ANAT2341 Lab 5: Difference between revisions

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{{ANAT2341Lab5}}
{{ANAT2341Lab5}}
==Introduction==
==1. QUIZ==


This laboratory class will take you through the development of the gastrointestinal tract and respiratory system. Take your time working through the online materials and understand the sequence and timing of developmental events.
==2. Guest Lecturer: Dr. Vashe Chandrakanthan (UNSW) - Cardiac and Vascular Development and Haematopoiesis==
[[File:Vashe_Chandrakanthan_profile_photo.jpg]]


'''Adult Gastrointestinal and Respiratory Tracts'''
Dr Vashe Chandrakanthan earned his PhD in Medicine from University of Sydney and completed his postdoctoral studies at the Victor Chang Cardiac Research Institute in Sydney. Currently he is a Research Fellow at the Lowy Cancer Research Centre at the UNSW Australia. He is a member of the adult cancer program where he heads the mesenchymal stem cell biology team. He joined the stem cell program to help setting up a regenerative medicine program at the UNSW Australia. Dr Chandrakanthan’s primary research interest lies in the field of developmental and molecular biology of stem cells. During his tenure at the Lowy Cancer Research Centre, in addition to setting up the regenerative medicine program, he has lineage traced mesenchymal stem cells and evaluated their contribution to various tissues in the mouse embryo with a particular focus on their role in haematopoiesis.


{|
'''References:'''
| [[File:Adult gastrointestinal tract cartoon02.jpg|300px]]
Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A, 2016, 'PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113 (link is external)
| valign=bottom|[[File:Adult gastrointestinal tract cartoon01.jpg|300px]]
| [[File:Bronchi_lungs.jpg|300px]]
|}


==Textbooks==
Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113 (link is external)


===The Developing Human: Clinically Oriented Embryology===
Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15 (link is external)
{|
|-
| {{MPT2011cover_citation}}
|
* [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4377-2002-0..00011-4&isbn=978-1-4377-2002-0&uniqId=330028653-2#4-u1.0-B978-1-4377-2002-0..00011-4 Chapter 11 – Alimentary System]
* [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4377-2002-0..00008-4&isbn=978-1-4377-2002-0&uniqId=330028653-2#4-u1.0-B978-1-4377-2002-0..00008-4 Chapter 8 – Body Cavities and Diaphragm]
* [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.mdconsult.com/books/page.do?eid=4-u1.0-B978-1-4377-2002-0..00010-2&isbn=978-1-4377-2002-0&uniqId=330028653-2#4-u1.0-B978-1-4377-2002-0..00010-2 Chapter 10 – Respiratory System]
|}
 
===Larsen's Human Embryology===
{| border='0px'
|-
| {{SBBF2009cover_citation}}
|
* [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-0-443-06811-9&eid=4-u1.0-B978-0-443-06811-9..10014-4 Chapter 14 - Development of the Gastrointestinal Tract]
* [http://er.library.unsw.edu.au/er/cgi-bin/eraccess.cgi?url=http://www.mdconsult.com/books/linkTo?type=bookPage&isbn=978-0-443-06811-9&eid=4-u1.0-B978-0-443-06811-9..10011-9 Chapter 11 - Development of the Respiratory System and Body Cavities]
|}
 
===UNSW Embryology===
{|
| {{Embryo logocitation}}
| {{Gastrointestinal Tract Links}}
 
{{Respiratory Links}} | [[Anatomy_of_the_Human_Body_by_Henry_Gray#947_Respiratory|Gray's 1918 Anatomy - The Respiratory Apparatus]]
 
External Link:  [http://8e.devbio.com/article.php?ch=15&id=157 '''Developmental Biology''' 8e Online - Lung Branching Morphogenesis]
|}


Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, vol. 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55 (link is external)


Marks-Bluth J; Khanna A; Chandrakanthan V; Thoms J; Bee T; Eich C; Kang YC; Knezevic K; Qiao Q; Fitch S, 2015, 'SMAD1 and SMAD5 expression is coordinately regulated by FLI1 and GATA2 during endothelial development', Molecular and Cellular Biology, vol. 35, pp. 2165 - 2172, http://dx.doi.org/10.1128/MCB.00239-15 (link is external)
{{ANAT2341Lab5Footer}}
{{ANAT2341Lab5Footer}}

Revision as of 11:53, 13 December 2016

Lab 5: Introduction | Trilaminar Embryo | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | Online Assessment

1. QUIZ

2. Guest Lecturer: Dr. Vashe Chandrakanthan (UNSW) - Cardiac and Vascular Development and Haematopoiesis

Vashe Chandrakanthan profile photo.jpg

Dr Vashe Chandrakanthan earned his PhD in Medicine from University of Sydney and completed his postdoctoral studies at the Victor Chang Cardiac Research Institute in Sydney. Currently he is a Research Fellow at the Lowy Cancer Research Centre at the UNSW Australia. He is a member of the adult cancer program where he heads the mesenchymal stem cell biology team. He joined the stem cell program to help setting up a regenerative medicine program at the UNSW Australia. Dr Chandrakanthan’s primary research interest lies in the field of developmental and molecular biology of stem cells. During his tenure at the Lowy Cancer Research Centre, in addition to setting up the regenerative medicine program, he has lineage traced mesenchymal stem cells and evaluated their contribution to various tissues in the mouse embryo with a particular focus on their role in haematopoiesis.

References: Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A, 2016, 'PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113 (link is external)

Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113 (link is external)

Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15 (link is external)

Huang Y; Thoms JAI; Tursky ML; Knezevic K; Beck D; Chandrakanthan V; Suryani S; Olivier J; Boulton A; Glaros EN, 2016, 'MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation', Leukemia, vol. 30, pp. 1552 - 1561, http://dx.doi.org/10.1038/leu.2016.55 (link is external)

Marks-Bluth J; Khanna A; Chandrakanthan V; Thoms J; Bee T; Eich C; Kang YC; Knezevic K; Qiao Q; Fitch S, 2015, 'SMAD1 and SMAD5 expression is coordinately regulated by FLI1 and GATA2 during endothelial development', Molecular and Cellular Biology, vol. 35, pp. 2165 - 2172, http://dx.doi.org/10.1128/MCB.00239-15 (link is external)

Lab 5: Introduction | Trilaminar Embryo | Early Embryo | Late Embryo | Fetal | Postnatal | Abnormalities | Online Assessment


ANAT2341 Course Timetable  
Week (Mon) Lecture 1 (Mon 1-2pm) Lecture 2 (Tue 3-4pm) Practical (Fri 1-3pm)
Week 2 (1 Aug) Introduction Fertilization Lab 1
Week 3 (8 Aug) Week 1 and 2 Week 3 Lab 2
Week 4 (15 Aug) Mesoderm Ectoderm Lab 3
Week 5 (22 Aug) Early Vascular Placenta Lab 4
Week 6 (29 Aug) Gastrointestinal Respiratory Lab 5
Week 7 (5 Sep) Head Neural Crest Lab 6
Week 8 (12 Sep) Musculoskeletal Limb Development Lab 7
Week 9 (19 Sep) Renal Genital Lab 8
Mid-semester break
Week 10 (3 Oct) Public Holiday Stem Cells Lab 9
Week 11 (10 Oct) Integumentary Endocrine Lab 10
Week 12 (17 Oct) Heart Sensory Lab 11
Week 13 (24 Oct) Fetal Birth and Revision Lab 12

ANAT2341 2016: Moodle page | ECHO360 | Textbooks | Students 2016 | Projects 2016

ANAT2341Lectures - Textbook chapters  
Lecture (Timetable) Textbook - The Developing Human Textbook - Larsen's Human Embryology
Embryology Introduction Introduction to the Developing Human
Fertilization First Week of Human Development Gametogenesis, Fertilization, and First Week
Week 1 and 2 Second Week of Human Development Second Week: Becoming Bilaminar and Fully Implanting
Week 3 Third Week of Human Development Third Week: Becoming Trilaminar and Establishing Body Axes
Mesoderm Fourth to Eighth Weeks of Human Development Fourth Week: Forming the Embryo
Ectoderm Nervous System Development of the Central Nervous System
Early Vascular Cardiovascular System Development of the Vasculature
Placenta Placenta and Fetal Membranes Development of the Vasculature
Endoderm - GIT Alimentary System Development of the Gastrointestinal Tract
Respiratory Respiratory System Development of the Respiratory System and Body Cavities
Head Pharyngeal Apparatus, Face, and Neck Development of the Pharyngeal Apparatus and Face
Neural Crest Nervous System Development of the Peripheral Nervous System
Musculoskeletal Muscular System Development of the Musculoskeletal System
Limb Development of Limbs Development of the Limbs
Renal Urogenital System Development of the Urinary System
Genital Urogenital System Development of the Urinary System
Stem Cells
Integumentary Integumentary System Development of the Skin and Its Derivatives
Endocrine Covered through various chapters (see also alternate text), read head and neck, neural crest and renal chapters.
Endocrinology Textbook - Chapter Titles  
Nussey S. and Whitehead S. Endocrinology: An Integrated Approach (2001) Oxford: BIOS Scientific Publishers; ISBN-10: 1-85996-252-1.

Full Table of Contents

Heart Cardiovascular System Development of the Heart
Sensory Development of Eyes and Ears Development of the Eyes
Fetal Fetal Period Fetal Development and the Fetus as Patient
Birth and Revision
Additional Textbook Content - The following concepts also form part of the theory material covered throughout the course.
  1. Principles and Mechanisms of Morphogenesis and Dysmorphogenesis
  2. Common Signaling Pathways Used During Development
  3. Human Birth Defect

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link

Cite this page: Hill, M.A. (2024, April 26) Embryology ANAT2341 Lab 5. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/ANAT2341_Lab_5

What Links Here?
© Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G
Retrieved from ‘https://embryology.med.unsw.edu.au/embryology/index.php?title=ANAT2341_Lab_5&oldid=260949’
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