Lecture - Stem Cells: Difference between revisions
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* Future of regenerative medicine | * Future of regenerative medicine | ||
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|'''The Nobel Prize in Physiology or Medicine 2012''' | |||
| Awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "''for the discovery that mature cells can be reprogrammed to become pluripotent''" | |||
* '''Yamanaka Factors''' Are a set of 4 transcription factors when introduced into cells induces stem cell formation. PMID 16904174 | PMID 18035408 | PMID 20535199 | |||
* '''John Gurdon''' used nuclear transplantation and cloning to show that the nucleus of a differentiated somatic cell retains the totipotency necessary to form a whole organism. | |||
**[http://www.sciencedirect.com/science/article/pii/S0960982203006845 2003 Current Biology Interview] PMID 14521852 2009 Interview - [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615171 "The birth of cloning"] PMID 19132124 | |||
[[Stem Cells - Induced]] | |||
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| NIH Report | | NIH Report |
Revision as of 12:20, 27 October 2014
Introduction
Embryology is all about stem cells, a single cell (zygote) divides and differentiates to form all the tissues throughout the body. Furthermore within some tissues, stem cells remain to continuously replace cells that are lost through the life of that tissue. In recent years Scientific and general interest in this topic has increased due to the many issues that surround this specialised cell type. This lecture will introduce the various types/sources of stem cells as well as their practical and therapeutic potentials. A brief discussion of the pros and cons of different types of stem cells currently investigated in the field of medical research will be discussed.
Here are the slides for today's lecture Media:ANAT2341Beverdam2014 - Stem cell biology and technology.pdf
Objectives
- Tissue development and regeneration Stem cell biology
- Stem cell niches
- Stem cell regulation
- Stem cells and cancer Regenerative medicine
- Stem cell sources
- Future of regenerative medicine
Lecture Resources
References | |
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Hill, M.A. (2020). UNSW Embryology (20th ed.) Retrieved May 8, 2024, from https://embryology.med.unsw.edu.au | |
The Nobel Prize in Physiology or Medicine 2012 | Awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"
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NIH Report | NIH - Regenerative Medicine 2006 |
References
- 2014 Course: Week 2 Lecture 1 Lecture 2 Lab 1 | Week 3 Lecture 3 Lecture 4 Lab 2 | Week 4 Lecture 5 Lecture 6 Lab 3 | Week 5 Lecture 7 Lecture 8 Lab 4 | Week 6 Lecture 9 Lecture 10 Lab 5 | Week 7 Lecture 11 Lecture 12 Lab 6 | Week 8 Lecture 13 Lecture 14 Lab 7 | Week 9 Lecture 15 Lecture 16 Lab 8 | Week 10 Lecture 17 Lecture 18 Lab 9 | Week 11 Lecture 19 Lecture 20 Lab 10 | Week 12 Lecture 21 Lecture 22 Lab 11 | Week 13 Lecture 23 Lecture 24 Lab 12
Student Projects - Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8 | Moodle