Molecular Development - Developmental Enhancers

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Introduction

Draft Page

Developmental gene expression context model.jpg

Developmental Gene Expression Model[1]

Molecular Development - Developmental Enhancers


Molecular Links: molecular | genetics | epigenetics | mitosis | meiosis | X Inactivation | Signaling | Factors | Mouse Knockout | microRNA | Mechanisms | Developmental Enhancers | Protein | Genetic Abnormal | Category:Molecular


Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular
Mechanism Links: mitosis | cell migration | epithelial invagination | epithelial mesenchymal transition | mesenchymal epithelial transition | epithelial mesenchymal interaction | morphodynamics | tube formation | apoptosis | autophagy | axes formation | time | molecular

Some Recent Findings

  • Topology of mammalian developmental enhancers and their regulatory landscapes[1] "How a complex animal can arise from a fertilized egg is one of the oldest and most fascinating questions of biology, the answer to which is encoded in the genome. Body shape and organ development, and their integration into a functional organism all depend on the precise expression of genes in space and time. The orchestration of transcription relies mostly on surrounding control sequences such as enhancers, millions of which form complex regulatory landscapes in the non-coding genome. Recent research shows that high-order chromosome structures make an important contribution to enhancer functionality by triggering their physical interactions with target genes."
More recent papers
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Search term: Developmental Enhancers

<pubmed limit=5>Developmental Enhancers</pubmed>

References

  1. 1.0 1.1 <pubmed>24153303</pubmed>


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Cite this page: Hill, M.A. (2019, July 21) Embryology Molecular Development - Developmental Enhancers. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Molecular_Development_-_Developmental_Enhancers

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© Dr Mark Hill 2019, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G