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...n of organ systems established in the embryonic period. In particular, the brain continues to grow and develop, the respiratory system differentiates, the u ...ted and will only be taken into the peritoneal cavity on further body wall growth.

[[File:Placenta term anatomy 01.jpg|800px]] * Human chorionic gonadotrophin (hCG) - like leutenizing hormone, supports corpus l

[[File:Human week 10 fetus 01.jpg|800px]] ...n of organ systems established in the embryonic period. In particular, the brain continues to grow and develop, the respiratory system differentiates, the u

Key Events of Human Development during the fifth week (week 5) following fertilization or clini ...([[Carnegie_stage_15|Stage 15]]) showing a sagittal section upper half of human embryo.]]

[[File:Fetal head section 01.jpg|thumb|300px|alt=Fetal brain showing developing pons|Fetal Head showing developing Pons.]] ...7.jpg|thumb|300px|alt=Right lateral view of adult brain showing Pons|Adult brain showing Pons.]]

* Growth - Fetal Growth Restriction, Developmental Origins of Health and Disease | width=410px|[[File:Fetal limb X-ray-01.jpg|400px]]

The {{third trimester}} is a period of development when the fetus slows in growth in length and begins to increase substantially in weight, this is also the ...These findings indicate that, in the human prefrontal neocortex, dendritic growth in layer V pyramidal neurons occurs rapidly during the third trimester of g

...ntial generation of neurons establishing the layered structure seen in the brain and spinal cord. [[File:Brain stem subdivisions 01.jpg|alt=Brain stem subdivisions|700px]]

...Development|myelencephalon]], that in turn formed from the earlier primary brain vesicle [[Neural - Rhombencephalon Development|rhombencephalon]]. The neura ...ntial generation of neurons establishing the layered structure seen in the brain and spinal cord. Neural development beginnings quite early, therefore also

:''Growth and organ differentiation.'' ...fferentiation of organs and tissues, most importantly this period is about growth both in size and weight.

Human chorionic gonadotropin ({{hCG}}, or human chorionic gonadotrophin) is a placental hormone initially secreted by cells ...}} | [[Week 2]] | {{Trophoblast}} | {{Endocrine placenta}} | {{Ovary}} | [[Human Chorionic Gonadotropin]] | {{Pregnancy test}}

[[File:Stage 22 image 225.jpg|thumb|link=Template:Stage 22 histology gallery|Human Embryo Placental Blood Vessels]] ...larynx|Lisser 1911 - larynx]], [[Paper - The development of the cloaca in human embryos|Pohlman 1911 - cloaca]] and [[Paper - The fifth aortic arch of mamm

[[File:Organoids overview 01.jpg|thumb|alt=Organoids overview|Organoids overview{{#pmid:30219074|PMID3021907 ...demonstrate the utility of SNOs for investigating previously inaccessible human-specific, late-stage cortical development and disease-relevant mechanisms."

[[File:Stage_22_image_217.jpg|thumb|300px|Human embryo developing cortex (week 8, stage 22)]] [[File:Brain_ventricles_and_ganglia_development_03.jpg|thumb|300px|Human cerebrum and underlying ventricular development imaged by [[Magnetic_Resona

| width=365px|<html5media height="400" width="360">File:fetal growth.mp4</html5media> ...Trimester]] and [[Third Trimester]]. Many of the critical measurements of growth are now carried out by [[ultrasound]] and this period ends at [[Birth|birth

| [[File:Puberty growth.jpg|400px]] * The diagram shows the hormonal regulation pathway from the brain to the ovary and subsequent impact on uterine changes during the menstral c

| Human embryo, [[Week 8]], ({{GA}} week 10) [[Carnegie stage 22]] section from the ...ill form the "[[Neural_-_Vascular_Development#Blood-Brain_Barrier|'''blood-brain barrier''']]".

...acodes, lens pit, otocyst, nasal pits moved ventrally, fourth ventricle of brain File:K15818 Stage 20 sagittal 01.jpg|image 1

[[File:WHO report- child growth standards.jpg|right]] ...tones"{{#pmid:16817682|PMID16817682}}, this was released along with new [{{growth charts)).

===The Developing Human: Clinically Oriented Embryology=== | valign=top| [[File:The Developing Human, 10th edn.jpg|90px]]

...ance Imaging]] page with image of [[Magnetic_Resonance_Imaging#Human_Birth|Human Birth]]. Updated [[Gastrointestinal Tract - Abnormalities]] page with Intes ...blastocyst metabolism and hatching information. Added a selected movie of human blastocyst contractions (day 5-6) [[Quicktime_Movie_-_Blastocyst_Contractio

...f the trophoblast. Passive protrusions induced by capillary coiling due to growth of the fetal capillaries within the mature intermediate villi (third trimes | [[File:Placental blood flow 01.jpg|700px]]

...yology|comparative embryology]] and [[K12_Brain_Awareness_Week|comparative brain anatomy]]. ...u.au/community/museum-human-disease/education/teacher-internship Museum of Human Disease - Professional Development Days]

...ral, skull and neck musculoskeletal and endocrine structures. As with many human developmental abnormalities these fall into the three main classes of genet [[File:Head - Treacher Collins Syndrome 01.jpg|thumb|Treacher Collins Syndrome (head lateral view)]]

* {{hearing}} - cochlea continues spiral growth. ...ical sections {{HE}} through regions of the [[Carnegie stage 22|Stage 22]] human embryo from the original serial section set shown below. See also [[Carnegi

...lacodes, lens pit, otocyst,nasal pits moved ventrally, fourth ventricle of brain ...owing retinal pigment, nasolacrimal groove, nasal pit, fourth ventricle of brain, umbilical cord, 1st and 2nd pharyngeal arches, cervical sinus, heart, deve

The human nervous system continues to develop postnatally mostly in glial (white matt ...th higher NMI scores exhibited enhanced connectivity in several functional brain networks, including the default mode network. Analysis of data from a sampl

...circadian fashion and this melatonin can cross both the placenta and blood-brain barrier. In other species, maternal melatonin crosses the placenta into fet ...when calculated from conception date. Other factors such as preeclampsia, growth restriction, and nursery lighting can cause altered rhythm development. The

This animation shows a ventral view of development of the human face from approximately week 5 through to neonate. [[File:Stage14_sem2l.jpg|thumb|Human Embryo Pharyngeal arches (week 50]]

...11weblink}}2012425106 LA05.3 Corpus callosum agenesis] as "the most common brain malformation and is characterized by total or partial absence of the main i ...ifferentiation). The developmental environment can also impact upon neural growth; maternal drugs such as {{alcohol}} and heavy metals such as {{lead}} (mini

...lar_Endothelial_Growth_Factor|Developmental Signals - Vascular Endothelial Growth Factor]] | [[Smooth Muscle Development]] [[File:Adult human cardiovascular system.jpg|thumb|Adult human cardiovascular system]]

...erally as pairs at the same time and form earliest at the cranial (rostral,brain) end of the neural groove and add sequentially at the caudal end. This addi ...ssels is consistent with a variant that might have originated during fetal growth in which the subclavian vein or artery remained included during the process

[[File:Stage_22_image_055.jpg|thumb|Human embryonic hypothalamus ([[Carnegie_stage_22|Stage 22]])]] ...rain (prosenecephalon) primary brain vesicle divides to form two secondary brain vesicles, telencephalon (endbrain, cortex) and diencephalon. The historic d

Recent studies have shown that secondary brain vesicle ({{telencephalon}}) dorsomedial region described as the "cortical h ...ntial generation of neurons establishing the layered structure seen in the brain and spinal cord.

[[File:Brain_ventricles_and_ganglia_development_03.jpg|thumb|Human brain and ventricular development imaged by MRI{{#pmid:20108226|PMID20108226}}]] ...nance imaging}} developmental embryo atlases of several species, including human{{#pmid:20503356|PMID20503356}}, based upon imaging of different age embryos

...ing (MRI) approach to systematically screen adult zebrafish for anatomical growth defects." ...use model of {{cleft palate}} caused by selective deletion of transforming growth factor-β (TGFβ) receptor type 2 in cranial neural crest cells. We identif

[[File:Microlissencephaly MRI-01.jpg|600px]] ...IKV) infection during pregnancy can cause serious birth defects, including brain and eye abnormalities. The clinical importance of detection of ZIKV ribonuc

...) and flexibility (fibrous sutures). The cranial vault (which encloses the brain) bones are formed by {{intramembranous ossification}}. While the bones that ...stly the head to pass through the birth canal and secondly postnatal brain growth. (See also notes on [[Head Development]]) In humans, ossification within th

...embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)|Relative brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)]] ...ntial generation of neurons establishing the layered structure seen in the brain and spinal cord.

{{Header}}[[File:Human-_ventricular_system_cartoon.jpg|300px|right]] [[File:Human-_stage_22_choroid_plexus.jpg|thumb|300px|Human choroid plexus (stage 22)]]

[[File:Placental blood flow 01.jpg|thumb|400px|Scheme of Placental Circulation{{#pmid:29230859|PMID29230859}}] Human placenta classified as '''Haemochorial''' where the chorion comes in direct

[[File:Human ovulation 01.jpg|thumb|300px|Human ovary undergoing ovulation.{{#pmid:18440526|PMID18440526}}]] The {{menstrual cycle}} describes the female human reproductive cycle. This is a cyclic endocrine regulated change in female a

* [https://human-embryology.org Digital Embryology Consortium] * [[Human Embryo SEM|Human SEM]] (eBook)

[[File:Human-retina-01.jpg|thumb|300px|Adult Human Retina histology{{#pmid:12186651|PMID12186651}}]] ...uctures, and muscular tissues. Historically determined that at birth, the human eyeball volume is about 3.25 cc and the estimated weight is about 3.40 gram

...ember 2011 (EST) Updated [[Neural - Cerebellum Development]] with neonatal human cerebellum histology and historic images. ...18, 7 September 2011 (EST) Updated [[Carnegie Stage Comparison]] table for human, mouse and rat to include earlier days/stages.

| <html5media height="480" width="400">File:fetal growth.mp4</html5media> [[Media:fetal growth.mp4|'''Click Here''' to play on mobile device]]

[[File:Implanting human conceptus 01.jpg|300px]] [[File:Gray0032.jpg|300px]] Historic - Semi-diagramatic sagittal section of human uterus containing an embryo. Note the villi locations and the names for dif

...mouse embryo (19 somite) vascular distribution (about [[Carnegie stage 11|Human stage 12]])]] ...Historic image of early human vascular development|Historic image of early human vascular development]]

...is lecture is going to take you briefly through key biological concepts in human development, these will later be explored in more detail through the BGD co [[Media:2019 Foundations Lecture - Introduction to Human Development.pdf|2019 PDF]]

...lacodes, lens pit, otocyst,nasal pits moved ventrally, fourth ventricle of brain [[File:Human stage17 face 01.jpg]]

[[File:Developing human cerebellum 02.jpg|thumb|300px|Developing human cerebellum (1 month postnatal){{#pmid:21858122|PMID21858122}}]] [[File:Mouse Purkinje neuron-01.jpg|thumb|Mouse Purkinje neuron{{#pmid:11724815|PMID11724815}}]]

[[File:Human Stage14 neural02.jpg|thumb|Human Embryo CNS ([[Carnegie stage 14|stage 14]]) showing cranial nerve developme ...historic names. They are paired, and can be mixed (motor/sensory), and the brain equivalent of the spinal cord spinal nerves.

...erally as pairs at the same time and form earliest at the cranial (rostral,brain) end of the neural groove and add sequentially at the caudal end. This addi ...overexpression of Lin28a, an RNA-binding protein that regulates organismal growth and metabolism, in articular chondrocyte progenitor cells upregulated Erk s

Candidates should understand and describe normal and abnormal human development and the principles of implantation, developmental embryology an * [https://human-embryology.org Digital Embryology Consortium]

...or the following: growth retardation; malformations of the heart, eyes, or brain; deafness; and liver, spleen, and bone marrow problems. [[File:USA Measles cases and outbreaks graph 01.jpg|thumb|alt=File:USA Measles cases and outbreaks graph|USA Measles cases and

...erally as pairs at the same time and form earliest at the cranial (rostral,brain) end of the neural groove and add sequentially at the caudal end. This addi ...for vertebrate segmentation and provide a conceptual framework to explain human diseases of the spine, such as congenital scoliosis."

[[File:Stage20-23_limbs_b.jpg|thumb|500px|Human embryonic limb development ([[week 8]])]] ...erally as pairs at the same time and form earliest at the cranial (rostral,brain) end of the neural groove and add sequentially at the caudal end. This addi

...students. Models have been in use for some time in the medical teaching of human development with the original plaster models now replaced by commercial mod ...l processes are conserved across species, just differing in timing, led to growth in [[Animal_Development|"animal models"]]. In particular establishing a sta

[[File:Week10 adrenal.jpg|thumb|300px|Human adrenal gland ([[Second_Trimester|Week 10]])]] ...als. Importantly, fetal endocrine development is required for normal fetal growth and differentiation.

...eased cortisol exposure), genetic susceptibility and accelerated postnatal growth. ...mphasis to that of the early postnatal infant growth. (More? [[Postnatal - Growth Charts]])

| The face is the anatomical feature which is truly unique to each human, though the basis of its general development is identical for all humans an | [[File:The Developing Human, 10th edn.jpg|90px]]

...ill]] ([[User talk:Z8600021|talk]]) 11:12, 19 August 2020 (AEST) Updated {{growth charts}} page with new references. ...age with tables of [[Human_System_Development#Adult_Human_Cell_Types|Adult Human Cell Types]], [[Template:Ectoderm Cell Types table1|Ectoderm Cell Types]],

...surface sensory [[Placodes|placodes]] ('''otic placodes''') that appear in human development during week 4 ({{GA}} week 6) in the head region lying behind t ...phological changes, forming the primitive membranous labyrinth. During the human fetal period this will differentiate into the inner ear components for hear

...constructions of key components of the data herein. At the anatomic level, human and mouse kidney development differ in timing, scale, and global features s ...tically engineered mice and will enhance efforts to describe and interpret brain and spinal cord malformations as causes of mouse embryonic and perinatal le

[[File:Congenital rubella syndrome retinopathy 01.jpg|thumb|300px|alt=Congenital rubella syndrome retinopathy|Retinopathy associa ...s. The initial results of clinical trials of subretinal transplantation of human embryonic stem cell-derived retinal pigment epithelium cells in patients wi

...the body functions (sensory and motor) and consists of 2 main organs: The Brain and Spinal Cord. ...sory information. The midbrain along with the hindbrain together forms the brain-stem which has many important functions such as regulating the cardiac and

...als. Importantly, fetal endocrine development is required for normal fetal growth and differentiation. ...stifiably. EDCs unleash a coordinated attack toward multiple components of human metabolism, including crucial, metabolically-active organs such as hypothal

[[File:Human Stage22 spinal cord02.jpg|thumb|300px|alt=Spinal cord transverse section we ...ntial generation of neurons establishing the layered structure seen in the brain and spinal cord.

This laboratory will look at the third to fourth week of human development (stage 7 onward). We will be using a range of online materials ...s are also shown in the movie [[Embryonic_Development|Carnegie stage human growth through embryonic period]].

[[File:Carnegie stage 13 caudal trunk.jpg|thumb|Human Embryo (Carnegie stage 13) caudal trunk<ref><pubmed>18689800</pubmed>| [htt * '''The Developing Human: Clinically Oriented Embryology''' (8th Edition) by Keith L. Moore and T.V.

[[File:Stage11 sem81.jpg|thumb|Human face (Week 4, Stage 11)]] [[File:Stage14_sem2l.jpg|thumb|Human face (Week 5, Stage 14)]]

=Report upon the Collection of Human Embryos at the Johns Hopkins University= [[File:Franklin Mall 01.jpg|thumb|150px|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]]

[[File:Placental_membranes.jpg|thumb|300px|Human Placental Membranes]] ...00–150 maternal uterine spiral arteries located in the basal plate and the human term placenta is about 9 cm in diameter. There appears to also be differenc

* '''Maternal thyroid hormone''' - required for early stages of brain development ([[#Maternal Thyroid|Maternal Thyroid]] recent studies show bot ...ment. IDD causes goiters and decreases the production of hormones vital to growth and development. (More? {{iodine deficiency}})

[[File:Mouse-morula 01.jpg|150px|Mouse morula]] [[File:Mouse-early blastocyst 01.jpg|150px|Mouse early blastocyst]]

...with production of precursor for placental estrogen production, ovary and brain development, the maturation of the lung and other developing systems. Dehyd ...enal Cortex]] | [[Paper - The development of the adrenal gland in man|1957 Human Adrenal]]

...oor androgens, which occurs across several tissues. Masculinization of the human fetus depends, therefore, on testosterone and androsterone synthesis by bot ...2 activity." [[Developmental Signals - Fibroblast Growth Factor|Fibroblast Growth Factor]]

[[File:Stage11 sem21.jpg|thumb|300px|Human embryo neural crest cells (stage {{CS11}})]] ...provides an anatomical basis to uncover neural circuit assembly in the gut-brain axis."

...ebral hemispheres. It has a very large surface area (largest part of human brain). The cerebral cortex differs from the cerebrum because, the cerebral corte ...an brain''' <ref>Mikayla D (2017). 23. [image] Available at: https://psych-brain-trust.wikispaces.com/Thalamus [Accessed 23 Oct. 2017].</ref> ]]

...at more detailed images could be generated. This current page links to all human and animal ultrasound movies, you can also use the [[:Category:Ultrasound|C ...tion of abnormalities as well as a method of staging (ageing) and checking growth. There are several different standards available{{#pmid:11065037|PMID110650

.... Immunohistochemistry results showed decreased expression of transforming growth factor beta (TGFβ) signaling pathway. Furthermore, the expression of apopt ...learning. The male F1 mice also showed significant deficits in attention, brain monoamine content, and dopamine receptor mRNA expression. Examination of th

:(More? {{nail}} | [[:File:Nail patella syndrome 01.jpg|Image - NPS nails]] | [http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=1 ...then neural tube. The nervous system includes the central nervous system (brain and spinal cord) from the neural tube and the peripheral nervous system (pe

<Flowplayer height="400" width="380" autoplay="true">fetal growth.flv</Flowplayer> ...fferentiation of organs and tissues, most importantly this period is about growth both in size and weight.

[[File:Bacteria - gram-stained vaginal smear 01.jpg|thumb|alt=Bacteria - gram-stained vaginal smear|link=Abnormal_Development_- ...150px|alt=Barr body|link=Molecular_Development_-_X_Inactivation|Barr body (human female neutrophil)]]

This laboratory will look at the first 3 weeks of human development using online resources to study events that lead up to formatio ...l with each cell division. See also [[:File:Human-oocyte_to_blastocyst.jpg|Human oocyte to blastocyst]]

...search for over 30 years. In humans, the homeobox gene family contains 300 human homeobox loci, which we divide into 235 probable functional genes and 65 pr ...tionally and morphologically. During development, extrinsic signals, e.g., growth factors, can activate intrinsic programs, usually orchestrated by networks

Adult human red blood cells normally survive between 90 and 120 days, and are being con ...74,000 skin, kidney and {{yolk sac}} cells, we identify the repertoire of human {{blood}} and {{immune}} cells during development. We infer differentiation

...his paper by [[Embryology History - Franklin Mall|Franklin Mall]] uses his human embryo collection that will eventually form the beginning of the [[Carnegie ...4|The Developmental Alterations in the Vascular System of the Brain of the Human Embryo]]. (1921) [[Book_-_Contributions_to_Embryology#Volume_VIII|Contrib.

...ger gestational age. Future studies should explore if these differences in brain maturation between 37 and 41 weeks of gestational age will persist over tim ...growth in children born SGA does not implicate full catch-up growth of the brain."

...nflammation. Yet, several factors make comparison of the placenta to other human organs difficult. The placenta comprises tissues from two persons, complica ...and umbilical cord of infants treated with hypothermia (HT) due to hypoxic brain injury and follow-up at 12 months of age has been carried out. ...A velamen

...o dog development. Many of these developmental abnormalities are common to human development. [[File:Canine oocyte 01.jpg|thumb|Canine oocyte]]

To grasp the significance of this system in human survival and progression through life it is important to consider where it ...buted to Weber’s research work through which he influenced the view on the human system. Other discoveries that followed Weber’s discoveries about the so

...'' and the late '''Prof. I. Tork''' in the early 1980's. The original 27mm Human embryo microfiche images were developed by '''Dr M. Smith '''and the 6mm Pi ...dited with permission of '''Dr B. Freeman''', from his ''Course Manual for Human Embryology ''(1995). Other staff and former staff who had contributed to th

[[File:Stage16-17-limbs01.jpg|thumb|500px|Human embryonic limb development ([[week 6]])]] [[File:Stage20-23_limbs_b.jpg|thumb|500px|Human embryonic limb development ([[week 8]])]]

...on. Mutations of this gene in mouse (Frodo mouse or Dapper Xenopus) mimic human malformations in the spine, genitourinary system and distal digestive tract [[File:US Dandy-Walker 01.jpg|thumb|150px|alt=Dandy-Walker ultrasound|link=Neural_System_-_Abnormalities#

| Fetal Growth ...''Anatomia uteri humani gravidi tabulis illustrata'' = The anatomy of the human gravid uterus exhibited in figures (1774) [[Embryology History - William Hu

The secreted growth factor {{sonic hedgehog}} ({{SHH}}, {{Shh}}) binds the patched (ptc) recept ..., and may guide future studies on how progenitor cells may be utilized for brain repair."

[[File:Fetal gonad retinoid receptor expression 01.jpg|thumb|Fetal gonad retinoid receptor expression{{#pmid:21674038|PMID21674038 ...the position, size and histological development of the testis in week 8 of human development ([[Carnegie stage 22]], last embryonic week).

...ould be of value to those wanting a better understanding of the process of human haemochorial placentation. ...File:Haemomonochorial human placenta EM01.jpg|thumb|300px|Haemomonochorial human placenta (electron micrograph)]]

[[File:Franklin Mall 01.jpg|thumb|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]] ==On The Frequency of Localized Anomalies in Human Embryos and Infants at Birth==

[[File:Stage11 sem21.jpg|thumb|300px|Human embryo neural crest cells ([[Week 4]], Carnegie stage {{CS11}})]] [[File:Human Stage14 neural02.jpg|thumb|300px|Human embryo neural ([[Week 5]], [[Carnegie stage 14|stage 14]])]]

...bsorbs water (and other compounds) and has endocrine functions. Each adult human kidney typically contains about 750,000 nephrons, though the total number c ...hing 1.jpg|thumb|alt=Human renal branching development between week 5 to 8|Human renal branching development between week 5 to 8.{{#pmid:30192900|PMID301929

...neral observations of how long development takes and the appearance of the human and animal models embryos at different times will not have changed! ...ibutions_to_Embryology_Carnegie_Institution_No.1|Carnegie Institution No.1 Human Embryo In Tubal Pregnancy]]

:(More? {{VACTERL}} | [[Human Abnormal Development|Abnormal Development]] | PMID 21846383) [[File:Bacteria - gram-stained vaginal smear 01.jpg|thumb|150px|alt=Bacteria - gram-stained vaginal smear|link=Abnormal_Develop

Over 1000 genes which make up three percent of the total human genome which encode for ...H. Buxton published a paper containing a series of photographs of a day 25 human embryo in the Journal of Anatomy and Physiology. He noted the thickened rid

[[File:Human Carnegie stage 10-23.jpg|thumb|Carnegie Embryos]] ...on of Embryology]]), the [[#Human Developmental Anatomy Center Collections|Human Developmental Anatomy Center]] holds another 20 historic embryology related

...(Talairach J, Tournoux P (1988). Co-planar stereotaxic atlas of the human brain. Thieme, New York) used in many neural studies. [[File:Talipes equinovarus 01.jpg|thumb|150px|alt=Talipes equinovarus|link=Musculoskeletal_System_-_Limb_Abno

[[File:Human week 10 fetus 10.jpg|thumb|150px|alt=Human week 10 lamina terminals|link=Neural_System_Development#Neuropores|lamina t :(More? {{menstrual cycle}} | [[Menstrual Cycle - Histology]] | [[:File:Human-_menstrual_uterine_endometrium.jpg|Image - Menses uterine endometrium]])

...s visual information from the world around us. Most structures forming the human eye are developed between the embryonic weeks 3 through 10, deriving primar ...embryonic formation and signaling pathways of important structures of the human eye and animal models and finish with an examination of congenital abnormal

...eries of human embryos, now 42 in number, for obviously the embryos of the human species inust be taken as they are obtained, and cannot be selected as they ...alter G. Chase enabled us to employ aid,which contributed very much to the growth of the collection.

[[File:Franklin Mall 01.jpg|thumb|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]] =Cyclopia in the Human Embryo=

[[File:Thalidomide abnormalities 01.jpg|thumb|200px|alt=Thalidomide affected Infant|Thalidomide affected Infant{{#p ...during the first trimester of pregnancy, thalidomide prevented the proper growth of the fetus resulting in horrific birth defects ("thalidomide embryopathy"

...owth, metabolism, electrolyte balance, reproduction and homeostasis of the human body through their release of hormones into the blood stream. Hormones can ...ing page explains the key stages of development of endocrine organs in the human fetus, relevant developmental abnormalities as well as some current researc

...right|Tbx5 3D structure <ref> Pubmed structure (2010) Crystal Structure of Human Tbx5 in the DNA-free Form, https://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdb ...t of certain important regions of human body, mutations of them leads into human gene disorders including Di-George Syndrome and Holt-Oram syndrome. <ref na

...s, opiate drugs can also act through δ- and κ-opioid receptors to modulate growth in a cell-type, region-specific, and developmentally regulated manner. Opio ...lack of information needed to assess the safety of drug treatments during human pregnancy remains a serious public health problem. A more active approach t

[[File:Adherens Junction 01.jpg|thumb|150px|link=Blastocyst Development|Adherens junction cadherin]] ...a plant or animal differs from its mature form. See also [[H#human_embryo|human embryo]].

[[File:Franklin Mall 01.jpg|thumb|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]] ...(_/our». qf [Harp/1., vol. xii), and the other upon the development of the human intestine (His’s Archiv, Supplement Band, 1897).

[[File:Franklin Mall 01.jpg|thumb|300px|Franklin Mall (1911)]] ...Embryology at the Carnegie Institute of Washington. Mall began collecting human embryos while a postgraduate student in Lepzig with [[Embryology_History_-_

[[File:Franklin Mall 01.jpg|thumb|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]] ...rhandl. d. Anatom. Gesellscliaft, 189.5.</ref> whose studies were upon the human umbilical cord. Merkel comes to the conclusion that the white fibers are fo

...for '''S'''haken '''B'''aby '''S'''yndrome, spectrum of neurological (eye, brain, subdural haemorrhage) and other (skeletal) injuries resulting from forcibl [[File:Scarf sign assessment 01.jpg|thumb|150px|alt=Scarf sign|link=Neural Exam - Newborn tone - scarf sign|Sca

{{Human Embryology Manual 1 TOC}} [[File:Franklin Mall 01.jpg|thumb|link=Embryology_History_-_Franklin_Mall|Franklin Mall (1911)]]

...|thumb|150px|alt=MRI brain development|link=Magnetic Resonance Imaging|MRI brain development]] ...ain imaging system that measures electromagnetic changes in regions of the brain that correspond to activity.

===abnormal growth=== ...ment - Fetal Origins Hypothesis|Fetal Origins Hypothesis]] | [[Postnatal - Growth Charts]])

...g|90px|left]] This 1914 paper by James Thomas Wilson (1861-1945) describes human embryos from his own collection at Sydney University. It is not known wheth :'''Links:''' [[Human Embryo Collections]] | [http://sydney.edu.au/medicine/museum/mwmuseum/index

...]] This historic 1998 paper by Mall describes the early development of the human coelom, body cavity. Note "extraembryonic" appears in the paper without a =Development of the Human Coelom=

=Development of the Human Intestine and its Position in the Adult= [[File:Franklin Mall 01.jpg|thumb|150px|alt=Franklin Mall (1911)|link=Embryology History - Franklin Mal

...gs are used clinically to treat premature labor and permit continued fetal growth before parturition. Act on uterine smooth muscle cells to directly block th ...d Exner (1846 – 1926) an Austrian physiologist. Also present in a range of human ovarian tumours.

...ovarian [[F#follicle|follicle]] granulosa layer of some species, including human. Appears as a spherical space staining as an eosinophilic region and contai ...trisomy 21]]) Common name for [[T#trisomy 21|trisomy 21]], the most common human aneuploidy where an extra copy of chromosome 21 is found in the cell genome

...cytokine required for {{blastocyst}} {{implantation}} and also required in human fertility. ...vity 04.jpg|thumb|150px|alt=Stage 23 embryo palate|link=Palate Development|Human Palate (Week 8)]]

...4|The Developmental Alterations in the Vascular System of the Brain of the Human Embryo]]. (1921) [[Book_-_Contributions_to_Embryology#Volume_VIII|Contrib. [[File:Franklin Mall 01.jpg|thumb|alt=Franklin Mall (1911)|link=Embryology History - Franklin Mall|Fran

=A Human Embryo (Mateer) Of The Presomite Period= ...ology_Carnegie_Institution_No.43|'''Paper Links''']]: [[:File:Streeter1920 01.jpg|Fig 1]] | [[:File:Streeter1920 02.jpg|Fig 2]] | [[:File:Streeter1920 03.jpg

...ly because it is so interesting to trace through the dogged attempt of the human mind to cling to a fixed idea. ...rm and endoderm, (3) that the author can confirm Remak’s statement that the brain and spinal cord of Vertebrates are a result of the modification of the sero