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| =Endocrine and Integumentary= | | ==1. Project Peer Assessment== |
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| {{Endocrine Links}}
| | No Quiz this week after mid-semester break. |
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| {{Integumentary Links}}
| | Complete the peer assessment exercise for your individual assessment this week. Write a brief balanced feedback for each project (other than your own). Paste this feedback on each group discussion page as well as your own student page, where I will provide feedback. |
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| ==Endocrine==
| | Below are the criteria used by the course coordinator for the final project assessment. |
| [[File:Stage 22 image 221.jpg|thumb|Developing Pituitary - Human Embryo Carnegie stage 22]]
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| * Begin by working through [[Endocrine_System_-_Carnegie_Stage_22|Endocrine Development by week 8]].
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| * Then look at the information on each endocrine organ on their related specific page.
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| {{Endocrine Links}} | | {{Group Assessment Criteria table}} |
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| ==Integumentary== | | ==2. Guest Lecturer - Dr Gonzalo Del Monte== |
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| {{Integumentary Links}}
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| ===Teeth===
| | [[Media:Lecture Heart Development UNSW 2-10-18 .pdf|'''Lecture Slides''']] |
| [[File:Fetal_head_lateral.jpg|thumb|Fetal Head (12 weeks) lateral]] | |
| [[File:Deciduous teeth.jpg|thumb|Deciduous teeth]]
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| [[File:Permanent teeth.jpg|thumb|Permanent teeth]]
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| * integumentary system specialization by '''epitheilal/mesenchymal''' interactions in development and develops with a major contribution from the neural crest.
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| ** ectoderm of the first pharyngeal arch and neural crest, ectomesenchymal cells.
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| * week 6 - odontogenesis begins, tooth bud
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| * 4 morphological stages describing the early tooth development: bud, cap, bell, and terminal differentiation
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| * 2 sets of teeth: 20 deciduous teeth, 32 permanent teeth
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| * differential rates of growth, shed at different times over 20 year period
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| * inductive influence of neural crest with overlying ectoderm
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| * tooth growth occurs in ossifying jaws
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| '''odontoblasts''' - neural crest-derived mesenchymal cells which differentiate under the influence of the enamel epithelium. Cells secrete predentin, calcifies to form dentin.
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| '''ameloblasts''' - inner enamel epithelium forms pre-ameloblasts differentiate and produce enamel
| | ===References=== |
| | Search PubMed: [https://www.ncbi.nlm.nih.gov/pubmed/?term=Del+Monte+G%5BAuthor%5D Del+Monte G] |
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| '''periodontal ligament''' - tooth is not anchored directly onto its bony socket (alveolar bone) but held in place by the periodontal ligament (PDL), a specialized connective tissue structure that surrounds the tooth root coating of cementum.
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| * ligament also act as; a shock absorber, transmitter of chewing forces (from tooth to bone), sensory information (heat, cold, pressure and pain).
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| ** collagen fiber bundles within the ligament are called "Sharpey's fibres".
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| '''Tooth Stages'''
| | {{#pmid:23178115}} |
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| Tooth development stages<ref name="PMID19266065"><pubmed>19266065</pubmed>| [http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2651620&tool=pmcentrez PMCID: PMC2651620]</ref>
| | {{#pmid:21311046}} |
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| {| | | {{#pmid:20890042}} |
| |-bgcolor="CEDFF2"
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| | width= 100px |'''Stage'''
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| | width= 210px |<center>'''Image'''</center>
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| | width= 100px |'''Human''' (weeks)
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| | lamina
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| | [[File:Tooth stage lamina.jpg|200px|lamina]]
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| | [[Week 6]]
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| |-bgcolor="F5FAFF"
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| | placode
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| | [[File:Tooth placode stage.jpg|200px|placode stage]]
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| | [[Week 7]]
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| | bud
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| | [[File:Tooth bud stage.jpg|200px|bud stage]]
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| | [[Week 8]]
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| |-bgcolor="F5FAFF"
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| |cap
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| | [[File:Tooth cap stage.jpg|200px|cap stage]]
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| | Week 11
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| | bell
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| | [[File:Tooth bell stage.jpg|200px|bell stage]]
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| | Week 14
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| |-bgcolor="F5FAFF"
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| |}
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| === Teeth Postnatal ===
| | {{#pmid:27044077}} |
| Deciduous teeth
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| * '''6 - 24 months''' - erupt from gums by pushing toward surface
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| * '''2 years''' - all deciduous teeth present
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| Permanent teeth
| | {{#pmid:27055868}} |
| * 6 years until early adult
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| * tooth bud lie in gums beneath deciduous teeth
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| * osteoclasts resorb deciduous teeth roots
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| * growth affects face shape
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| :'''Links:''' [[Integumentary_System_-_Tooth_Development|Tooth Development]]
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| ==Individual Assessment==
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| ==Group Project==
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| * Peer Assessment of your project should now appear on your group discussion page.
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| * Now you can make changes to your project based upon these reviews and your own concepts of how the project can be improved.
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| * At this time it is important that you interact with other group members to ensure they agree on the changes you may make.
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| * You may add additional content to your project.
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| * Look through the comments made by your peers and assemble a summary of good (positive) and bad (negative) feedback on your project.
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| ** What are the common features of peer comments?
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| * Fix those minor problems (formatting, image size, image labelling, text, referencing)
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| * Are there parts of your project where group members have not worked appropriately or contributed their work?
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| ** I will initially be discussing this with the groups individually. You will also have the opportunity to "feed back" contribution issues.
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| ===Plagiarism===
| | {{2018ANAT2341}} |
| Currently all students originally assigned to each group are listed as equal authors/contributors to their project. If you have not contributed the content you had originally agreed to, nor participated in the group work process, then you should contact the course coordinator immediately and either discuss your contribution or request removal from the group author list. Remember that all student online contributions are recorded by date, time and the actual contributed content. A similar email reminder will be sent to all current students.
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| Please note the [https://my.unsw.edu.au/student/atoz/Plagiarism.html Universities Policy regarding Plagiarism]
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| In particular this example:
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| :"Claiming credit for a proportion of work contributed to a group assessment item that is greater than that actually contributed;"
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| Academic Misconduct carries penalties. If a student is found guilty of academic misconduct, the penalties include warnings, remedial educative action, being failed in an assignment or excluded from the University for two years.
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| ----
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| ==SOMS Summer Research Awards==
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| * The Research Support Committee is pleased to announce that it will again be offering Summer Research Awards (SRAs).
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| * These awards are for undergraduate students carrying out supervised research in SOMS between November 2012 and February 2013.
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| * Successful students will receive $250 per week for 6 weeks of research. [http://medicalsciences.med.unsw.edu.au/SOMSWeb.nsf/page/Summer%20Research%20Awards More Information?]
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| ==References==
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| <references/>
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| {{2012ANAT2341}} | |
1. Project Peer Assessment
No Quiz this week after mid-semester break.
Complete the peer assessment exercise for your individual assessment this week. Write a brief balanced feedback for each project (other than your own). Paste this feedback on each group discussion page as well as your own student page, where I will provide feedback.
Below are the criteria used by the course coordinator for the final project assessment.
| Group Assessment Criteria
|
 Science Student Projects
- The key points relating to the topic that your group allocated are clearly described.
- The choice of content, headings and sub-headings, diagrams, tables, graphs show a good understanding of the topic area.
- Content is correctly cited and referenced.
- The wiki has an element of teaching at a peer level using the student's own innovative diagrams, tables or figures and/or using interesting examples or explanations.
- Evidence of significant research relating to basic and applied sciences that goes beyond the formal teaching activities.
- Relates the topic and content of the Wiki entry to learning aims of embryology.
- Clearly reflects on editing/feedback from group peers and articulates how the Wiki could be improved (or not) based on peer comments/feedback. Demonstrates an ability to review own work when criticised in an open edited wiki format. Reflects on what was learned from the process of editing a peer's wiki.
- Evaluates own performance and that of group peers to give a rounded summary of this wiki process in terms of group effort and achievement.
- The content of the wiki should demonstrate to the reader that your group has researched adequately on this topic and covered the key areas necessary to inform your peers in their learning.
- Develops and edits the wiki entries in accordance with the above guidelines.
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| More Information on Assessment Criteria | Science Student Projects
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2. Guest Lecturer - Dr Gonzalo Del Monte
Lecture Slides
References
Search PubMed: Del+Monte G
Del Monte G & Harvey RP. (2012). An endothelial contribution to coronary vessels. Cell , 151, 932-4. PMID: 23178115 DOI.
del Monte G, Casanova JC, Guadix JA, MacGrogan D, Burch JB, Pérez-Pomares JM & de la Pompa JL. (2011). Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis. Circ. Res. , 108, 824-36. PMID: 21311046 DOI.
Luna-Zurita L, Prados B, Grego-Bessa J, Luxán G, del Monte G, Benguría A, Adams RH, Pérez-Pomares JM & de la Pompa JL. (2010). Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation. J. Clin. Invest. , 120, 3493-507. PMID: 20890042 DOI.
Chandrakanthan V, Yeola A, Kwan JC, Oliver RA, Qiao Q, Kang YC, Zarzour P, Beck D, Boelen L, Unnikrishnan A, Villanueva JE, Nunez AC, Knezevic K, Palu C, Nasrallah R, Carnell M, Macmillan A, Whan R, Yu Y, Hardy P, Grey ST, Gladbach A, Delerue F, Ittner L, Mobbs R, Walkley CR, Purton LE, Ward RL, Wong JW, Hesson LB, Walsh W & Pimanda JE. (2016). PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells. Proc. Natl. Acad. Sci. U.S.A. , 113, E2306-15. PMID: 27044077 DOI.
Huang Y, Thoms JA, Tursky ML, Knezevic K, Beck D, Chandrakanthan V, Suryani S, Olivier J, Boulton A, Glaros EN, Thomas SR, Lock RB, MacKenzie KL, Bushweller JH, Wong JW & Pimanda JE. (2016). MAPK/ERK2 phosphorylates ERG at serine 283 in leukemic cells and promotes stem cell signatures and cell proliferation. Leukemia , 30, 1552-61. PMID: 27055868 DOI.
Science Student Projects
