Rat Development: Difference between revisions
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File:Rat-hindbrain E11.5.jpg|Rat hindbrain E11.5, down-regulated genes and Pax6 | File:Rat-hindbrain E11.5.jpg|Rat hindbrain E11.5, down-regulated genes and Pax6 | ||
File:Rat_thyroid_system_and_neural_development.jpg|Rat thyroid system and neural development | File:Rat_thyroid_system_and_neural_development.jpg|Rat thyroid system and neural development | ||
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File:Bailey006.jpg|Bailey Fig. 6. Schematic outline of spermatogenesis in the rat | |||
File:Bailey053.jpg|Bailey Fig. 53. Four stages in the cleavage of the ovum of the white rat | |||
File:Bailey056.jpg|Bailey Fig. 56. Sections of blastocysts of the white rat, 5 days after insemination | |||
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Revision as of 07:06, 7 September 2011
Introduction
Rats (taxon- rattus) are readily available as inbred, outbred and mutant strains. They have been generally beaten as a model by their mice brethren, as the molecular tools that became available (stem cells, knockout genes, etc).
Rat embryos do have the advantage of being much larger than mouse embryos and easy to breed. Another advantage of rats is in vision development studies, as that retinal development continues postnatally (most vertebrate neurological systems are difficult to access during periods of development). Rat development is also generally 1 day behind that of mouse. (The table below gives details relating to the staging of rat development). Below this are a list of internet resources relating to the rat.
Some Recent Findings
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Species Stages Comparison
The table below gives an approximate comparison of human, mouse and rat embryos based upon Carnegie staging.
Species | Stage | |||||||||||||||
Human [2] | Days | 20 | 22 | 24 | 28 | 30 | 33 | 36 | 40 | 42 | 44 | 48 | 52 | 54 | 55 | 58 |
Mouse [3] | Days | 9 | 9.5 | 10 | 10.5 | 11 | 11.5 | 12 | 12.5 | 13 | 13.5 | 14 | 14.5 | 15 | 15.5 | 16 |
Rat [4] | Days | 10.5 | 11 | 11.5 | 12 | 12.5 | 13 | 13.5 | 14 | 14.5 | 15 | 15.5 | 16 | 16.5 | 17 | 17.5 |
- Links: Carnegie Stage Comparison
Adrenal and Gonad Development
Adrenal and gonad steroidogenic factor 1 expression[5]
References
- ↑ <pubmed>1440421</pubmed>
- ↑ <pubmed>400868</pubmed>
- ↑ The House Mouse: Atlas of Mouse Development by Theiler Springer-Verlag, NY (1972, 1989). | online book
- ↑ Witschi, E. (1962) Development: Rat. In: Growth Including Reproduction and Morphological Development. Altman, P. L. , and D. S. Dittmer, ed. Fed. Am. Soc. Exp. Biol., Washington DC, pp. 304-314.
- ↑ <pubmed>14594453</pubmed>| Nucl Recept.
Search Pubmed: Rat Development
Additional Images
Historic Images
External Links
- Rat Genome Database RGD <pubmed>17151068</pubmed>
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Cite this page: Hill, M.A. (2024, May 7) Embryology Rat Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Rat_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G