Abnormal Development - Maternal Obesity

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Introduction

African maternal obesity graph
African maternal obesity by country[1]


Environmental Links: Introduction | Low Folic Acid | Iodine Deficiency | Nutrition | Drugs | Australian Drug Categories | USA Drug Categories | Thalidomide | Herbal Drugs | Illegal Drugs | Smoking | Fetal Alcohol Syndrome | TORCH Infections | Viral Infection | Bacterial Infection | Zoonotic Infection | Toxoplasmosis | Malaria | Maternal Diabetes | Maternal Hypertension | Maternal Hyperthermia | Maternal Inflammation | Maternal Obesity | Hypoxia | Biological Toxins | Chemicals | Heavy Metals | Radiation | Prenatal Diagnosis | Neonatal Diagnosis | International Classification of Diseases | Fetal Origins Hypothesis

Some Recent Findings

  • Maternal overweight and obesity in early pregnancy and risk of infant mortality: a population based cohort study in Sweden[2] "Maternal overweight and obesity are associated with increased risks of infant mortality due to increased mortality risk in term births and an increased prevalence of preterm births. Maternal overweight and obesity may be an important preventable risk factor for infant mortality in many countries."
  • Maternal overweight and obesity and risks of severe birth-asphyxia-related complications in term infants: a population-based cohort study in Sweden[3] Maternal overweight and obesity increase risks of pregnancy and delivery complications and neonatal mortality, but the mechanisms are unclear. The objective of the study was to investigate associations between maternal body mass index (BMI) in early pregnancy and severe asphyxia-related outcomes in infants delivered at term (≥37 weeks). ...Risks of severe asphyxia-related outcomes in term infants increase with maternal overweight and obesity. Given the high prevalence of the exposure and the severity of the outcomes studied, the results are of potential public health relevance and should be confirmed in other populations. Prevention of overweight and obesity in women of reproductive age is important to improve perinatal health."
  • Maternal obesity and risk of preterm delivery[4] "Preterm birth is a leading cause of infant mortality, morbidity, and long-term disability, and these risks increase with decreasing gestational age. Obesity increases the risk of preterm delivery, but the associations between overweight and obesity and subtypes of preterm delivery are not clear. ...In Sweden, maternal overweight and obesity during pregnancy were associated with increased risks of preterm delivery, especially extremely preterm delivery. These associations should be assessed in other populations."
More recent papers
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Search term: Maternal Obesity

Andreja Trojner Bregar, Nataša Tul, Vesna Fabjan Vodušek, Ivan Verdenik, Miha Lucovnik, Vid Janša, Isaac Blickstein A dose-response relation exists between different classes of pre-gravid obesity and selected perinatal outcomes. Arch. Gynecol. Obstet.: 2017; PubMed 28646256

Su-Zhen Dong, Ming Zhu Magnetic resonance imaging of fetal persistent left superior vena cava. Sci Rep: 2017, 7(1);4176 PubMed 28646194

Minjie Chen, Xiaoke Wang, Ziying Hu, Huifen Zhou, Yanyi Xu, Lianglin Qiu, Xiaobo Qin, Yuhao Zhang, Zhekang Ying Programming of mouse obesity by maternal exposure to concentrated ambient fine particles. Part Fibre Toxicol: 2017, 14(1);20 PubMed 28645299

Sônia Regina Cabral Madi, Rosa Maria Rahmi Garcia, Vandrea Carla de Souza, Renato Luís Rombaldi, Breno Fauth de Araújo, José Mauro Madi Effect of Obesity on Gestational and Perinatal Outcomes. [Efeito da obesidade sobre os resultados gestacionais e perinatais.] Rev Bras Ginecol Obstet: 2017; PubMed 28645121

Shannon Jette, Julie Maier, Katelyn Esmonde, Cherise Davis Promoting Prenatal Exercise From a Sociocultural and Life-Course Perspective: An "Embodied" Conceptual Framework. Res Q Exerc Sport: 2017;1-13 PubMed 28644729

References

  1. Janet M Wojcicki The double burden household in sub-Saharan Africa: maternal overweight and obesity and childhood undernutrition from the year 2000: results from World Health Organization Data (WHO) and Demographic Health Surveys (DHS). BMC Public Health: 2014, 14(1);1124 PubMed 25361562 | BMC Public Health.
  2. Maternal overweight and obesity in early pregnancy and risk of infant mortality: a population based cohort study in Sweden doi: http://dx.doi.org/10.1136/bmj.g6572 (Published 02 December 2014)
  3. Martina Persson, Stefan Johansson, Eduardo Villamor, Sven Cnattingius Maternal overweight and obesity and risks of severe birth-asphyxia-related complications in term infants: a population-based cohort study in Sweden. PLoS Med.: 2014, 11(5);e1001648 PubMed 24845218
  4. Sven Cnattingius, Eduardo Villamor, Stefan Johansson, Anna-Karin Edstedt Bonamy, Martina Persson, Anna-Karin Wikström, Fredrik Granath Maternal obesity and risk of preterm delivery. JAMA: 2013, 309(22);2362-70 PubMed 23757084

Books

Kathleen M Rasmussen and Ann L Yaktine. Weight Gain During Pregnancy Washington (DC): National Academies Press (US); 2009. ISBN-13: 978-0-309-13113-1 http://www.ncbi.nlm.nih.gov/books/NBK32813

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Cite this page: Hill, M.A. 2017 Embryology Abnormal Development - Maternal Obesity. Retrieved June 26, 2017, from https://embryology.med.unsw.edu.au/embryology/index.php/Abnormal_Development_-_Maternal_Obesity

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© Dr Mark Hill 2017, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G