Worm Development: Difference between revisions

Revision as of 17:57, 26 July 2010

Introduction

Initially used in the 1960's by Sydney Brenner to study the genetics of development and neurobiology. Early embryological studies of the nematode worm (roundworm) Caenorhabditis elegans (C.Elegans, so called because of its "elegant" curving movement) characterized the fate of each and every cell in the worm through all stages of development. This worm was the first to have its entire genome sequenced and also used recently in space experiments (see below). (More? Worm)

The USA space shuttle Atlantis in November 2009 launched Caenorhabditis elegans into space as part of an experiment to study RNA interference and protein phosphorylation in a space environment.

"RNA interference and protein phosphorylation in space environment using the nematode Caenorhabditis elegans (CERISE) is an experiment that addresses two scientific objectives. The first is to evaluate the effect of microgravity on ribonucleic acid (RNA) interference. The second is to study how the space environment effects protein phosphorylation (addition of a phosphate molecule) and signal transduction in the muscle fibers of gene knock-downed Caenorhabditis elegans."

Some Recent Findings

Small RNAs and temporal control in Caenorhabditis elegans.^[1] "Developmental timing studies in C. elegans led to the landmark discovery of miRNAs and continue to enhance our understanding of the regulation and activity of these small regulatory molecules. Current views of the heterochronic gene pathway are summarized here, with a focus on the ways in which miRNAs contribute to temporal control and how miRNAs themselves are regulated. Finally, the conservation of heterochronic genes and their functions in timing, as well as their related roles in stem cells and cancer, are highlighted."

References

↑ <pubmed>20232378</pubmed>

Search Pubmed

July 2010 "c elegans Development" All (5126) Review (898) Free Full Text (2363)

Search Pubmed: Worm Development | Caenorhabditis elegans Development | c elegans Development

External Links

WormBase
WormBook open-access collection of chapters covering topics related to the biology of Caenorhabditis elegans (C. elegans) and other nematodes.
Caenorhabditis Genome Sequencing Projects
Caenorhabditis elegans WWW Server

Historic Embryology
1897 Pig \| 1900 Chicken \| 1901 Lungfish \| 1904 Sand Lizard \| 1905 Rabbit \| 1906 Deer \| 1907 Tarsiers \| 1908 Human \| 1909 Northern Lapwing \| 1909 South American and African Lungfish \| 1910 Salamander \| 1951 Frog \| Embryology History \| Historic Disclaimer

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link

Cite this page: Hill, M.A. (2024, April 30) Embryology Worm Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Worm_Development

What Links Here?

[1] <pubmed>20232378</pubmed>

[1]

@@ Line 15: / Line 15: @@
 <references/>
-'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Worm+development Worm Development] | [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Caenorhabditis+elegans+development Caenorhabditis elegans Development] | [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=c+elegans+development c elegans Development]
+===Search Pubmed===
+July 2010 "c elegans Development" All (5126) Review (898) Free Full Text (2363)
+'''Search Pubmed:''' [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Worm+development Worm Development] | [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=Caenorhabditis+elegans+development Caenorhabditis elegans Development] | [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=search&term=c+elegans+development c elegans Development]
 ==External Links==