Timeline human development

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Embryology - 27 Apr 2024    Facebook link Pinterest link Twitter link  Expand to Translate  
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Introduction

From a single cell to a newborn infant in 9 months.
Early zygote.jpg Newborn.jpg Human development timeline graph 01.jpg

This page is organised to show week by week human development features and approximate timing of key events with more detailed information about specific events in different systems. For a less detailed timeline see week by week.

Embryonic Development
  • "Weeks" refer to embryonic development from fertilization.
    • Clinical weeks (shown in brackets) or Gestational Age GA) is from the first day of the Last Menstrual Period (LMP).
  • "Stages" refer to the Carnegie stages of development.
  • "Timing" refers to days from fertilization or post conception age (PC), not the clinical or gestational age (GA) calculated from LMP (add 2 weeks).
  • Dates and staging are also "ideal", and there is significant biological variability in the general timing of events.
  • Week 1 to Week 8 (GA 10)are considered the embryonic period of development.
  • Week 9 to week 37 (GA 11-39) or birth are considered the fetal period of development.
  • First month (4 weeks) after birth is the neonatal period of development.


Each developmental feature is linked to online content with more detailed information and resources such as images and movies. The superscript numbers are the original source references. There are similar "timelines" for other species shown below.


Timeline Links: human timeline | mouse timeline | mouse detailed timeline | chicken timeline | rat timeline | zebrafish timeline | Medaka | comparative | Category:Timeline
Human Trimesters - Systems  
Period: first trimester timeline | second trimester timeline | third trimester timeline

Systems: bone timeline | eye neural crest timeline | heart abnormality timeline | hearing timeline | hearing EAM timeline | muscle timeline | ovary timeline | pelvis timeline | placental villi timeline | shoulder timeline | smell timeline | spleen timeline | ventricular timeline

Historic  
upper limb ossification timeline | lower limb ossification timeline | 1932 Guinea pig day 11-21 | 1933 Guinea pig day 21-35
Embryology History: 1600-1699 | 1700-1799 | 1800-1899 | 1900-1909 | 1910-1919 | 1920-1929 | 1930-1939 | 1940-1949 | 1950-1959 | 1960-1969 | 1970-1979 | 1980-1989 | 1990-1999 | Historic Papers | Embryologists

Human Systems

Alphabetical: bone timeline | eye neural crest timeline | heart abnormality timeline | hearing EAM timeline | muscle timeline | ovary timeline | placental villi timeline | shoulder timeline | smell timeline | spleen timeline | ventricular timeline


Second Trimester

(GA Clinical Week 14) Second Trimester


Third Trimester

Postnatal

Week
Stage
Event
+1
Normal Newborn Neural Exam Movies  
Normal Newborn Neural Exam Movies

The newborn neuromuscular system can be initially assessed by 6 quick tests (posture, square window, arm recoil, popliteal angle, scarf sign and heel to ear). The following short videos show clinical examination of these assessments and a number of neonatal reflexes.

Later developmental assessment includes behaviour, reflexes (primitive and postural), muscular tone, and motor (gross, fine, co-ordination).

Normal Newborn Neural Exam Movies

Newborn Behaviour
Newborn-normal-behaviour.jpg
 ‎‎Behaviour
Page | Play
Newborn n 02.jpg
 ‎‎Cranial Nerves
Page | Play
Newborn Tone
Newborn n 03.jpg
 ‎‎Resting Posture
Page | Play
Newborn n 04.jpg
‎‎ Tone Upper Limb
Page | Play
Newborn n 05.jpg
‎‎ Arm Traction
Page | Play
Newborn n 06.jpg
 ‎‎Arm Recoil
Page | Play
Newborn n 07.jpg
 ‎‎Scarf Sign
Page | Play
Newborn n 08.jpg
 ‎‎Hand Position
Page | Play
Newborn n 09.jpg
 ‎‎Lower Limb
Page | Play
Newborn n 10.jpg
 ‎‎Leg Traction
Page | Play
Newborn n 11.jpg
 ‎‎Leg Recoil
Page | Play
Newborn n 12.jpg
 ‎‎Popliteal Angle
Page | Play
Newborn n 13.jpg
 ‎‎Heel to Ear
Page | Play
Newborn n 14.jpg
 ‎‎Neck Tone
Page | Play
Newborn n 15.jpg
 ‎‎Head Lag
Page | Play
Newborn n 16.jpg
 ‎‎Head Control
Page | Play
Newborn Positions
Newborn n 17.jpg
 ‎‎Prone Position
Page | Play
Newborn n 18.jpg
 ‎‎Ventral Suspend
Page | Play
Newborn n 19.jpg
 ‎‎Vertical Suspend
Page | Play
Newborn Reflexes
Newborn n 20.jpg
 ‎‎Tendon Reflexes
Page | Play
Newborn n 21.jpg
 ‎‎Plantar Reflex
Page | Play
Newborn n 22.jpg
 ‎‎Reflex Suck,Root
Page | Play
Newborn n 23.jpg
 ‎‎Moro Reflex
Page | Play
Newborn n 24.jpg
 ‎‎Galant Reflex
Page | Play
Newborn n 25.jpg
 ‎‎Stepping Reflex
Page | Play
Newborn n 26.jpg
 ‎‎Grasp Reflex
Page | Play
Newborn Head
Newborn n 27.jpg
‎‎ Head Shape
Page | Play
Newborn n 28.jpg
‎‎Head Circumference
Page | Play
Neural Exam Movies: normal behaviour | cranial nerves | Newborn Tone - resting posture | upper extremity‎ | arm traction | arm recoil | scarf sign | hand position | lower extremity | leg traction‎ | leg recoil‎‎ | popliteal angle‎ | heel to ear | neck tone | head lag‎ | head control | Newborn Positions - prone | ventral suspension | vertical suspension | Newborn Reflexes - deep tendon reflexes | plantar reflex‎ | suck, root | Moro | Galant | stepping‎ | grasp | Newborn Head - head shape and sutures‎ | head circumference‎ | Neonatal Diagnosis


+2
 
+3
 
+4
  vision - eye globe growth plateaus after 42 weeks of gestation[1]  
+5
   
Month
  testis | spermatozoa - about 2 months of age, primordial germ cells (gonocytes) are replaced by adult dark (Ad) and pale (Ap) spermatogonia forming the spermatogonial stem cell (SSC) population that at puberty will commence differentiation into spermatozoa.
Year
 
Year 1
  neural Hearing (6 months to 5 years) thalamocortical afferents to the deeper cortical layers mature and are the first source of input to the auditory cortex[2]


Normal 12 Month Neural Exam Movies  
Normal 12 Month Neural Exam Movies

The following short videos show clinical examination of neural development assessments and a number of reflexes.


12 Months Neural Exam Movies: Shy | Social and Language | Cranial Nerves | Tone - Tone | Reflexes - deep tendon reflexes | plantar reflex‎ | Parachute | Pincer Grasp | Beads in the Cup | Play Ball | Transition in and out of Sitting | Creeping | Stoop and Recover | Motor/Gait - Stand, Walks with Support | Toddler’s Gait | Head Circumference | Neural Exam Movies
Year 2
   
Year 3
  Adrenal - Year 3 zona reticularis present.


Normal 30 Month Neural Exam Movies  
Normal 30 Month Neural Exam Movies

The following short videos show clinical examination of neural development assessments and a number of reflexes.


Neural Exam Movies: Establishing Relationship | Follows Commands | Points to Pictures | Names Pictures | Response to Questions | Pointing to and Naming Body Parts | Motor/Coordination - Using Puppets | Using Measuring Tape | Block Tower | Drawing | Tone | Deep Tendon Reflex | Kicking and Throwing a Ball | Walking, Running
4
   
5
  neural hearing - (5 to 12 years) commissural and association axons in the superficial cortical layers allows communication between subdivisions of the auditory cortex[2]
7-13
  puberty - Female
9-15
puberty - Male

References

  1. Paquette LB, Jackson HA, Tavaré CJ, Miller DA & Panigrahy A. (2009). In utero eye development documented by fetal MR imaging. AJNR Am J Neuroradiol , 30, 1787-91. PMID: 19541779 DOI.
  2. 2.0 2.1 Moore JK. (2002). Maturation of human auditory cortex: implications for speech perception. Ann Otol Rhinol Laryngol Suppl , 189, 7-10. PMID: 12018354


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Cite this page: Hill, M.A. (2024, April 27) Embryology Timeline human development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Timeline_human_development

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G