Week 1

From Embryology

Introduction

Key Events of Human Development during the first week (week 1) following fertilization or Clinical week 3 (LMP).


Links: 2009 Lecture - Fertilization | 2009 Lecture - Week 1 and 2 | Oocyte | Spermatozoa | Fertilization

Human-oocyte to blastocyst.jpg

Human-oocyte to blastocyst

Day
Stage
Event
1
Secretory PhaseStage 1 Early zygote.jpg Fertilization, Secretory Phase
2
Stage 2 Stage2.jpg Week1 001 icon.jpg Morula, Blastula
3
  Week1 001 icon.jpg
4
Stage 3 CSt3.jpg Blastocyst Hatching (zona pellucida lost)
5
  CSt3.jpg

Blastocyst (free floating)

6
Stage 4 Adplantation
7
Stage 5 File:2ndwk.jpg

Week 1 Movies

Follicle 001 icon.jpg Fertilization 002 icon.jpg Pronuclear fusion 001 icon.jpg Week1 001 icon.jpg Ovulation icon.jpg Fertilization 001 icon.jpg
Ovulation Fertilization Pronuclear Fusion Week 1 Ovulation in the rabbit Fertilization in the mouse

Week 1 Abnormalities

Additional Information

Dizygotic Twinning

Dizygotic twins (fraternal, non-identical) arise from separate fertilization events involving two separate oocyte (egg, ova) and spermatozoa (sperm).

Monoygotic Twinning

Monoygotic twins (identical) produced from a single fertilization event (one fertilised egg and a single spermatazoa, form a single zygote), these twins therefore share the same genetic makeup. Occurs in approximately 3-5 per 1000 pregnancies, more commonly with aged mothers. The later the twinning event, the less common are initially separate placental membranes and finally resulting in conjoined twins.

Week Week 1 Week 2
Day 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Cell Number 1 1 2 16 32 128 bilaminar
Event Ovulation fertilization First cell division Morula Early blastocyst Late blastocyst

Hatching

Implantation starts X inactivation
Follicle 001 icon.jpg Early zygote.jpg Human embryo day 2.jpg Human embryo day 3.jpg Human embryo day 5.jpg CSt3.jpg Week2 001 icon.jpg
Monoygotic

Twin Type

Diamniotic

Dichorionic

Diamniotic

Monochorionic

Monoamniotic

Monochorionic

Conjoined

Table based upon: Twinning. Hall JG. Lancet. 2003 Aug 30;362(9385):735-43. Review. PMID: 12957099


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Cite this page: Hill, M.A. (2024, May 4) Embryology Week 1. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Week_1

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G