File:Mouse E9 cervical intersomitic vessels B.jpg
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Mouse - Cervical Intersomitic Vessels
- A The various stages of cervical intersomitic vessel development can be segmented as visualized as surface renderings in the 16 somite mouse embryo (Theiler Stage 13 - Theiler Stage 14) The vessels along the right side of the embryo and surrounding somites 1 through 16 are labelled as: DA (red), ISA (pink), ISV (blue), VTA (vertebral artery), DLAV (dorsal longitudinal anastomotical vessel) and PNVP (green) (perineual vascular plexus) , ACV (anterior cardinal vein) and CCV (cyan) (common cardinal vein) , UV (dark pink), UV plexus (purple), and PCV (blue). Somites 1, 5, 10 and 15 are numbered as S-1, S-5, S-10 and S-15.
- B Branches of PECAM-1 expression originating from the tips of the ISAs (yellow arrowheads) were observed to turn towards the location of the future PCV (posterior cardinal vein).
- C A second branch from the ISA was also observed to extend in a predominantly anterior direction (pink arrowheads) to connect up with other ISAs, eventually forming the DLAV. PECAM-1 expression along the location of the expected PCV was observed to lag development of the ISAs and is discontinuous (yellow arrowheads).
- D The PNVP develops through remodelling of the VTA and DLAV. Branches initiate medially from the DLAV (pink arrowhead), begin to remodel into simple mesh (blue arrowhead), and eventually remodel into a fine structured capillary plexus surrounding the neural tube. Note at this stage that the first ISA has regressed.
Scale bars represent 100 microns.
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- Mouse Vascular Links: Image - Cervical intersomitic_vessels E9 | Image - dorsolateral view | Image - cervical intersomitic vessels | Image - lateral view | Image - segment vessels alone | Mouse Development | Cardiovascular System Development
Reference
<pubmed>18682734</pubmed>| PLoS ONE
Copyright
© 2008 Walls et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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current | 17:46, 22 August 2014 | 1,714 × 1,142 (175 KB) | Z8600021 (talk | contribs) | ==Mouse - Cervical Intersomitic Vessels== * '''A''' The various stages of cervical intersomitic vessel development can be segmented as visualized as surface renderings in the 16 somite mouse embryo (Theiler Stage 13 -... |
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