Gastrointestinal Tract - Gall Bladder Development: Difference between revisions
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* '''Embryology of the biliary tract'''<ref><pubmed>20551648</pubmed></ref> | * '''Embryology of the biliary tract'''<ref><pubmed>20551648</pubmed></ref> "A hepatic diverticulum appears in the ventral wall of the primitive midgut early in the 4th week of intrauterine life in the development of the human embryo. This small diverticulum is the anlage for the development of the liver, extrahepatic biliary ducts, gallbladder, and ventral pancreas. By the 5th week, all elements of the biliary tree are recognizable. Marked elongation of the common duct occurs with plugging of the lumen by epithelial cells. Recanalization of the lumen of the common duct starts at the end of the 5th week and moves slowly distally. By the 6th week, the common duct and ventral pancreatic bud rotate 180 degrees clockwise around the duodenum. Early in the 7th week, the bile and pancreatic ducts end in closed cavities of the duodenum. Between the early 8th and 12th week, hepatopancreatic ducts have both superior and inferior orifices." | ||
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==Embryonic Development== | ==Embryonic Development== | ||
Revision as of 16:12, 22 August 2011
Introduction
This section of notes gives an overview of Gall Bladder development, histology and abnormalities associated with the biliary system. In the adult, the gall bladder is a site of bile salt storage and concentration, to then be released into the small intestine where they act to solubilize dietary lipids by their detergent effect. Bile salts are a cholesterol derivative (breakdown product).
The transverse septum differentiates to form the hepatic diverticulum and the hepatic primordium, these two structures together will go on to form different components of the mature liver and gall bladder.
The hepatic diverticulum divides into two parts: pars hepatica (larger cranial part, primordium of the liver) and pars cystica (smaller ventral invagination, primordium of gall bladder).
The pars cystica vacuolates and expands, the stalk becoming the cystic duct. This structure is initially hollow, then solid (by proliferation of epithelial lining), and then recanalized occurs by vacuolation of this expanded epithelium. (some text above modified from Bani-Hani KE., 2005)
| Gall Bladder Histology | original page
Some Recent Findings
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Embryonic Development
Early embryonic gall bladder (Carnegie stage 13, Week 4)
Late embryonic gall bladder (Carnegie stage 22, Week 8)
Additional Images
See also Gall Bladder Histology
References
- ↑ <pubmed>20551648</pubmed>
Reviews
<pubmed>20551648</pubmed> <pubmed>20152372</pubmed> <pubmed>15853977</pubmed> <pubmed>15382016</pubmed>
Articles
<pubmed>21078254</pubmed> <pubmed>20191134</pubmed> <pubmed>16273658</pubmed>
Search Pubmed
July 2010
Search Bookshelf Gall Bladder Development
Search Pubmed Now: Gall Bladder Development
Glossary Links
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Cite this page: Hill, M.A. (2024, May 29) Embryology Gastrointestinal Tract - Gall Bladder Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Gastrointestinal_Tract_-_Gall_Bladder_Development
- © Dr Mark Hill 2024, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G