Developmental Signals - Notch: Difference between revisions
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==Introduction== | ==Introduction== | ||
[[File:Notch structure cartoon.jpg|thumb|350px|alt=Notch structure cartoon|Notch structure cartoon<ref><pubmed>19255248</pubmed></ref>]] | [[File:Notch structure cartoon.jpg|thumb|350px|alt=Notch structure cartoon|Notch structure cartoon<ref name=PMID19255248><pubmed>19255248</pubmed></ref>]] | ||
The notch proteins were first identified in drosophila development and have since been identified as regulators of cell fate decisions during development. These are a family of cell surface transmembrane receptors that pass once through the plasma membrane. | The notch proteins were first identified in drosophila development and have since been identified as regulators of cell fate decisions during development. These are a family of cell surface transmembrane receptors that pass once through the plasma membrane. | ||
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<pubmed limit=5>Notch</pubmed> | <pubmed limit=5>Notch</pubmed> | ||
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==Notch Signaling== | |||
[[File:Notch signaling pathway cartoon 02.jpg|600px|alt=Notch signaling pathway cartoon]] | |||
Notch signaling pathway<ref name=PMID19255248><pubmed>19255248</pubmed></ref> | |||
==Notch Receptors== | ==Notch Receptors== | ||
Revision as of 21:07, 4 February 2015
Embryology - 23 May 2024 Expand to Translate |
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Introduction
The notch proteins were first identified in drosophila development and have since been identified as regulators of cell fate decisions during development. These are a family of cell surface transmembrane receptors that pass once through the plasma membrane.
- Notch Links: Notch structure cartoon | Notch signaling pathway cartoon | Notch and signaling pathway cartoon | Developmental Signals - Notch | Molecular Factors
Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
Some Recent Findings
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More recent papers |
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Notch <pubmed limit=5>Notch</pubmed> |
Notch Signaling
Notch signaling pathway[1]
Notch Receptors
NOTCH1
NOTCH2
NOTCH3
- Notch3 activation retains mammary luminal cell in a nonproliferative state.[8]
NOTCH4
Notch Ligands
- JAG1
- JAG2
- DLL1
- DLL3
- DLL4
Functions
Developmental patterning signal.
Mesoderm Development
Cartilage Development
Muscle Regeneration
Notch signalling in muscle regeneration[9]
Hypothalamus Development
Hypothalamus Development Gene Interaction Model[10]
- Links: Hypothalamus Development
References
- ↑ 1.0 1.1 <pubmed>19255248</pubmed>
- ↑ 2.0 2.1 <pubmed>24304493</pubmed>| BMC Dev Biol.
- ↑ <pubmed>24927569</pubmed>
- ↑ <pubmed>20513039</pubmed>
- ↑ <pubmed>19590010</pubmed>
- ↑ <pubmed>19590010</pubmed>
- ↑ <pubmed>19161597</pubmed>
- ↑ <pubmed>24100291</pubmed>
- ↑ <pubmed>24472470</pubmed>| BMC Dev Biol.
- ↑ 24360028<pubmed>24360028</pubmed>| Neural Dev.
Reviews
<pubmed></pubmed> <pubmed></pubmed> <pubmed></pubmed> <pubmed>23165243</pubmed> <pubmed> 22399351</pubmed> <pubmed>22397947</pubmed> <pubmed>21828089</pubmed>
Search Pubmed
Search Bookshelf Notch
Search Pubmed Now: Notch Signaling
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- OMIM - NOTCH 1
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, May 23) Embryology Developmental Signals - Notch. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Notch
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G