Neural - Myelencephalon Development
|Embryology - 15 Oct 2018 Expand to Translate|
|Google Translate - select your language from the list shown below (this will open a new external page)|
العربية | català | 中文 | 中國傳統的 | français | Deutsche | עִברִית | हिंदी | bahasa Indonesia | italiano | 日本語 | 한국어 | မြန်မာ | Pilipino | Polskie | português | ਪੰਜਾਬੀ ਦੇ | Română | русский | Español | Swahili | Svensk | ไทย | Türkçe | اردو | ייִדיש | Tiếng Việt These external translations are automated and may not be accurate. (More? About Translations)
Neural development is one of the earliest systems to begin and the last to be completed after birth. This development generates the most complex structure within the embryo and the long time period of development means in utero insult during pregnancy may have consequences to development of the nervous system.
The early central nervous system begins as a simple neural plate that folds to form a groove then tube, open initially at each end. Failure of these opening to close contributes a major class of neural abnormalities (neural tube defects).
Within the neural tube stem cells generate the 2 major classes of cells that make the majority of the nervous system : neurons and glia. Both these classes of cells differentiate into many different types generated with highly specialized functions and shapes. This section covers the establishment of neural populations, the inductive influences of surrounding tissues and the sequential generation of neurons establishing the layered structure seen in the brain and spinal cord.
- Neural development beginnings quite early, therefore also look at notes covering Week 3- neural tube and Week 4-early nervous system.
- Development of the neural crest and sensory systems (hearing/vision/smell) are only introduced in these notes and are covered in other notes sections.
- Neural Parts: neural | prosencephalon | telencephalon cerebrum | amygdala | hippocampus | basal ganglia | lateral ventricles | diencephalon | Epithalamus | thalamus | hypothalamus | pituitary | pineal | third ventricle | mesencephalon | tectum | cerebral aqueduct | rhombencephalon | metencephalon | pons | cerebellum | myelencephalon | medulla oblongata | spinal cord | neural vascular | meninges | Category:Neural
Some Recent Findings
|More recent papers|
This table shows an automated computer PubMed search using the listed sub-heading term.
References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability.
Tomasz Krzywkowski, Mats Nilsson Padlock Probes to Detect Single Nucleotide Polymorphisms. Methods Mol. Biol.: 2018, 1649;209-229 PubMed 29130200
A-M Kiviranta, C Rusbridge, O Laitinen-Vapaavuori, A Hielm-Björkman, A K Lappalainen, S P Knowler, T S Jokinen Syringomyelia and Craniocervical Junction Abnormalities in Chihuahuas. J. Vet. Intern. Med.: 2017, 31(6);1771-1781 PubMed 28892202
J Díaz-Delgado, K R Groch, M W Wiegand, E R Secchi, R Réssio, F C C Natália, J L Catão-Dias Choroid Plexus Cyst in a Neonatal Burmeister's Porpoise (Phocoena spinipinnis). J. Comp. Pathol.: 2017, 157(1);51-56 PubMed 28735671
Serpil Kurtcan, Alpay Alkan, Huseyin Yetis, Umit Tuzun, Ayse Aralasmak, Huseyin Toprak, Huseyin Ozdemir Diffusion tensor imaging findings of the brainstem in subjects with tonsillar ectopia. Acta Neurol Belg: 2018, 118(1);39-45 PubMed 28516323
Bai-Hong Tan, Chun-Yan Guo, Tian-Qing Xiong, Ling-Meng Chen, Yan-Chao Li The unique organization of filamentous actin in the medullary canal of the medulla oblongata. Tissue Cell: 2017; PubMed 28187870
Neuralation begins at the trilaminar embryo with formation of the notochord and somites, both of which underly the ectoderm and do not contribute to the nervous system, but are involved with patterning its initial formation. The central portion of the ectoderm then forms the neural plate that folds to form the neural tube, that will eventually form the entire central nervous system.
- Early developmental sequence: Epiblast - Ectoderm - Neural Plate - Neural groove and Neural Crest - Neural Tube and Neural Crest
|Neural Tube||Primary Vesicles||Secondary Vesicles||Adult Structures|
|week 3||week 4||week 5||adult|
|Prosencephalon||Telencephalon||Rhinencephalon, Amygdala, Hippocampus, Cerebrum (Cortex), Hypothalamus, Pituitary | Basal Ganglia, lateral ventricles|
|Diencephalon||Epithalamus, Thalamus, Subthalamus, Pineal, third ventricle|
|Mesencephalon||Mesencephalon||Tectum, Cerebral peduncle, Pretectum, cerebral aqueduct|
Early Brain Vesicles
- Harukazu Nakamura, Tatsuya Sato, Asuka Suzuki-Hirano Isthmus organizer for mesencephalon and metencephalon. Dev. Growth Differ.: 2008, 50 Suppl 1;S113-8 PubMed 18494704
- Eiji Matsunaga, Tatsuya Katahira, Harukazu Nakamura Role of Lmx1b and Wnt1 in mesencephalon and metencephalon development. Development: 2002, 129(22);5269-77 PubMed 12399317
- M Wassef, A L Joyner Early mesencephalon/metencephalon patterning and development of the cerebellum. Perspect Dev Neurobiol: 1997, 5(1);3-16 PubMed 9509514
Nicholas D E Greene, Andrew J Copp Development of the vertebrate central nervous system: formation of the neural tube. Prenat. Diagn.: 2009, 29(4);303-11 PubMed 19206138
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2018, October 15) Embryology Neural - Myelencephalon Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Neural_-_Myelencephalon_Development
- © Dr Mark Hill 2018, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G