virus or chickenpox maternal infection can be transmitted to the fetus. | ||
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{{Viral Links}} | {{Viral Links}} | ||
==Fetal and Neonatal Risks== | ==Fetal and Neonatal Risks== |
Revision as of 14:52, 28 April 2012
Educational Use Only - Embryology is an educational resource for learning concepts in embryological development, no clinical information is provided and content should not be used for any other purpose. |
Introduction
Varicella Zoster Virus or chickenpox maternal infection can be transmitted to the fetus.
Fetal varicella syndrome (FVS) is caused by transplacental infection by the varicella zoster (chickenpox) virus following maternal infection.
Fetal and Neonatal Risks
Risks are dependent on the infection timing.
- before 20 weeks (GA) - FVS can occur with an incidence of about 1%. The lesions can affect the skin, limbs, central and autonomous nervous systems, eyes, cause calcifications, and growth retardation; mortality is high. Lesions typically follow one or several nerve territories, suggesting that damage results from in utero zoster following primary fetal infection.
- during pregnancy - transmission can occur, but is usually asymptomatic; some infants develop zoster postnatally and a few have FVS.
- around delivery - often leads to disseminated neonatal varicella.
Viral Links: viral infection | TORCH | cytomegalovirus | hepatitis | HIV | parvovirus | polio | rubella virus | chickenpox | Lymphocytic Choriomeningitis Virus | Zika virus | human papillomavirus | rotavirus | West Nile virus | varicella virus | vaccination | zoonotic infection | environment | ||
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Some Recent Findings
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Images
WHO Information
Virus History
References
- ↑ <pubmed>22514124</pubmed>
Textbooks
- Medical Microbiology. 4th edition. Baron S, editor. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 55 Togaviruses: Rubella Virus | Chapter 54Alphaviruses (Togaviridae) and Flaviviruses (Flaviviridae) | Table 55-1 Abnormalities Associated with Congenital Rubella Syndrome | Figure 55-3 Incidence rates of rubella USA 1966-1993
- Molecular Biology of the Cell. 4th edition. Alberts B, Johnson A, Lewis J, et al. New York: Garland Science; 2002. Viruses Exploit Host Cell Machinery for All Aspects of Their Multiplication
- Disease Control Priorities in Developing Countries. 2nd edition. Jamison DT, Breman JG, Measham AR, et al., editors. Washington (DC): World Bank; 2006. Chapter 20Vaccine-preventable Diseases
- Antenatal Care: Routine care for the healthy pregnant woman. NICE Clinical Guidelines, No. 62. National Collaborating Centre for Women's and Children's Health (UK). London: RCOG Press; 2008 Mar. 10.8. Rubella
Reviews
<pubmed>16580940</pubmed>
Articles
<pubmed>11297117</pubmed>| eMJA
Search Pubmed
Search Pubmed: Varicella Zoster Virus | [1] | fetal varicella syndrome
Environmental Links: Introduction | low folic acid | iodine deficiency | Nutrition | Drugs | Australian Drug Categories | USA Drug Categories | thalidomide | herbal drugs | Illegal Drugs | smoking | Fetal Alcohol Syndrome | TORCH | viral infection | bacterial infection | fungal infection | zoonotic infection | toxoplasmosis | Malaria | maternal diabetes | maternal hypertension | maternal hyperthermia | Maternal Inflammation | Maternal Obesity | hypoxia | biological toxins | chemicals | heavy metals | air pollution | radiation | Prenatal Diagnosis | Neonatal Diagnosis | International Classification of Diseases | Fetal Origins Hypothesis |
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- Department of Health and Ageing Immunise Australia Program Website | The Australian Immunisation Handbook 9th Edition 2008
- World Health Organization (WHO)
- International Committee on Taxonomy of Viruses
Glossary Links
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Cite this page: Hill, M.A. (2024, June 16) Embryology Abnormal Development - Varicella Zoster Virus. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Varicella_Zoster_Virus
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G