Neural - Tectum Development
Introduction
Neural development is one of the earliest systems to begin and the last to be completed after birth. This development generates the most complex structure within the embryo and the long time period of development means in utero insult during pregnancy may have consequences to development of the nervous system.
Differences between birds and mammals:
- both - have retinal axons projecting topographically to targets in the brain.
- birds - the visual fibers from the entire retina decussate at the optic chiasm.
- mammals - some axons from the temporal retina diverge at the midline to project ipsilaterally.
Neural development beginnings quite early, therefore also look at notes covering Week 3- neural tube and Week 4-early nervous system. Development of the neural crest and sensory systems (hearing/vision/smell) are only introduced in these notes and are covered in other notes sections.
Some Recent Findings
|
Recent References | References
Developmental Signaling Model
Model of interaction of Meis2, Pax3 and Pax7 during dorsal midbrain development. [3]
Development Overview
Neuralation begins at the trilaminar embryo with formation of the notochord and somites, both of which underly the ectoderm and do not contribute to the nervous system, but are involved with patterning its initial formation. The central portion of the ectoderm then forms the neural plate that folds to form the neural tube, that will eventually form the entire central nervous system.
- Early developmental sequence: Epiblast - Ectoderm - Neural Plate - Neural groove and Neural Crest - Neural Tube and Neural Crest
Neural Tube | Primary Vesicles | Secondary Vesicles | Adult Structures |
---|---|---|---|
week 3 | week 4 | week 5 | adult |
prosencephalon (forebrain) | telencephalon | Rhinencephalon, Amygdala, hippocampus, cerebrum (cortex), hypothalamus, pituitary | Basal Ganglia, lateral ventricles | |
diencephalon | epithalamus, thalamus, Subthalamus, pineal, posterior commissure, pretectum, third ventricle | ||
mesencephalon (midbrain) | mesencephalon | tectum, Cerebral peduncle, cerebral aqueduct, pons | |
rhombencephalon (hindbrain) | metencephalon | cerebellum | |
myelencephalon | medulla oblongata, isthmus | ||
spinal cord, pyramidal decussation, central canal |
Early Brain Vesicles
Primary Vesicles
Secondary Vesicles
References
- ↑ <pubmed>22390724</pubmed>| BMC Dev Biol.
- ↑ <pubmed>20558153</pubmed>
- ↑ <pubmed>22390724</pubmed>| BMC Dev Biol.
Reviews
<pubmed>19206138</pubmed>
Articles
<pubmed>18230116</pubmed>
Search PubMed
Search Pubmed: Tectum Embryology | Tectum Development
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Cite this page: Hill, M.A. (2024, June 10) Embryology Neural - Tectum Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_-_Tectum_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G