User:Z5014803: Difference between revisions
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[[File:Development_of_mouse_embryo_in_early_stages.png|400px|thumb|centre|Live imaging of the whole mouse embryo at E6 (A to D) and E5.5. (E to H)<ref><pubmed>23861733</pubmed></ref>]] | [[File:Development_of_mouse_embryo_in_early_stages.png|400px|thumb|centre|Live imaging of the whole mouse embryo at E6 (A to D) and E5.5. (E to H)<ref><pubmed>23861733</pubmed></ref>]] | ||
===References=== |
Revision as of 22:04, 18 August 2016
Student Information (expand to read) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Individual Assessments | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Please leave this template on top of your student page as I will add your assessment items here. Beginning your online work - Working Online in this course
Click here to email Dr Mark Hill | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lab 1 Assessment - Researching a Topic | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
In the lab I showed you how to find the PubMed reference database and search it using a topic word. Lab 1 assessment will be for you to use this to find a research reference on "fertilization" and write a brief summary of the main finding of the paper.
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Lab 2 Assessment - Uploading an Image | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
OK you are now in a group
Initially the topic can be as specific or as broad as you want. Chicken embryo E-cad and P-cad gastrulation[1] References
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Lab 4 Assessment - GIT Quiz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ANAT2341 Quiz Example | Category:Quiz | ANAT2341 Student 2015 Quiz Questions | Design 4 quiz questions based upon gastrointestinal tract. Add the quiz to your own page under Lab 4 assessment and provide a sub-sub-heading on the topic of the quiz. An example is shown below (open this page in view code or edit mode). Note that it is not just how you ask the question, but also how you explain the correct answer. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lab 5 Assessment - Course Review | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Complete the course review questionnaire and add the fact you have completed to your student page. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lab 6 Assessment - Cleft Lip and Palate | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Lab 7 Assessment - Muscular Dystrophy | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Lab 8 Assessment - Quiz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A brief quiz was held in the practical class on urogenital development. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lab 9 Assessment - Peer Assessment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Lab 10 Assessment - Stem Cells | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
As part of the assessment for this course, you will give a 15 minutes journal club presentation in Lab 10. For this you will in your current student group discuss a recent (published after 2011) original research article (not a review!) on stem cell biology or technology.
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Lab 11 Assessment - Heart Development | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Read the following recent review article on heart repair and from the reference list identify a cited research article and write a brief summary of the paper's main findings. Then describe how the original research result was used in the review article.
<pubmed>26932668</pubmed>Development | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Lab Attendance
Z5014803 (talk) 18:29, 5 August 2016 (AEST)
Z5014803 (talk) 14:40, 12 August 2016 (AEST)
Belbin Team Roles
In my previous courses, I was introduced to the Bebin model team roles as a way to identify myself in a team scenario. I definitely see myself as a "Shaper" since I am driven to try and complete the task at hand as soon as possible to ensure sufficient time for the editing process and the refining of the task. I also agree that I motivate other team members to progress through the task at a efficient pace such that the group does not lose momentum. I am also a person who is not afraid to speak my mind and thus will contest other viewpoints in order to spark a discussion. I identify myself as a very dynamic person in the way that I act according to the different predicaments I'm in and this results in numerous ways of efficiently solving any problems. Although I identify myself as a Shape I do not agree that i can become aggressive or bad humoured as I see some traits of a Co-ordinator in me. I have a very mature approach and recognise that each individual has a different way of attacking a problem and have learnt to appreciate others.
Lecture 1: Fertilisation
I have always been fond of the details surrounding fertilisation as it seems like a very interesting topic. It is more than just a sperm and egg cell coming together. The first lecture on fertilisation highlighted the various processes that need to occur in order to form a zygote, from gametogenesis to fertilisation and then forming the zygote. In my first year studies I learnt that there is a mechanism to prevent multiple sperm cells to enter the ovum but wasnt familiar with the process. The most interesting aspect of this lecture was precisely the process from fertilisation to the prevention of polyspermy. I was intrigued by how sperm cells are attracted to the oocyte which was through the ZP2 protein and only the nucleus of the spermatozoa enters the cell membranes. I was also interested in how membrane fusion will result in oocyte processes that will prevent polyspermy through the elevation of intracellular calcium levels. I had minimal knowledge of this topic but the lecture really made me want to learn about this process in a lot more detail.
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Referencing
PMID 27486480
Assessment 1
<pubmed>27486266</pubmed>
In order for fertilization to occur spermatozoa must be activated in a process known as 'sperm capacitation'. The primary research article "Seminal vesicle proteins SVS3 and SVS4 facilitate SVS2 effect on sperm capacitation" by Araki et al (2016) investigate the role of seminal vesicle secretion and how they inhibit the activation of spermatozoa and how they reduce the fertility of the capacitated spermatozoa (decapacitation). In previous studies it has already been shown that SVS2 acts as a capacitation inhibitor and a decapacitation factor and Araki et al (2016) build up on this pre existent knowledge about SVSs other than SVS2. The investigation utilised CD-1 mice, in particular female mice, to show the effects of SVS3 and SVS4 on sperm cells in the female reproductive tract.
Levels of SVS3 and SVS4 were measured in each part of the female reproductive tract such as the copulaatory plug, vagina, oviduct and uterine region near the vagina and oviduct 1.5 hours post copulation. By using anti SVS3 antibody there were clear indications as to the specific roles of SVS3. Results showed that there were no SVS3 proteins in any of the aforementioned parts of the reproductive tract and thus the protein alone had no effects on sperm capacitation. In saying that, SVS3 proteins did show that they had the ability to potentiate the effects of SVS2. Similarly anti SVS4 antibody was utilised to provide insight into the function of this particular protein. Contrary to the findings for SVS3, SVS4 was detected in the uterus but not in any other part of the tract. This suggests that SVS4 has similar activity to that of SVS2 in a way that both the proteins enter the uterus. Thus, SVS4 acts as a capacitation inhibitor similar to SVS2 but results indicated that it does not have the decapacitation effect like SVS2.
Mark Hill 18 August 2016 - You have added the citation correctly and written a good summary of this very recent article, still only available in the pre-published submitted format, findings. One thing, you must always include the full term in your summary (even if it appears in the paper title) before you begin to use the acronym. "SVS" (seminal vesicle protein secretion) could and may mean different things in different contexts.
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Assessment 5/5 |
Assessment 2
References
- ↑ <pubmed>23861733</pubmed>