|Embryology - 29 Nov 2020 Expand to Translate|
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There are many steps in the preparation and processing of tissue sections that can introduce artefacts into the original tissue. This page introduces some of the steps in tissue preparation where this can occur and the type of artefact that appears in the final tissue. The pages on histology fixatives and stains should be read in conjunction with this page.
Draft page - Notice removed when completed.
- Prefixation artifacts
- Fixation artifacts
- Artifacts related to bone tissue
- Tissue-processing artifacts
- Artifacts related to microtomy
- Artifacts related to floatation and mounting
- Staining artifacts
- Mounting artifacts
Anything that may have been done to the tissue before it has been preserved by fixation. This includes handling, physical distortion, drug treatments or injections, tissue degeneration, or poor tissue preparation for fixation.
Fixative solution osmolality
- Hypertonic can cause cellular shrinkage and increased extracellular spaces.
- Hypotonic can cause cell swelling.
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Cite this page: Hill, M.A. (2020, November 29) Embryology Histology Artifacts. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Histology_Artifacts
- © Dr Mark Hill 2020, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G