Worm Development: Difference between revisions
From Embryology
No edit summary |
|||
| Line 7: | Line 7: | ||
:"RNA interference and protein phosphorylation in space environment using the nematode Caenorhabditis elegans (CERISE) is an experiment that addresses two scientific objectives. The first is to evaluate the effect of microgravity on ribonucleic acid (RNA) interference. The second is to study how the space environment effects protein phosphorylation (addition of a phosphate molecule) and signal transduction in the muscle fibers of gene knock-downed Caenorhabditis elegans." | :"RNA interference and protein phosphorylation in space environment using the nematode Caenorhabditis elegans (CERISE) is an experiment that addresses two scientific objectives. The first is to evaluate the effect of microgravity on ribonucleic acid (RNA) interference. The second is to study how the space environment effects protein phosphorylation (addition of a phosphate molecule) and signal transduction in the muscle fibers of gene knock-downed Caenorhabditis elegans." | ||
==Some Recent Findings== | ==Some Recent Findings== | ||
| Line 16: | Line 14: | ||
* '''Small RNAs and temporal control in Caenorhabditis elegans.'''<ref><pubmed>20232378</pubmed></ref> "Developmental timing studies in C. elegans led to the landmark discovery of miRNAs and continue to enhance our understanding of the regulation and activity of these small regulatory molecules. Current views of the heterochronic gene pathway are summarized here, with a focus on the ways in which miRNAs contribute to temporal control and how miRNAs themselves are regulated. Finally, the conservation of heterochronic genes and their functions in timing, as well as their related roles in stem cells and cancer, are highlighted." | * '''Small RNAs and temporal control in Caenorhabditis elegans.'''<ref><pubmed>20232378</pubmed></ref> "Developmental timing studies in C. elegans led to the landmark discovery of miRNAs and continue to enhance our understanding of the regulation and activity of these small regulatory molecules. Current views of the heterochronic gene pathway are summarized here, with a focus on the ways in which miRNAs contribute to temporal control and how miRNAs themselves are regulated. Finally, the conservation of heterochronic genes and their functions in timing, as well as their related roles in stem cells and cancer, are highlighted." | ||
|} | |} | ||
==Adult Anatomy== | |||
[[File:C elegans cartoon.jpg]] | |||
==Adult Hermaphrodite Gonad== | ==Adult Hermaphrodite Gonad== | ||
Revision as of 04:51, 7 November 2010
Introduction
Initially used in the 1960's by Sydney Brenner to study the genetics of development and neurobiology. Early embryological studies of the nematode worm (roundworm) Caenorhabditis elegans (C.Elegans, so called because of its "elegant" curving movement) characterized the fate of each and every cell in the worm through all stages of development. This worm was the first to have its entire genome sequenced and also used recently in space experiments (see below). (More? Worm)
The USA space shuttle Atlantis in November 2009 launched Caenorhabditis elegans into space as part of an experiment to study RNA interference and protein phosphorylation in a space environment.
- "RNA interference and protein phosphorylation in space environment using the nematode Caenorhabditis elegans (CERISE) is an experiment that addresses two scientific objectives. The first is to evaluate the effect of microgravity on ribonucleic acid (RNA) interference. The second is to study how the space environment effects protein phosphorylation (addition of a phosphate molecule) and signal transduction in the muscle fibers of gene knock-downed Caenorhabditis elegans."
Some Recent Findings
|
Adult Anatomy
Adult Hermaphrodite Gonad
|
| Adult hermaphrodite gonad arm[2] - A drawing representation of an adult hermaphrodite gonad arm. The progression of germ cell proliferation and meiosis are indicated by the arrows starting from the distal tip region of the gonad arm. |
References
- ↑ <pubmed>20232378</pubmed>
- ↑ Bickel JS, Chen L, Hayward J, Yeap SL, Alkers AE, et al. (2010) Structural Maintenance of Chromosomes (SMC) Proteins Promote Homolog-Independent Recombination Repair in Meiosis Crucial for Germ Cell Genomic Stability. PLoS Genet 6(7): e1001028. doi:10.1371/journal.pgen.1001028 PLoS Genetics
Reviews
WormBook - a comprehensive, open-access collection of original, peer-reviewed chapters covering topics related to the biology of Caenorhabditis elegans and other nematodes.
Articles
Search Pubmed
July 2010 "c elegans Development" All (5126) Review (898) Free Full Text (2363)
Search Pubmed: Worm Development | Caenorhabditis elegans Development | c elegans Development
External Links
- WormBase
- WormBook open-access collection of chapters covering topics related to the biology of Caenorhabditis elegans (C. elegans) and other nematodes.
- Caenorhabditis Genome Sequencing Projects
- Caenorhabditis elegans WWW Server
| Animal Development: axolotl | bat | cat | chicken | cow | dog | dolphin | echidna | fly | frog | goat | grasshopper | guinea pig | hamster | horse | kangaroo | koala | lizard | medaka | mouse | opossum | pig | platypus | rabbit | rat | salamander | sea squirt | sea urchin | sheep | worm | zebrafish | life cycles | development timetable | development models | K12 |
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, April 30) Embryology Worm Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Worm_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
