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:'''Links:''' [[:File:Mouse limb skeleton cartoon.jpg|Image - Mouse limb skeleton cartoon]] | [[:File:Mouse limb tissue development.jpg|Image - Mouse limb tissue development]] | [[Musculoskeletal_System_-_Limb_Development|Limb Development]] | [[Mouse Development]]  
:'''Links:''' [[:File:Mouse limb skeleton cartoon.jpg|Image - Mouse limb skeleton cartoon]] | [[:File:Mouse limb tissue development.jpg|Image - Mouse limb tissue development]] | [[Musculoskeletal_System_-_Limb_Development|Limb Development]] | [[Mouse Development]]  
{{CarnegieComparisonHRM}}


Cartoon has been cropped and relabelled from Figure 5 and legend edited.
Cartoon has been cropped and relabelled from Figure 5 and legend edited.

Revision as of 14:27, 4 January 2012

Mouse Limb Tissue Development

Change in cell types and tissue formation as a function of mouse developmental stage.

  • Highlighted are key events during bone, muscle, nerve and skin formation.
  • Some key molecules in these processes are shown.
  • Cell type morphologies for different stages of skeletal development.


Links: Image - Mouse limb skeleton cartoon | Image - Mouse limb tissue development | Limb Development | Mouse Development


Species Embryonic Comparison Timeline
Carnegie Stage
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
Human Days 1 2-3 4-5 5-6 7-12 13-15 15-17 17-19 20 22 24 28 30 33 36 40 42 44 48 52 54 55 58
Mouse Days 1 2 3 E4.5 E5.0 E6.0 E7.0 E8.0 E9.0 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16
Rat Days 1 3.5 4-5 5 6 7.5 8.5 9 10.5 11 11.5 12 12.5 13 13.5 14 14.5 15 15.5 16 16.5 17 17.5
Note these Carnegie stages are only approximate day timings for average of embryos. Links: Carnegie Stage Comparison
Table References  
Human

O'Rahilly R. (1979). Early human development and the chief sources of information on staged human embryos. Eur. J. Obstet. Gynecol. Reprod. Biol. , 9, 273-80. PMID: 400868
Otis EM and Brent R. Equivalent ages in mouse and human embryos. (1954) Anat Rec. 120(1):33-63. PMID 13207763

Mouse
Theiler K. The House Mouse: Atlas of Mouse Development (1972, 1989) Springer-Verlag, NY. Online
OTIS EM & BRENT R. (1954). Equivalent ages in mouse and human embryos. Anat. Rec. , 120, 33-63. PMID: 13207763

Rat
Witschi E. Rat Development. In: Growth Including Reproduction and Morphological Development. (1962) Altman PL. and Dittmer DS. ed. Fed. Am. Soc. Exp. Biol., Washington DC, pp. 304-314.
Pérez-Cano FJ, Franch À, Castellote C & Castell M. (2012). The suckling rat as a model for immunonutrition studies in early life. Clin. Dev. Immunol. , 2012, 537310. PMID: 22899949 DOI.

Cartoon has been cropped and relabelled from Figure 5 and legend edited.

Reference

<pubmed>22174793</pubmed>


This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

Figure 5. Journal.pone.0028358.g005.jpg

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current13:00, 13 February 2013Thumbnail for version as of 13:00, 13 February 20131,280 × 767 (161 KB)Z8600021 (talk | contribs)change width to 1280 pixels
12:49, 4 January 2012Thumbnail for version as of 12:49, 4 January 20121,200 × 743 (164 KB)S8600021 (talk | contribs)==Mouse Limb Tissue Development== Graphical depiction of the change in cell types and tissue formation as a function of developmental stage, highlighting key events during bone, muscle, nerve and skin formation. Some key molecules known to participate i

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