Dog Development - Abnormalities

Introduction

Adult dog

The domestic dog (Canis lupus familiaris) has been derived from an ancestoral wolf and now consists of a breed family of more than 300 worldwide, with extensive variations in morphology (size, shape and weight). The modern dog breeds show high phenotypic diversity and are thought to have arisen from this first population bottleneck associated with wolf domestication (7,000–50,000 generations ago) and a second from more recent intensive selection to create the breed (50–100 generations ago).

The average canine gestation period from ovulation to birth (parturition) is approximately 64 days and there have been identified about 400 congenital disorders relating to dog development.

Many of these developmental abnormalities are common to human development. The list below links to information on the Online Mendelian Inheritance in Animals.

Links: Online Mendelian Inheritance in Animals | Search for Canis familiaris

Dog Abnormalities List

• Hyperekplexia in dog

• Episodic falling in dog

• Dry eye curly coat syndrome in dog

• Coat colour, melanistic mask in dog

• Anal furunculosis in dog

• Ichthyosis, Golden Retriever in dog

• Deficiency of cytosolic arylamine N-acetylation in dog

• Muscular hypertrophy in dog

• Glycogen storage disease IIIa in dog

• PRA-rod-cone dystrophy type 4 in dog

• Neuronal ceroid lipofuscinosis, 6 in dog

• Severe combined immunodeficiency disease, autosomal, T cell-negative, B cell-negative, NK cell-posit in dog

• Leukemia, chronic monocytic in dog

• Progressive retinal atrophy, SLC4A3 in dog

• Persistent right aortic arch, with subclavian artery and ligamentum arteriosum in dog

• Bleeding disorder due to P2RY12 defect in dog

• Sebaceous adenitis in dog

• Periodic Fever Syndrome in dog

• Niemann-Pick disease, type C in dog

• Retinopathy, multifocal, 3 in dog

• Retinopathy, multifocal, 2 in dog

• Neuronal ceroid lipofuscinosis, adult-onset, Tibetan Terrier in dog

• Chylothorax in dog

• Brachycephaly in dog

• Dyskinesia, paroxysmal in dog

• Ciliary dyskinesia, primary in dog

• Eye colour in dog

• Coat colour, cream dilution in dog

• Coat colour, agouti in dog

• Heterochromia iridis in dog

• Curly coat in dog

• Furnishings (moustache and eyebrows) in dog

• Compulsive disorder in dog

• Priapism in dog

• Encephalomyelopathy and polyneuropathy in dog

• Leukocyte adhesion deficiency, 3 in dog

• Gallbladder mucoceles in dog

• Oculoskeletal dysplasia, 2 in dog

• Oculoskeletal dysplasia in dog

• Progressive retinal atrophy, Schapendoes in dog

• Cone-rod dystrophy 3 in dog

• persistent hyaloid remnants in dog

• Progressive retinal atrophy, X-linked, 2 in dog

• Progressive retinal atrophy, X-linked, 3 in dog

• Retinal dystrophy in dog

• Gastrointestinal stromal tumor in dog

• Colorectal hamartomatous polyposis and ganglioneuromatosis in dog

• Acral mutilation syndrome in dog

• Hypomyelination of the central nervous system in dog

• Chronic myelogenous leukemia in dog

• Transitional cell carcinoma in dog

• Musladin-Lueke syndrome in dog

• Myotubular myopathy 1 in dog

• Incomplete ossification of the humeral condyle in dog

• Neuronal ceroid lipofuscinosis, 8 in dog

• Neuronal ceroid lipofuscinosis, 5 in dog

• Neuronal ceroid lipofuscinosis, 10 in dog

• Neuronal ceroid lipofuscinosis, 1 in dog

• Neuronal ceroid lipofuscinosis, 4A in dog

• Anal sac gland carcinoma in dog

• Aggression in dog

• Improper coat in dog

• Coat colour, grizzle in dog

• Myopia in dog

• Vitamin D-deficiency rickets, type I in dog

• Vitamin D-deficiency rickets, type II in dog

• Osteogenesis imperfecta Dachshund in dog

• Hepatitis, copper-associated chronic in dog

• Rupture of the cranial cruciate ligament in dog

• Persistent truncus arteriosus in dog

• Hair length in dog

• Neuronal ceroid lipofuscinosis, 2 in dog

• Neonatal encephalopathy with seizures in dog

• Necrotizing meningoencephalitis in dog

• Multiple system degeneration in dog

• Ectodermal dysplasia in dog

• Sensory ataxic neuropathy in dog

• Exercise-induced collapse in dog

• Retinitis pigmentosa in dog

• Stereotypes in dog

• Cone-rod dystrophy 2 in dog

• Coat colour, harlequin in dog

• Spondyloepiphyseal dysplasia, congential type in dog

• Retinopathy, multifocal in dog

• Osteosarcoma in dog

• Knobbed acrosome in dog

• Cone-rod dystrophy 1 in dog

• Trapped Neutrophil Syndrome in dog

• Gangliosidosis, GM2, GM2A deficiency in dog

• Patent ductus venosus in dog

• Retinal dysplasia and persistent primary vitreous in dog

• Pulmonary adenomatosis in dog

• Aortic aneurysm, familial thoracic in dog

• Cricopharyngeal dysfunction in dog

• Coat colour, dominant black in dog

• Hyperkeratosis, epidermolytic in dog

• Mucopolysaccharidosis IIIB in dog

• Patent urachus in dog

• Anodontia in dog

• Lymphoproliferative disease in dog

• Pyruvate dehydrogenase deficiency in dog

• Coat colour, white spotting in dog

• Metabolizer of a congitive enhancer in dog

• Pancreatitis, hereditary in dog

• Multidrug resistance 1 in dog

• Hemimelia in dog

• Spherocytosis in dog

• Myopathy, centronuclear in dog

• Imperforate anus with rectovaginal fistula in dog

• Nasal parakeratosis in dog

• L-2-hydroxyglutaricacidemia in dog

• Acrochordonous plaque in dog

• Follicular dysplasia and interface dermatitis in dog

• Achalasia of the oesophagus, congenital in dog

• Achromatopsia-3 in dog

• Cerebellar degeneration in dog

• Ataxia, progressive, with head tremor and seizures in dog

• Vitamin-K-dependent blood coagulation factors deficiency in dog

• Dysplasia epiphysealis hememelica in dog

• Nephritis, autosomal recessive in dog

• Coat colour, dominant white in dog

• Coat colour, brown in dog

• Platelet receptor for factor X, deficiency of in dog

• Urolith, KMgP in dog

• Fibrodysplasia ossificans in dog

• Severe combined immunodeficiency disease, autosomal in dog

• PRA-autosomal dominant in dog

• Tricuspid valve dysplasia in dog

• Leucodystrophy in dog

• Von Willebrand disease II in dog

• Hypocatalasia in dog

• Epistaxis in dog

• Renal cystadenocarcinoma and nodular dermatofibrosis in dog

• Eclampsia in dog

• Linear IgA disease in dog

• Hyperkeratosis, palmoplantar in dog

• Arnold-Chiari malformation in dog

• Protein-losing nephropathy in dog

• Protein-losing enteropathy in dog

• Retinal dysplasia in dog

• Necrotising encephalopathy, subacute, of Leigh in dog

• Atresia intestinal in dog

• Potassium transport in dog

• Nephritis, X-linked dominant in dog

• Elliptocytosis in dog

• Epidermolysis bullosa in dog

• Mucopolysaccharidosis II in dog

• Neoplasia, mammary gland in dog

• Motor neuron disease, lower in dog

• Acromegaly in dog

• PRA-rod-cone dystrophy type 3 in dog

• Photoreceptor dysplasia in dog

• Ichthyosis in dog

• Mucopolysaccharidosis IIIA in dog

• Atherosclerosis in dog

• Disorder of cornification in dog

• Neuronal vacuolar disorder in dog

• Aplasia segmentalis ductus wolffii in dog

• Rod-cone degeneration, progressive in dog

• Retinal degeneration, early in dog

• Dwarfism, hypochondroplastic in dog

• Blood group system Rh in dog

• Polycystic kidney disease in dog

• Anhidrotic ectodermal dysplasia in dog

• Hypercholesterolaemia in dog

• Renal disease in dog

• Polyneuropathy in dog

• Hypoparathyroidism in dog

• Arthritis in dog

• Exophthalmos with strabismus in dog

• Tail abnormalities in dog

• Scoliosis in dog

• Keratitis in dog

• Motor neuron disease in dog

• Mitochondrial myopathy in dog

• Xanthinuria in dog

• Immunoglobulin G deficiency in dog

• Spongiform encephalopathy in dog

• Neuronopathy, progressive in dog

• Polioencephalomyelopathy in dog

• Otitis media, susceptibility to in dog

• Wilms tumour in dog

• Heterochromia in dog

• Brachygnathia in dog

• Hydrocephalus, internal in dog

• Intussusception in dog

• Comedo syndrome in dog

• Lipidosis in dog

• Hydromelia in dog

• PRA-rod-cone dystrophy type 2 in dog

• Gluten-sensitive enteropathy in dog

• Spina bifida occulta in dog

• Renal hypoplasia, bilateral in dog

• Genetic maps in dog

• Syringomyelia in dog

• Encephalomyelopathy in dog

• Hernia, scrotal in dog

• Ectrodactyly in dog

• Chronic valvular disease in dog

• Atopy in dog

• Hypothyroidism, primary in dog

• Lysosomal storage disease in dog

• Oligodontia in dog

• Polycythemia in dog

• Hyperphosphatasaemia in dog

• Syndactyly in dog

• Coeliac sprue in dog

• Pemphigus in dog

• Urolith, urate in dog

• Coat colour, extension in dog

• Menkes syndrome in dog

• Haemophagocytic syndrome in dog

• Polymelia in dog

• Goniodysplasia, mesodermal in dog

• Retinal pigment epithelial dystrophy in dog

• Cerebellar cortical atrophy in dog

• Vasculopathy in dog

• Dermatosis in dog

• Osteochondromatosis in dog

• Hypertrichosis in dog

• Coloboma in dog

• Spina bifida in dog

• Alexander disease in dog

• Neuropathy, giant axonal in dog

• Tachycardia in dog

• Epidermolysis bullosa, dystrophic in dog

• Laryngeal paralysis in dog

• Budd-chiari syndrome in dog

• Spinal dysraphism in dog

• Myclin defect in dog

• Myotonia in dog

• Ataxia, progressive in dog

• Platelet delta-storage pool disease in dog

• Horner syndrome in dog

• Hypergammaglobulinaemia in dog

• Dermatofibrosis in dog

• Ectromelia in dog

• Hemivertebrae in dog

• Onychodystrophy in dog

• Retinoschisis in dog

• Alloimmune haemolytic anaemia of the newborn in dog

• Amyloidosis, AA in dog

• Bullous pemphigoid antigen in dog

• Retinal and skeletal dysplasia in dog

• Atrial fibrillation in dog

• Polyglandular autoimmune syndrome, type II in dog

• Stomatocytosis in dog

• Polyuria in dog

• Genu valgum in dog

• Hyperlipidaemia in dog

• Reduced glutathione deficiency, unclassified in dog

• Osteodystrophy in dog

• Ascites in dog

• Myopathy in dog

• Fragmented coronoid process in dog

• Sex reversal: XX male in dog

• Neuronal abiotrophy in dog

• Myelopathy in dog

• Rhabdomyolysis in dog

• Pulmonary stenosis in dog

• Neuropathy, peripheral in dog

• Cleft lip in dog

• Renal dysplasia in dog

• Blood group system C in dog

• Respiratory distress syndrome in dog

• Masticatory muscle myositis in dog

• Spondylosis deformans in dog

• Chondrodystrophy in dog

• Acetabular dystrophy in dog

• Wilson disease in dog

• Von Willebrand disease III in dog

• Von Willebrand disease I in dog

• Von Willebrand disease in dog

• Vitiligo in dog

• Ventricular septal defect in dog

• Ventricular arrhythmias and sudden death in dog

• Various disorders in dog

• Valvular pulmonic stenosis in dog

• Urolith, cystine in dog

• Urolithiasis in dog

• Uric acid excretion in dog

• Tremor syndrome with central axonopathy in dog

• Tremor in dog

• Transitional vertebral segments in dog

• Thyroiditis in dog

• Thromboxane responsiveness of platelets in dog

• Thrombopathia in dog

• Thrombocytopathy in dog

• Thrombocytopaenia in dog

• Thrombasthenia in dog

• Tetralogy of fallot in dog

• Testicular feminization in dog

• Tapetal degeneration in dog

• Tail chasing in dog

• Systemic lupus erythematosus in dog

• Swimming pup syndrome in dog

• Sudden death in dog

• Subaortic stenosis in dog

• Spinal muscular atrophy in dog

• Sodium-potassium-ATPase, high activity in dog

• Shoulder luxation in dog

• Short spine in dog

• Tremor, X-linked in dog

• Sex reversal in dog

• Severe combined immunodeficiency disease, X-linked in dog

• PRA-rod-cone dystrophy type 1 in dog

• Rod-cone dysplasia in dog

• Right ventricular cardiomyopathy in dog

• Review in dog

• Retinal degeneration II in dog

• Renal nephropathy in dog

• Renal insufficiency in dog

• Quadriplegia and amblyopia in dog

• Pyruvate kinase deficiency of erythrocyte in dog

• Pseudoachondroplastic dysplasia in dog

• Progressive retinal atrophy, X-linked in dog

• Progressive retinal atrophy in dog

• Progressive axonopathy in dog

• Prognathism in dog

• Prekallikrein deficiency in dog

• Portosystemic shunt in dog

• Portal vein hypoplasia, congenital in dog

• Polyneuropathy, distal sensorimotor in dog

• Polydactyly in dog

• Polycystic monophrosis in dog

• Polyarthritis in dog

• Pneumothorax in dog

• Platelet function defect in dog

• Persistent right aortic arch in dog

• Persistent Mullerian duct syndrome in dog

• Persistence of immature pyruvate kinase and hexokinase isozymes in dog

• Pelger-Huet anomaly in dog

• Patent ductus arteriosus and pulmonary hypertension in dog

• Patent ductus arteriosus in dog

• Patellar luxation in dog

• Pancreatic insufficiency, exocrine in dog

• Osteogenesis imperfecta in dog

• Osteochondrosis dissecans in dog

• Osteochondrosis in dog

• Osteochondroma causing progressive posterior paresis in dog

• Osteochondritis dissecans in dog

• Osteoarthritis in dog

• Osmotic resistance of erythrocytes in dog

• Orchitis in dog

• Optic nerve hypoplasia, bilateral in dog

• Optic chiasm, absence of in dog

• Oesophageal motility disorder in dog

• Oedema, lethal congenital in dog

• Ocular disease in dog

• Ocular defects in dog

• Occipital dysplasia in dog

• Nystagmus, congenital in dog

• Hemeralopia in dog

• Niemann-Pick disease in dog

• Neurogenic muscular atrophy in dog

• Neuroaxonal dystrophy in dog

• Nervous in dog

• Nephrotic syndrome in dog

• Nephropathy in dog

• Nephritis in dog

• Necrotising myelopathy in dog

• Narcolepsy in dog

• Myopathy, progressive, subacute in dog

• Myopathy, mitochondrial in dog

• Myopathy, congenital in dog

• Myopathia, sex-linked in dog

• Myoclonus epilepsy of Lafora in dog

• Myasthenic syndrome, congenital in dog

• Myasthenia gravis in dog

• Muscular dystrophy, dysphagia-associated in dog

• Muscular dystrophy, Duchenne and Becker types in dog

• Muscular dystrophy in dog

• Muscular atrophy, spinal in dog

• Mucopolysaccharidosis VII in dog

• Mucopolysaccharidosis VI in dog

• Mucopolysaccharidosis in dog

• Mitral valve disease in dog

• Mitral stenosis in dog

• Mislocated polydontic maxillary incisor teeth in dog

• Microphthalmia in dog

• Metabolic disorder in dog

• Megaoesophagus in dog

• Megakaryoblastic leukaemia in dog

• Malignant hyperthermia in dog

• Histiocytosis, malignant in dog

• Lymphoedema in dog

• Leukocyte adhesion deficiency in dog

• Lens luxation in dog

• Legg-Calve-Perthes disease in dog

• Krabbe disease in dog

• Kartagener syndrome in dog

• Hypothalamic dysplasia in dog

• Hepatic encephalopathy in dog

• Dysautonomia in dog

• Calcification of intervertebral discs in dog

• Fragile site in dog

• Iris defects in dog

• Iris atrophy in dog

• Intestinal cobalamin malabsorption in dog

• Inborn error of hepatic metabolism in dog

• Immunoglobulin A glomerulonephropathy in dog

• Immunoglobulin A deficiency in dog

• Immunodeficiency in dog

• Hypotrichosis in dog

• Hypothyroidism in dog

• Hypoprothrombinaemia in dog

• Hypolipoproteinaemia in dog

• Hypogonadism in dog

• Hypoadrenocorticism, primary in dog

• Hypoadrenocorticism in dog

• Neuropathy, hypertrophic in dog

• Heart disease, hypertrophic in dog

• Cardiomyopathy, hypertrophic in dog

• Hypertension, essential in dog

• Hypertension in dog

• Hyperparathyroidism in dog

• Hyperlipoproteinaemia in dog

• Hyperkinesis in dog

• Hypereosinophilic syndrome in dog

• Hyperbilirubinaemia, unclassified in dog

• Hyperadrenocorticism in dog

• Hydrocephalus in dog

• Hodgkin disease in dog

• Hip dysplasia in dog

• High acid excretion in dog

• Hernia, umbilical in dog

• Hernia, oesophageal hiatal in dog

• Hernia, inguinal in dog

• Hernia, hiatal in dog

• Hernia, diaphragmatic in dog

• Hernia in dog

• Hepatic fibrosis, idiopathic in dog

• Hepatic encephalopathy, portosystemic in dog

• Heart defect, congenital in dog

• Haemolytic uremic syndrome in dog

• Haemolytic anaemia, primary autoimmune in dog

• Haemolytic anaemia, nonspherocytic in dog

• Haemolytic anaemia, autoimmune in dog

• Haemolytic anaemia in dog

• Granule cell type cerebellar hypoplasia in dog

• Glycogen storage disease VII in dog

• Glycogen storage disease II in dog

• Glycogen storage disease I in dog

• Glycogen storage disease in dog

• Glossopharyngeal defect in dog

• Glomerulonephropathy in dog

• Glomerulonephritis in dog

• Glaucoma in dog

• Gingival hypertrophy in dog

• Gaucher disease, type I in dog

• Gastric dilatation volvulus syndrome in dog

• Gangliosidosis, GM2 in dog

• Gangliosidosis, GM1 in dog

• Gangliosidosis in dog

• Galactosialidosis in dog

• Fucosidosis, alpha in dog

• Focal metatarsal fistula in dog

• Fanconi syndrome in dog

• Factor XII deficiency in dog

• Factor XI deficiency in dog

• Factor X deficiency in dog

• Factor VII deficiency in dog

• Eye defects in dog

• Exostosis, multiple in dog

• Epilepsy in dog

• Epidermolysis bullosa, junctionalis in dog

• Entropion in dog

• Endotoxin shock in dog

• Elbow subluxation in dog

• Elbow luxation in dog

• Elbow dysplasia in dog

• Elbow disease in dog

• Ectropion in dog

• Dwarfism, pituitary in dog

• Dwarfism with retinal dysplasia in dog

• Dwarfism with anaemia in dog

• Dwarfism in dog

• Diabetes mellitus in dog

• Diabetes insipidus in dog

• Diabetes in dog

• Dermoid sinus in dog

• Dermatomyositis in dog

• Dermatitis, atopic in dog

• Degenerative myopathy of obturator-externus in dog

• Degenerative myelopathy in dog

• Deafness in dog

• Cystinuria in dog

• Cystic bone lesions in dog

• Neutropenia, cyclic in dog

• Cushing disease in dog

• Cryptorchidism in dog

• Cranioschisis in dog

• Craniomandibular osteopathy in dog

• Coxofemoral luxation in dog

• Coxofemoral dysplasia in dog

• Corneal dystrophy in dog

• Corneal dermoid in dog

• Cor triatriatum Dexter in dog

• Conotruncal heart malformations in dog

• Collie eye anomaly in dog

• Coat length in dog

• Coat colour, merle in dog

• Coat colour, albinism in dog

• Coat colour in dog

a href="http://www.ncbi.nlm.nih.gov/omia/389 Cleft palate in dog]

• Cleft alveolus and lip in dog

• Chondrodysplasia in dog

• Neuronal Ceroid Lipofuscinosis, Ceroid Lipofuscinosis in dog

• Cerebellar hypoplasia in dog

• Cerebellar abiotrophy in dog

• Cerebellar Purkinje cell degeneration in dog

• Central core myopathy in dog

• Cauda equina syndrome in dog

• Cataract in dog

• Carpal subluxation in dog

• Cardiovascular malformations in dog

• Cardiomyopathy, dilated in dog

• Cardiomyopathy in dog

• Calcinosis circumscripta in dog

• Calcification of intervertebral discs in dog

• Tail, short in dog

• Brachydactyly in dog

• Brachycephalic airway obstruction syndrome in dog

• Blood group system Tr in dog

• Blood group system D in dog

• Blood group system in dog

• Bleeding disorder in dog

• Black hair follicle dysplasia in dog

• Autoimmune thrombocytopenia in dog

• Atrial septal defect in dog

• Ataxia, cerebellar in dog

• Ataxia in dog

• Arthritis, rheumatoid in dog

• Aphakia in dog

• Aortic stenosis, subvalvular in dog

• Taillessness in dog

• Ankylosing spondylitis in dog

• Anaemia, congenital hypoplastic, of Blackfan and Diamond in dog

• Amyloidosis, renal in dog

• Amyloidosis in dog

• Alzheimer disease in dog

• Alpha-1-antitrypsin deficiency in dog

• Alopecia, colour mutant in dog

• Alopecia in dog

• Alloxan-diabetes in dog

• Afibrinogenaemia in dog

• Adrenal cortical atrophy in dog

• Acute posterior paresis in dog

• Achondroplasia in dog

• Haemophilia A in dog

• Haemophilia B in dog

• Nephritis, autosomal dominant in dog

• Nephritis, X-linked in dog

• Goitre, familial in dog

• Ehlers-Danlos syndrome in dog

• C3 deficiency in dog

• Otitis externa, susceptibility to in dog

• Mycosis fungoides in dog

• Mucopolysaccharidosis I in dog

• Thrombocytopenic purpura, autoimmune in dog

• Hernia, perineal in dog

• Polymicrogyria and asymmetrical ventricular dilation in dog

• Hepatitis, neonatal in dog

• Hepatitis, chronic active in dog

External Links

External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.

• Online Mendelian Inheritance in Animals | Search for Canis familiaris
• University of Georgia College of Veterinary Medicine The Canine Estrous Cycle
• Comparative Placentation Dog

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Cite this page: Hill, M.A. (2024, April 27) Embryology Dog Development - Abnormalities. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Dog_Development_-_Abnormalities

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© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G