Rat Development: Difference between revisions
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==Some Recent Findings== | ==Some Recent Findings== | ||
Generation and characterization of a Tet-On (rtTA-M2) transgenic rat. | Generation and characterization of a Tet-On (rtTA-M2) transgenic rat. Sheng Y, Lin CC, Yue J, Sukhwani M, Shuttleworth JJ, Chu T, Orwig KE. BMC Dev Biol. 2010 Feb 16;10:17. [http://www.ncbi.nlm.nih.gov/pubmed/20158911 PMID: 20158911] | ||
Sheng Y, Lin CC, Yue J, Sukhwani M, Shuttleworth JJ, Chu T, Orwig KE. | |||
BMC Dev Biol. 2010 Feb 16;10:17. | |||
PMID: 20158911 | |||
:"This conditional expression rat model may have application for transgenic overexpression or knockdown studies of gene function in development, disease and gene therapy." | |||
==References== | ==References== |
Revision as of 07:06, 29 March 2010
Introduction
Rats (taxon- rattus) are readily available as inbred, outbred and mutant strains. They have been generally beaten as a model by their mice brethren, as the molecular tools that became available (stem cells, knockout genes, etc).
Rat embryos do have the advantage of being much larger than mouse embryos and easy to breed. Another advantage of rats is in vision development studies, as that retinal development continues postnatally (most vertebrate neurological systems are difficult to access during periods of development). Rat development is also generally 1 day behind that of mouse. (The table below gives details relating to the staging of rat development). Below this are a list of internet resources relating to the rat. This model organism has only a relatively small amount (0.2 %) of the total rat genome sequenced. (More? see rat genome)
Links: original Rat page
Some Recent Findings
Generation and characterization of a Tet-On (rtTA-M2) transgenic rat. Sheng Y, Lin CC, Yue J, Sukhwani M, Shuttleworth JJ, Chu T, Orwig KE. BMC Dev Biol. 2010 Feb 16;10:17. PMID: 20158911
- "This conditional expression rat model may have application for transgenic overexpression or knockdown studies of gene function in development, disease and gene therapy."
References
Search Pubmed: Rat Development
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Cite this page: Hill, M.A. (2024, May 2) Embryology Rat Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Rat_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G