|
|
Line 4: |
Line 4: |
| | [[File:Stage11 sem6.jpg|250px]] | | | [[File:Stage11 sem6.jpg|250px]] |
| | | | | |
| | ===Facts=== |
| | |
| | Week 4, 23 - 26 days, 2.5 - 4.5 mm, Somite Number 13 - 20 |
| | |
| | Gestational Age - week 6 |
| | |
| | ===Events=== |
| | |
| | |
| | Ectoderm: Neural tube continues to close, Rostral neuropore closes |
| | |
| | Mesoderm: continued segmentation of paraxial mesoderm (13 - 20 somite pairs), heart tube bending |
| | |
| This early week 4 embryonic stage shows key features of heart tube and neural plate to tube development. | | This early week 4 embryonic stage shows key features of heart tube and neural plate to tube development. |
|
| |
|
Line 21: |
Line 34: |
| | | | | |
| |} | | |} |
|
| |
| ===Facts===
| |
|
| |
| Week 4, 23 - 26 days, 2.5 - 4.5 mm, Somite Number 13 - 20
| |
|
| |
| ===Events===
| |
|
| |
|
| |
| Ectoderm: Neural tube continues to close, Rostral neuropore closes
| |
|
| |
| Mesoderm: continued segmentation of paraxial mesoderm (13 - 20 somite pairs), heart tube bending
| |
|
| |
|
|
| |
|
Revision as of 07:05, 6 October 2012
Introduction
|
|
Facts
Week 4, 23 - 26 days, 2.5 - 4.5 mm, Somite Number 13 - 20
Gestational Age - week 6
Events
Ectoderm: Neural tube continues to close, Rostral neuropore closes
Mesoderm: continued segmentation of paraxial mesoderm (13 - 20 somite pairs), heart tube bending
This early week 4 embryonic stage shows key features of heart tube and neural plate to tube development.
The embryo is still transparent enough to view the underlying somite and transverse septum development.
The embryo is still quite small and is comparable in size to the external yolk sac.
There are a number of different images and resources available for this embryonic stage including:
|
Lateral (right) view of embryo
|
|
|
Features
rostral neuropore closing, forebrain, neural tube in region of developing spinal cord, somites, caudal neuropore, connecting stalk, amnion
Identify: heart, rostral (cranial, anterior) neuropore closing, forebrain, neural tube in region of developing spinal cord, somites, caudal neuropore, connecting stalk, amnion
- Links: Week 4 | Somitogenesis | Placodes | Lecture - Mesoderm | Lecture - Ectoderm | Lecture - Early Vascular | Science Practical | Category:Carnegie Stage 11 | Stage 12
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Bright Field
|
|
|
Embryo dorsal view
|
Embryo ventral with 1 mm scale bar
|
Embryo lateral view
|
Select image below to open full-size.
BF3 - ventral with scale bar
- Stage 11 Images: BF1 - dorsal view | BF2 - lateral view | BF3 - ventral with scale bar | BF4 - ventral view | BF5 - lateral view | BF6 - ventral view | BF7 - Kyoto embryo | BF8 - ventral head | BF9 - ventral head | BF10 - dorsal neural | BF11 - ventral embryo and yolk sac | Scanning EM embryo | Carnegie stage 11
Scanning EM
This is a scanning EM of the embryo dorsal view showing the neural tube closing with open neuropores and the paired somites visible through the thin ectoderm. Features: surface ectoderm, neural tube, cranial (anterior) neuropore, caudal (posterior) neuropore, somites, heart, cut edge of amnion, 24 days, 13 somite pairs
|
This is a scanning EM of the embryo fractured close to the midline to show the hindbrain rhombomeres. Features: surface ectoderm, neural tube, hindbrain rhombomeres, forebrain, buccopharyngeal membrane, yolk sac, 25 days, 19 somite pairs
|
This is a scanning EM of the embryo superior dorsal view showing the paired otic placodes sinking into the surface at the level of the hindbrain. Features: surface ectoderm, paired otic placodes, pharyngeal arches heart, 25 days, 19 somite pairs
|
This is a scanning EM of the embryo dorsolateral view showing the neural tube closing with open neuropores and the paired somites visible through the thin ectoderm. Features: surface ectoderm, neural tube, cranial (anterior) neuropore, caudal (posterior) neuropore, somites, heart, cut edge of amnion, 24 days, 13 somite pairs
|
This is a scanning EM of the embryo fractured to show the neural tube, notochord and somites. Features: surface ectoderm, neural tube, notochord, somites, somitocoels, dorsal aortas, gastrointestinal tract, 25 days, 19 somite pairs
|
This is a labeled version of the scanning EM of the fractured embryo
|
Buccopharyngeal Membrane
Low power ventral view of the Buccopharyngeal Membrane
Higher power ventrolateral view of the Buccopharyngeal Membrane
Close up view of the degenerating Buccopharyngeal Membrane
Neuropores
Neural Crest
Image Source: Scanning electron micrographs of the Carnegie stages of the early human embryos are reproduced with the permission of Prof Kathy Sulik, from embryos collected by Dr. Vekemans and Tania Attié-Bitach. Images are for educational purposes only and cannot be reproduced electronically or in writing without permission.
Embryonic Development
Kyoto Collection
View: This is a dorsolateral view of embryo. Amniotic membrane removed.
Image source: Embryology page Created: 19.03.1999
Image source: The Kyoto Collection images are reproduced with the permission of Prof. Kohei Shiota and Prof. Shigehito Yamada, Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Kyoto, Japan for educational purposes only and cannot be reproduced electronically or in writing without permission.
Carnegie Collection
- Carnegie stage 11: 6344 dorsolateral | 6344 dorsal | 6784 ventral | 6050 right
iBook - Carnegie Embryos
|
|
- iTunes link | iBook Store
- Description - Imagine the excitement of seeing this incredible early period of human development for the first time. Now consider that much of our initial understanding of human development is based upon study of historic embryo collections. You can now look at these historic images of the first 8 weeks after fertilisation and explore for yourself the changes that occur in human development during this key period. This current book is designed as an atlas of the Carnegie embryo stages with some brief notes and additional information covering the first 8 weeks of development. These images are from from the beginning of last century and are one of the earliest documented series of human embryos collected for basic research and medical education on development. I hope you enjoy learning about the amazing early events that begin to make and shape us. This is the second book in a series of educational releases from UNSW Embryology.
- Release: First Edition - Mar 12, 2012 ISBN 978-0-7334-3148-7 Print Length 82 Pages, 25.8 MB Language English.
- PDF Preview version 3.87 MB (Read the associated information, this is an edited educational preview version with many features not functioning).
- The current website also includes numerous embryo images from this textbook (see Embryonic Development and Carnegie Embryos).
|
Histology
Stage 11 histology links: optic pit | optic vesicle-hindbrain | neural tube roof plate 1 | neural tube roof plate 2
Historic Embryology
- Historic Papers: 13-14 Somites | Carnegie Institution No.131 A human embryo with 14 pairs of somites | Carnegie Institution No.124 A human embryo with 17 pairs of somites | Carnegie Institution No.72 Description of a human embryo having twenty paired somites | Text-Book of Embryology (1921) Fig. 84
Dorsolateral view drawing 14 somite pairs, 24 days (Heuser 1930).
Sagittal (midline) section drawing of 17 somite pairs (Attwell 1930).
Ventral and lateral view drawing of 19 somite pairs, approx 25 days (Attwell 1930).
Ventral and lateral view drawing of 20 somite pairs (Davis 1923).
Dorso-lateral view of human embryo with fourteen pairs of mesodermal somites (Kollmann).
Lateral view of human embryo of 2.6 mm (His, from Keibel and Mall).
Additional Images
Embryo with directions of view
- Carnegie Stages: 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Cite this page: Hill, M.A. (2024, June 15) Embryology Carnegie stage 11. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Carnegie_stage_11
- What Links Here?
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G