Rat Development: Difference between revisions
Line 13: | Line 13: | ||
|-bgcolor="F5FAFF" | |-bgcolor="F5FAFF" | ||
| | | | ||
* '''Generation of germline-competent rat induced pluripotent stem cells''' <ref><pubmed>21789202</pubmed></ref> | |||
* '''Comparison of staging systems for the gastrulation and early neurulation period in rodents'''<ref><pubmed>1440421</pubmed></ref>"Because there is no standard developmental staging system for the early postimplantation period of rodent embryos, investigators must now choose between a variety of systems that differ significantly. We have reviewed many of these staging systems and have summarized the ambiguities within them and the inconsistencies among them. In order to compare systems, we first obtained a consensus of the order of developmental events from the literature, and then attempted to fit existing systems into this order taking into account inconsistencies in terminology and blurred borderlines between stages." | * '''Comparison of staging systems for the gastrulation and early neurulation period in rodents'''<ref><pubmed>1440421</pubmed></ref>"Because there is no standard developmental staging system for the early postimplantation period of rodent embryos, investigators must now choose between a variety of systems that differ significantly. We have reviewed many of these staging systems and have summarized the ambiguities within them and the inconsistencies among them. In order to compare systems, we first obtained a consensus of the order of developmental events from the literature, and then attempted to fit existing systems into this order taking into account inconsistencies in terminology and blurred borderlines between stages." | ||
|} | |} |
Revision as of 07:25, 7 September 2011
Introduction
Rats (taxon - rattus) are readily available as inbred, outbred and mutant strains. They have been generally beaten as a model by their rodent mice brethren, as the molecular tools that became available (stem cells, knockout genes, etc).
Rat embryos do have the advantage of being much larger than mouse embryos and easy to breed. Another advantage of rats is in vision development studies, as that retinal development continues postnatally (most vertebrate neurological systems are difficult to access during periods of development). Rat development is also generally 1 day behind that of mouse. (The table below gives details relating to the staging of rat development). Below this are a list of internet resources relating to the rat.
Some Recent Findings
|
Species Stages Comparison
The table below gives an approximate comparison of human, mouse and rat embryos based upon Carnegie staging.
Species | Stage | |||||||||||||||
Human [3] | Days | 20 | 22 | 24 | 28 | 30 | 33 | 36 | 40 | 42 | 44 | 48 | 52 | 54 | 55 | 58 |
Mouse [4] | Days | 9 | 9.5 | 10 | 10.5 | 11 | 11.5 | 12 | 12.5 | 13 | 13.5 | 14 | 14.5 | 15 | 15.5 | 16 |
Rat [5] | Days | 10.5 | 11 | 11.5 | 12 | 12.5 | 13 | 13.5 | 14 | 14.5 | 15 | 15.5 | 16 | 16.5 | 17 | 17.5 |
- Links: Carnegie Stage Comparison
Adrenal and Gonad Development
Adrenal and gonad steroidogenic factor 1 expression[6]
References
- ↑ <pubmed>21789202</pubmed>
- ↑ <pubmed>1440421</pubmed>
- ↑ <pubmed>400868</pubmed>
- ↑ The House Mouse: Atlas of Mouse Development by Theiler Springer-Verlag, NY (1972, 1989). | online book
- ↑ Witschi, E. (1962) Development: Rat. In: Growth Including Reproduction and Morphological Development. Altman, P. L. , and D. S. Dittmer, ed. Fed. Am. Soc. Exp. Biol., Washington DC, pp. 304-314.
- ↑ <pubmed>14594453</pubmed>| Nucl Recept.
Reviews
Articles
<pubmed>20224168</pubmed> <pubmed>20158911</pubmed> <pubmed>20052412</pubmed>
Search PubMed
Search Pubmed: Rat Development
Additional Images
Historic Images
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- Rat Genome Database RGD <pubmed>17151068</pubmed>
Animal Development: axolotl | bat | cat | chicken | cow | dog | dolphin | echidna | fly | frog | goat | grasshopper | guinea pig | hamster | horse | kangaroo | koala | lizard | medaka | mouse | opossum | pig | platypus | rabbit | rat | salamander | sea squirt | sea urchin | sheep | worm | zebrafish | life cycles | development timetable | development models | K12 |
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, May 4) Embryology Rat Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Rat_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G