Week 4: Difference between revisions
(New page: Key Events of Human Development during the forth week (week 4) following fertilization.) |
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Key Events of Human Development during the forth week (week 4) following fertilization. | Key Events of Human Development during the forth week (week 4) following fertilization. | ||
== Week 4 == | |||
[[Week 4]] (Clinical Week 6) | |||
{| class="prettytable" | |||
| <center>'''Day'''</center> | |||
| <center>'''Stage'''</center> | |||
| '''Event''' | |||
|- | |||
| <center>22</center> | |||
| Stage 10 | |||
| [[Image:CST10A.gif]] [[Image:CST10B.gif]] | |||
[http://embryology.med.unsw.edu.au/Notes/ncrest.htm Neural Crest] differentiation at spinal cord level from day 22 until day 26 | |||
[http://embryology.med.unsw.edu.au/Notes/neuron.htm Neural] neural folds begin to fuse near the junction between brain and spinal cord, when [http://embryology.med.unsw.edu.au/Notes/ncrest.htm Neural Crest] cells are arising mainly from the neural ectoderm | |||
[http://embryology.med.unsw.edu.au/Notes/ncrest.htm Neural Crest] trigeminal, facial, and postotic ganglia components visible [http://www.ncbi.nlm.nih.gov/pubmed/17848161 PMID: 17848161] | |||
[http://embryology.med.unsw.edu.au/Notes/ncrest.htm Neural Crest] migration of vagal level neural crest cells begins (7-10 somite stage) | |||
[http://embryology.med.unsw.edu.au/Notes/neuron.htm Brain] rostral neural tube forms 3 primary brain vesicles (week 4) | |||
[http://embryology.med.unsw.edu.au/Notes/respire.htm Respire] Week 4 - laryngotracheal groove forms on floor foregut. | |||
|- | |||
| <center>23</center> | |||
| | |||
| [http://embryology.med.unsw.edu.au/Notes/heart.htm Heart] begins to beat in Humans by day 22-23, first functioning embryonic organ formed. | |||
|- | |||
| <center>24</center> | |||
| Stage 11 | |||
| [[Image:CST11.gif]] | |||
[http://embryology.med.unsw.edu.au/Notes/endocrine8.htm Thyroid] thyroid median endodermal thickening in the floor of pharynx | |||
[http://embryology.med.unsw.edu.au/Notes/neuron.htm Neural] rostral (or cephalic) neuropore closes within a few hours; closure is bidirectional, it takes place from the dorsal and terminal lips and may occur in two areas simultaneously. The two lips, however, behave differently. | |||
Optic ventricle appears | |||
|- | |||
| <center>25</center> | |||
| Stage 12 | |||
| [[Image:CST12.gif]] | |||
[endocrine7.htm Pituitary ]Week 4 hypophysial pouch, Rathke’s pouch, diverticulum from roof | |||
[http://embryology.med.unsw.edu.au/Notes/git7.htm GIT - Liver] septum transversum forming liver stroma and hepatic diverticulum forming hepatic trabeculae [http://www.ncbi.nlm.nih.gov/pubmed/9407542 PMID: 9407542] | |||
[http://embryology.med.unsw.edu.au/Notes/neuron.htm Neural] caudal neuropore takes a day to close (closure is approximately at future somitic pair 31/sacral vertebra 2) | |||
[http://embryology.med.unsw.edu.au/Notes/neuron.htm Neural] secondary neurulation begins | |||
[http://embryology.med.unsw.edu.au/Notes/ncrest.htm Neural Crest] cardiac crest, neural crest from rhombomeres 6 and 7 that migrates to pharyngeal arch 3 and from there the truncus arteriosus [http://www.ncbi.nlm.nih.gov/pubmed/17848161 PMID: 17848161] | |||
[http://embryology.med.unsw.edu.au/Notes/ncrest.htm Neural Crest] vagal neural crest enter the foregut (20-25 somite stage) | |||
|- | |||
| <center>26</center> | |||
| | |||
| | |||
|- | |||
| <center>27</center> | |||
| | |||
| | |||
|- | |||
| <center>28</center> | |||
| Stage 13 | |||
| [[Image:CST13.gif]][http://embryology.med.unsw.edu.au/Notes/neuron.htm Neural] the neural tube is normally completely closed, ventricular system now separated from amniotic fluid. Neural crest at spinal level is segregating, and spinal ganglia are in series with the somites. Spinal cord ventral roots beginning to develop. [http://www.ncbi.nlm.nih.gov/pubmed/3354839 PMID: 3354839] | |||
telencephalon cavity appears | |||
[http://embryology.med.unsw.edu.au/Notes/git7.htm GIT - Liver] epithelial cord proliferation enmeshing stromal capillaries [http://www.ncbi.nlm.nih.gov/pubmed/9407542 PMID: 9407542] | |||
[http://embryology.med.unsw.edu.au/Notes/nose.htm Sense - Smell] Crest comes from the nasal plates[http://www.ncbi.nlm.nih.gov/pubmed/15604533 PMID: 15604533] | |||
[http://embryology.med.unsw.edu.au/Notes/skin.htm Skin] 4 weeks - simple ectoderm epithelium over mesenchyme | |||
[http://embryology.med.unsw.edu.au/Notes/skin.htm Skin] '''1-3 months ectoderm- germinative (basal) cell repeated division of generates stratified epithelium; mesoderm- differentiates into connective tissue and blood vessels | |||
|} | |||
===Carnegie Stages Link=== | |||
[[Carnegie_stage_1|1]] | [[Carnegie_stage_3|3]] | [[Carnegie_stage_7|7]] | [[Carnegie_stage_8|8]] | [[Carnegie_stage_9|9]] | [[Carnegie_stage_10|10]] | [[Carnegie_stage_11|11]] | [[Carnegie_stage_12|12]] | [[Carnegie_stage_13|13]] | [[Carnegie_stage_14|14]] | [[Carnegie_stage_15|15]] | [[Carnegie_stage_16|16]] | [[Carnegie_stage_17|17]] | [[Carnegie_stage_18|18]] | [[Carnegie_stage_19|19]] | [[Carnegie_stage_20|20]] | [[Carnegie_stage_21|21]] | [[Carnegie_stage_22|22]] | [[Carnegie_stage_23|23]] | |||
===Glossary Links=== | |||
[[A|A]] | [[B|B]] | [[C|C]] | [[D|D]] | [[E|E]] | [[F|F]] | [[G|G]] | [[H|H]] | [[I|I]] | [[J|J]] | [[K|K]] | [[L|L]] | [[M|M]] | [[N|N]] | [[O|O]] | [[P|P]] | [[Q|Q]] | [[R|R]] | [[S|S]] | [[T|T]] | [[U|U]] | [[V|V]] | [[W|W]] | [[X|X]] | [[Y|Y]] | [[Z|Z]] | |||
:Dr Mark Hill 2009, '''''UNSW Embryology''''' ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G | |||
[[Category:Human Embryo]] [[Category:Carnegie Stage]] [[Category:Week 5]] |
Revision as of 11:58, 5 August 2009
Key Events of Human Development during the forth week (week 4) following fertilization.
Week 4
Week 4 (Clinical Week 6)
Event | ||
Stage 10 | File:CST10A.gif File:CST10B.gif
Neural Crest differentiation at spinal cord level from day 22 until day 26 Neural neural folds begin to fuse near the junction between brain and spinal cord, when Neural Crest cells are arising mainly from the neural ectoderm Neural Crest trigeminal, facial, and postotic ganglia components visible PMID: 17848161 Neural Crest migration of vagal level neural crest cells begins (7-10 somite stage) Brain rostral neural tube forms 3 primary brain vesicles (week 4) Respire Week 4 - laryngotracheal groove forms on floor foregut. | |
Heart begins to beat in Humans by day 22-23, first functioning embryonic organ formed. | ||
Stage 11 | File:CST11.gif
Thyroid thyroid median endodermal thickening in the floor of pharynx Neural rostral (or cephalic) neuropore closes within a few hours; closure is bidirectional, it takes place from the dorsal and terminal lips and may occur in two areas simultaneously. The two lips, however, behave differently. Optic ventricle appears | |
Stage 12 | File:CST12.gif
[endocrine7.htm Pituitary ]Week 4 hypophysial pouch, Rathke’s pouch, diverticulum from roof GIT - Liver septum transversum forming liver stroma and hepatic diverticulum forming hepatic trabeculae PMID: 9407542 Neural caudal neuropore takes a day to close (closure is approximately at future somitic pair 31/sacral vertebra 2) Neural secondary neurulation begins Neural Crest cardiac crest, neural crest from rhombomeres 6 and 7 that migrates to pharyngeal arch 3 and from there the truncus arteriosus PMID: 17848161 Neural Crest vagal neural crest enter the foregut (20-25 somite stage) | |
Stage 13 | File:CST13.gifNeural the neural tube is normally completely closed, ventricular system now separated from amniotic fluid. Neural crest at spinal level is segregating, and spinal ganglia are in series with the somites. Spinal cord ventral roots beginning to develop. PMID: 3354839
telencephalon cavity appears GIT - Liver epithelial cord proliferation enmeshing stromal capillaries PMID: 9407542 Sense - Smell Crest comes from the nasal platesPMID: 15604533 Skin 4 weeks - simple ectoderm epithelium over mesenchyme Skin 1-3 months ectoderm- germinative (basal) cell repeated division of generates stratified epithelium; mesoderm- differentiates into connective tissue and blood vessels |
Carnegie Stages Link
1 | 3 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23
Glossary Links
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
- Dr Mark Hill 2009, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G