Blastocyst Day 3-6 Movie

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Movie shows in vitro development of a human morula to blastocyst stage occurring between day 3 and day 6 post-fertilization.

Timing shown below are "movie times" not the "developmental days".

00:00 day 3 - Initially a solid mass of cells morula stage enclosed by the zona pellucida.

00:18 day 4 - blastocoel formation

00:22 - inner cell mass (embryoblast)

00:29 - maximal expansion of blastocyst in ZP

00:31 - contraction

00:32 - re-expansion

00:37 day 5 - contraction

00:38 - re-expansion

00:39 - contraction (collapse)

00:40 - re-expansion (blastocoel enlargement)

00:41 - commence blastocyst hatching (1 o'clock position)

00:44 day 6 - complete hatching, blastocyst expansion (inner cell mass 2 o'clock position)

00:47 - trophoblast layer thickens

00:53 movie finishes


Blastocyst Movie Links: MP4 day 3-6 | Blastocyst Day 5-6 Movie | MP4 day 5-6 | Blastocyst Hatching Movie | MP4 Hatching day 5-6 | Blastocyst Development | Movies
Carnegie stage 3 | Carnegie stage 4 | Carnegie stage 5
Human blastocyst day 1-6.jpg

Human blastocyst development (in vitro) from day 1 to day 6.


Links: Zygote | Morula | Blastocyst | Zona pellucida | Implantation | Carnegie stage 3 | Carnegie stage 4 | Carnegie stage 5


Week: 1 2 3 4 5 6 7 8
Carnegie stage: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23

Reference

Connie C Wong, Kevin E Loewke, Nancy L Bossert, Barry Behr, Christopher J De Jonge, Thomas M Baer, Renee A Reijo Pera Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat. Biotechnol.: 2010, 28(10);1115-21 PubMed 20890283

| Nat Biotechnol.


Copyright

Reprinted by permission from Macmillan Publishers Ltd: Nat Biotechnol. (Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Wong CC, Loewke KE, Bossert NL, Behr B, De Jonge CJ, Baer TM, Pera RA. Nat Biotechnol. 2010 Oct 3. [Epub ahead of print] PMID 20890283), copyright (2010)


Licensee: Mark A Hill License Date: Oct 06, 2010 License Number: 2523401420894 Publication: Nature Biotechnology Title: Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage Type Of Use: Web Site