2017 Group Project 1: Difference between revisions
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https://moodle.telt.unsw.edu.au/mod/hsuforum/view.php?id=1416354 | https://moodle.telt.unsw.edu.au/mod/hsuforum/view.php?id=1416354 | ||
==INFO teachers gave== | ==INFO teachers gave (temporary heading)== | ||
PubMed Searches: [http://www.ncbi.nlm.nih.gov/pubmed?term=Cerebral+Cortex+Development ''Cerebral Cortex Development''] | [http://www.ncbi.nlm.nih.gov/pubmed?term=Cerebrum+Development ''Cerebrum Development''] | PubMed Searches: [http://www.ncbi.nlm.nih.gov/pubmed?term=Cerebral+Cortex+Development ''Cerebral Cortex Development''] | [http://www.ncbi.nlm.nih.gov/pubmed?term=Cerebrum+Development ''Cerebrum Development''] |
Revision as of 20:43, 23 September 2017
2017 Student Projects | |||
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Cerebral Cortex
Mark Hill (talk) 15:59, 14 September 2017 (AEST) Feedback
- lots of sub-headings, but no actual text.
- no defined structure to the sequence of sub-headings.
- no research images related to what is an extensively researched topic.
- historic background of key research findings, put our understanding today in perspective.
- Lon list of abnormalities, with no description.
Introduction
( Susannah )
What is it?
For concept: https://www.youtube.com/watch?v=dNngOlsLuGI
You might find this helpful (although you need to request copyright permission):
"Difference Between Cerebrum and Cerebral Cortex." DifferenceBetween.Com. August 7, 2012. < http://www.differencebetween.com/difference-between-cerebrum-and-vs-cerebral-cortex/ >
Histology of Cerebral Cortex
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024757/ Z5177691 (talk) 22:37, 23 August 2017 (AEST)
Early Development of the Brain (and Nervous System)
( Eden )
For concept:
https://www.youtube.com/watch?v=XdN9i_ZWGho
https://embryology.med.unsw.edu.au/embryology/index.php/Neural_-_Cerebrum_Development
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989000/ https://embryology.med.unsw.edu.au/embryology/index.php/Neural_System_Development
Development of Cerebral Cortex
( Anna )
Terminology
- Corticogenesis:
- Zones:
- Ventricular zone
- Subventricular zone
- Cortical Plate
- Preplate: neural progenitor cells split into 2 regions
- Marginal zone:
- Subplate:
Timeline
Nature article: https://www.nature.com/nrn/journal/v9/n2/full/nrn2252.html
- E10.5-- VZ (ventricular zone) single layer of cells- have feet that attach to cerebral wall and start dividing. Slightly polarized.
- E11.5--cells begin to differentiate (PP/preplate) into “pioneer” neurons and move upward, laying molecular trail for subsequent differentiating neurons
- E13.5--VZ cells form secondary progenitor population in SVZ, PP (preplate pioneer) cells split into 2 zones (MZ and SP)
- MZ and SP cells tell newly differentiated and migrating cells where they are
- E14.5-17.5-- deep layers populated first and then superficial layers later
- The neuron senses the layer it is in and stops- condense in CP (cortical plate)
6 Layers
Layers I, II, III, IV, V, VI (see "Cortical Layer Review" Z5177691 (talk) 22:57, 23 August 2017 (AEST)
Cell Types
http://www.ruf.rice.edu/~lngbrain/Sidhya/
- Radial Glial cells--in developing cerebellum, hippocampus, cortex
- Migrating neurons glump onto radial glial to migrate- move up these RG cells
- RG Cells for migrating neurons that extend from VZ to get to the outer part of the cortex.
- Fibers that neurons use to migrate from VZ to their final destination
- Allows dividing cells (projector neurons)- to migrate not randomly but radially.
- Radial Glial Cells can divide as well→ overall process requires a lot of membrane
Cell Signaling
Anatomy of the Cerebral Cortex
( Jess)
You might find this helpful (although you need to request copyright permission): "Difference Between Cerebrum and Cerebral Cortex." DifferenceBetween.Com. August 7, 2012. < http://www.differencebetween.com/difference-between-cerebrum-and-vs-cerebral-cortex/ >
Functions of the Cerebral Cortex
( Jess)
For concept:
https://www.youtube.com/watch?v=n6zQbTT0yoY
Abnormalities
(Zainab)
(z5093005 )
Structural and Functional Abnormalities associated with Cerebral Cortex Development
DRAFT:
https://www.youtube.com/watch?v=luXDQrmMoUU
Abnormalities List- Draft:
PubMed Article: [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992410/ Another PubMed article to look at abnormalities
http://www.sciencedirect.com/science/article/pii/S0896627300807497
Corpus Callosum Agenesis
<html5media height="400" width="500">https://www.youtube.com/watch?v=7zOa3LLrHKc</html5media>
Fetal Alcohol Spectrum Disorder (FASD)
Fragile X-Syndrome
Focal cortical dysplasia (FCD)
Kallmann Syndrome
Lissencephaly
Classical (Type I) Lisssencephaly Cobblestone (Type II) lissencephaly
Hemimegalencephaly
Microcephaly
Microlissencephaly
Muscle-Eye-Brain Disease
Periventricular Heterotopia
Polymicrogyria
Rett Syndrome
Schizencephaly
Subcortical band heterotopia
Tuberous Sclerosis
Walker-Warburg
Group Discussion Area (temporary heading)
We are supposed to discuss the project here:
https://moodle.telt.unsw.edu.au/mod/hsuforum/view.php?id=1416354
INFO teachers gave (temporary heading)
PubMed Searches: Cerebral Cortex Development | Cerebrum Development
BMC Dev Biol Search: Cerebral Cortex Development
Recent papers
<pubmed limit=5>Cerebral+Cortex+Development</pubmed>
References
- ↑ ezzo - izzo, d. (2007, August 2). How the Body Works : The Corpus Callosum. Retrieved from https://www.youtube.com/watch?v=7zOa3LLrHKc