Lecture - Integumentary Development: Difference between revisions
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{{ | ==Introduction== | ||
[[File:Hair histology.jpg|thumb|300px|'''Adult skin histology''' showing epidermis, dermis and hypodermis as well as specializations, such as hair follicles and sweat glands]] | |||
The skin provides a barrier between ourselves and our environment (temperature, water, UV), and contains specializations in different regions including hair, nails, teeth, glands and sensory receptors. In other species there are also specializations of beaks, scales and feathers. | |||
The two major tissue organizations of epithelial (ectoderm, epidermis) and mesenchyme (mesoderm connective tissue, dermis and hypodermis) are shown within skin. In addition, we have also have extensive populating by melanocytes (neural crest) and sensory nerve endings. | |||
Possibly the first epithelial tissue specialization from which arose other epithelial specializations now located inside the body. The external skin associated structures have many different roles and functions. This system is also an excellent model for distribution or "pattern" and adult stem cells. | |||
[[Media:ANAT2341_2017_Lecture_16_-_Integumentary_System_.pdf|'''Integumentary Lecture PDF''']] | |||
<center></center> | |||
Shown below on this page is for only background information for this topic. | |||
==Textbooks== | |||
{| class="wikitable mw-collapsible mw-collapsed" | |||
! colspan=2|References | |||
|- | |||
| width=100px|{{Embryo logocitation}} | |||
| {{Integumentary Links}} | |||
[[Media:2015ANAT2341_Lecture_14_-_Beverdam-Integumentary Development.pdf|2015 Integumentary Lecture Slides PDF]] | [[Media:ANAT2341_Lecture_4_-_Beverdam_-_Integumentary_System.pdf|2014 PDF]] | [[2010_Lecture_22|2010 Lecture]] | |||
|- | |||
| [[File:The Developing Human, 10th edn.jpg|90px]] | |||
| {{MPT2015APAcitation}} (links available to UNSW students) | |||
* [http://ebookcentral.proquest.com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074364&ppg=578 Integumentary System] | |||
|- | |||
| [[File:Larsen's human embryology 5th ed.jpg|90px]] | |||
| {{SBBF2015APAcitation}} | |||
The following chapter links only work with a UNSW Library connection. | |||
* [http://ebookcentral.proquest.com.wwwproxy1.library.unsw.edu.au/lib/unsw/reader.action?docID=2074524&ppg=173 Development of the Skin and Its Derivatives] | |||
|- | |||
| '''Links:''' [[Embryology Textbooks]] | |||
|} | |||
== Objectives == | |||
{| | |||
| | |||
* Understand the embryonic origin and differentiation of the epidermis and dermis. | |||
* Understand the formation of hair and nails. | |||
* Understand the formation of sweat glands, mammary glands. | |||
* Understand the formation of teeth. | |||
* Brief understanding of associated abnormalities. | |||
| [[File:Skin structure cartoon.jpg|300px]] | |||
Skin structure cartoon | |||
|} | |||
===Online Textbooks=== | |||
* '''Developmental Biology''' 6th ed. Gilbert, Scott F. Sunderland (MA): Sinauer Associates, Inc.; c2000. [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=dbio.figgrp.2934 Development of the hair follicles in fetal human skin] | [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=dbio.figgrp.3140 Image - Coordinated differentiation and morphogenesis in the mammalian tooth] | [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=dbio.box.3139 Tooth Development] | |||
* '''Eurekah Bioscience Collection''' [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=eurekah.figgrp.42334 Role of GLI proteins in embryonic hair follicle development] | |||
* '''Molecular Biology of the Cell''' [http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=mboc4.figgrp.1651 FGF5 is a negative regulator of hair formation] | |||
* '''Blue Histology''' [http://www.lab.anhb.uwa.edu.au/mb140/CorePages/Integumentary/Integum.htm Integumentary System] | |||
==External Links== | |||
{{External Links}} | |||
* Teeth - [http://bite-it.helsinki.fi/ University of Helsinki - Gene Expression in Tooth] | [http://www.ada.org/public/topics/tooth.asp American Dental Association Overview - Tooth] | [http://www.simplestepsdental.com/SS/ihtSS/r.WSIHW000/st.31843/t.31886/pr.3.html Columbia University Medical Centre - Illustrations: How a Tooth Decays] | [http://www.merck.com/mmhe/sec08/ch114/ch114a.html Merck - Tooth disorders] | [http://kidshealth.org/parent/pregnancy_newborn/common/teething.html Nemours Foundation - Teething Tots] | |||
* Neonatal Dermatology - [http://www.adhb.govt.nz/newborn/TeachingResources/Dermatology/Dermatology.htm NZ National Women's Health] | |||
* Dermatology Image Atlas - [http://dermatlas.med.jhmi.edu/derm/ DermAtlas] | |||
{{#pmid:18459147}} | |||
[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2561923&rendertype=figure&id=F1 Figure 1 Key steps in the development of three major ectodermal appendages] | |||
==Terms== | |||
{{Integumentary terms}} | |||
[[Category:Science-Undergraduate]] | |||
[[Category:Integumentary]] [[Category:Hair]] | |||
{{2017ANAT2341 footer}} |
Latest revision as of 14:06, 10 November 2019
Introduction
The skin provides a barrier between ourselves and our environment (temperature, water, UV), and contains specializations in different regions including hair, nails, teeth, glands and sensory receptors. In other species there are also specializations of beaks, scales and feathers.
The two major tissue organizations of epithelial (ectoderm, epidermis) and mesenchyme (mesoderm connective tissue, dermis and hypodermis) are shown within skin. In addition, we have also have extensive populating by melanocytes (neural crest) and sensory nerve endings.
Possibly the first epithelial tissue specialization from which arose other epithelial specializations now located inside the body. The external skin associated structures have many different roles and functions. This system is also an excellent model for distribution or "pattern" and adult stem cells.
Shown below on this page is for only background information for this topic.
Textbooks
Objectives
|
Skin structure cartoon |
Online Textbooks
- Developmental Biology 6th ed. Gilbert, Scott F. Sunderland (MA): Sinauer Associates, Inc.; c2000. Development of the hair follicles in fetal human skin | Image - Coordinated differentiation and morphogenesis in the mammalian tooth | Tooth Development
- Eurekah Bioscience Collection Role of GLI proteins in embryonic hair follicle development
- Molecular Biology of the Cell FGF5 is a negative regulator of hair formation
- Blue Histology Integumentary System
External Links
External Links Notice - The dynamic nature of the internet may mean that some of these listed links may no longer function. If the link no longer works search the web with the link text or name. Links to any external commercial sites are provided for information purposes only and should never be considered an endorsement. UNSW Embryology is provided as an educational resource with no clinical information or commercial affiliation.
- Teeth - University of Helsinki - Gene Expression in Tooth | American Dental Association Overview - Tooth | Columbia University Medical Centre - Illustrations: How a Tooth Decays | Merck - Tooth disorders | Nemours Foundation - Teething Tots
- Neonatal Dermatology - NZ National Women's Health
- Dermatology Image Atlas - DermAtlas
Duverger O & Morasso MI. (2008). Role of homeobox genes in the patterning, specification, and differentiation of ectodermal appendages in mammals. J. Cell. Physiol. , 216, 337-46. PMID: 18459147 DOI.
Figure 1 Key steps in the development of three major ectodermal appendages
Terms
Integumentary Terms | ||
---|---|---|
Integumentary Development
| ||
|
2017 ANAT2341 - Timetable | Course Outline | Group Projects | Moodle | Tutorial 1 | Tutorial 2 | Tutorial 3 |
Labs: 1 Fertility and IVF | 2 ES Cells to Genome Editing | 3 Preimplantation and Early Implantation | 4 Reproductive Technology Revolution | 5 Cardiac and Vascular Development | 6 CRISPR-Cas9 | 7 Somitogenesis and Vertebral Malformation | 8 Organogenesis | 9 Genetic Disorders | 10 Melanocytes | 11 Stem Cells | 12 Group |
Lectures: 1 Introduction | 2 Fertilization | 3 Week 1/2 | 4 Week 3 | 5 Ectoderm | 6 Placenta | 7 Mesoderm | 8 Endoderm | 9 Research Technology | 10 Cardiovascular | 11 Respiratory | 12 Neural crest | 13 Head | 14 Musculoskeletal | 15 Limb | 16 Renal | 17 Genital | 18 Endocrine | 19 Sensory | 20 Fetal | 21 Integumentary | 22 Birth | 23 Stem cells | 24 Revision |
Student Projects: 1 Cortex | 2 Kidney | 3 Heart | 4 Eye | 5 Lung | 6 Cerebellum |