Abnormal Development - Radiation: Difference between revisions

Revision as of 00:20, 7 September 2010

Notice - Mark Hill

Currently this page is only a template and will be updated (this notice removed when completed).

Introduction

This page introduces the possible effects of radiation on development. The two main sources of exposure are environmental and those used for medical diagnostic or therapeutic purposes.

Studies have shown that in maternal X-ray diagnostic examination, where the beam does not irradiate the embryo/fetus directly (maternal skull and chest X-ray), the absorbed dose for the embryo or fetus is extremely low (less than 0.01 mGy).

Treatment of hyperthyroidism with 131 Iodine in a pregnant woman is strictly contraindicated due to the effects on the developing embryonic thyroid gland.

Some Recent Findings

Malformations in a chornobyl-impacted region^[1] "The overall rate of neural tube defects in Rivne is among the highest in Europe (22.2 per 10,000 live births). The rates of conjoined twins and teratomas also seem to be elevated. In Polissia, the overall rates of neural tube defects are even higher (27.0 vs 18.3, respectively; odds ratio: 1.46 [95% confidence interval: 1.13-1.93]), and the rates of microcephaly and microphthalmia may also be elevated."
^[2]

Diagnostic Radiography

A recent Australian review study has shown minimal effects of standard diagnostic radiography underspecific conditions.

"The only adverse effect statistically proven at the dose levels associated with diagnostic radiation procedures is a very small increase in childhood malignancy, with an estimated increase of one additional cancer death per 1700 10 mGy exposures. The important exception was the risk to the fetal thyroid from radioiodine exposure after 12 weeks' gestation."

Lowe SA. Diagnostic radiography in pregnancy: risks and reality. Aust N Z J Obstet Gynaecol. 2004 Jun;44(3):191-6.

email Dr S.A. Lowe Department of Medicine, Royal Hospital for Women, New South Wales, Randwick, Sydney, Australia

References

↑ <pubmed>20308207</pubmed>
↑ <pubmed>19180648</pubmed>

Reviews

Articles

Search Pubmed

June 2010 "Abnormal Development Radiation"

Search Pubmed: Abnormal Development Radiation

External Links

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Cite this page: Hill, M.A. (2024, May 19) Embryology Abnormal Development - Radiation. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Radiation

What Links Here?

[1] <pubmed>20308207</pubmed>

[2] <pubmed>19180648</pubmed>

[1]

[2]

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 ==Some Recent Findings==
-<ref><pubmed>19180648</pubmed></ref>
+{|
+|-bgcolor="F5FAFF"
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+* '''Malformations in a chornobyl-impacted region'''<ref><pubmed>20308207</pubmed></ref> "The overall rate of neural tube defects in Rivne is among the highest in Europe (22.2 per 10,000 live births). The rates of conjoined twins and teratomas also seem to be elevated. In Polissia, the overall rates of neural tube defects are even higher (27.0 vs 18.3, respectively; odds ratio: 1.46 [95% confidence interval: 1.13-1.93]), and the rates of microcephaly and microphthalmia may also be elevated."
+* <ref><pubmed>19180648</pubmed></ref>
+|}
 ==Diagnostic Radiography==