Developmental Signals - Hippo: Difference between revisions
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| active Hippo signaling | | active Hippo signaling |
Revision as of 11:34, 10 June 2015
Embryology - 19 Jun 2024 Expand to Translate |
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Introduction
The Hippo pathway, first identified in Drosophila, controls organ size by regulating cell proliferation (inhibition) and apoptosis (induction). In contrast, the TOR signalling pathway regulates organ size by stimulating cell growth, thus increasing cell size.
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Factor Links: AMH | hCG | BMP | sonic hedgehog | bHLH | HOX | FGF | FOX | Hippo | LIM | Nanog | NGF | Nodal | Notch | PAX | retinoic acid | SIX | Slit2/Robo1 | SOX | TBX | TGF-beta | VEGF | WNT | Category:Molecular |
Some Recent Findings
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More recent papers |
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This table allows an automated computer search of the external PubMed database using the listed "Search term" text link.
More? References | Discussion Page | Journal Searches | 2019 References | 2020 References Search term: Embryo Hippo | Images <pubmed limit=5>Embryo Hippo</pubmed> |
Early Development
Blastocyst
Mouse blastocyst (32 cell stage) | |
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phosphorylation of angiomotin at adherens junctions | cell polarization sequesters Amot from basolateral adherens junctions |
active Hippo signaling | inactive Hippo signaling |
inner cells | outer cells |
inner cell mass (ICM) fate | trophectoderm (TE) fate |
(Table data refecence[2])
Organ Expression
Endoderm
Fetal Gonad
Neural
References
Reviews
<pubmed>26032720</pubmed> <pubmed>22575479</pubmed> <pubmed>21808241</pubmed> <pubmed>19517570</pubmed>
Articles
<pubmed>25628125</pubmed> <pubmed>25918243</pubmed> <pubmed></pubmed> <pubmed></pubmed>
Search Pubmed
Search Bookshelf Hippo
Search Pubmed Now: Hippo
Glossary Links
- Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link
Cite this page: Hill, M.A. (2024, June 19) Embryology Developmental Signals - Hippo. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Developmental_Signals_-_Hippo
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G