Developmental Signals - Homeobox

From Embryology


The family of Hox-proteins has been a focus of research for over 30 years.

Notice - Mark Hill
Currently this page is only a template and will be updated (this notice removed when completed).

Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular

Some Recent Findings

  • Proposed Hox protein classification[1]"Our classification scheme offers a higher-resolution classification that is in accordance with phylogenetic as well as experimental data and, thereby, provides a novel basis for experiments, such as comparative and functional analyses of Hox-proteins."
  • Homeobox A7 up-regulation of epidermal growth factor receptor expression in human granulosa cells[2]"Our present study reveals a novel mechanistic role for HOXA7 in modulating granulosa cell proliferation via the regulation of EGFR. This finding contributes to the knowledge of the pro-proliferation effect of HOXA7 in granulosa cell growth and differentiation."


Proposed Hox protein classification.jpg
Proposed Hox protein classification[1]


Developmental patterning signal.



Signaling Pathway


  1. 1.0 1.1 <pubmed>20520839</pubmed>| PLoS One
  2. <pubmed>20540809</pubmed>| Reprod Biol Endocrinol.

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External Links

Cite this page: Hill, M.A. (2020, June 2) Embryology Developmental Signals - Homeobox. Retrieved from

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© Dr Mark Hill 2020, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G