Gastrointestinal Tract - Intestine Development
Introduction
The part of the gastrointestinal tract (GIT) lying between the stomach and anus, is described as the intestines or bowel. This region is further divided anatomically and functionally into the small intestine or bowel (duodenum, jejunum and ileum) and large intestine or bowel (cecum and colon). Initially development concerns the midgut region, connected to the yolk sac, and the hindgut region, ending at the cloacal membrane. This is followed by two mechanical processes of elongation and rotation. Elongation, growth in length, leaves the midgut "herniated" at the umbilicus and external to the abdomen. Rotation, around a mesentery axis, establishes the anatomical position of the large intestine within the peritoneal space.
Embryonic Development
Week 4
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Week 8
Late embryonic small intestine commencing at the duodenum, continuing as ventrally herniated and returning to join the colon.
Molecular Factors
- Cdx (Caudal-type homeobox) group of ParaHox genes (mouse Cdx1, Cdx2 and Cdx4)[1]
Abnormalities
References
- ↑ <pubmed>20298182</pubmed>
Reviews
Articles
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Cite this page: Hill, M.A. (2024, May 3) Embryology Gastrointestinal Tract - Intestine Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Gastrointestinal_Tract_-_Intestine_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G