Sensory - Taste Development
|Embryology - 20 Feb 2018 Expand to Translate|
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These notes introduce the development of the sense of taste which can divided into five basic tastes: bitter, salty, sweet, umami (savoury) and sour. Current research appears to have displaced the historic concept of a tongue "map".
A study in rat suggests that neonatal changes in circumvallate papillae may result in postnatal changes in "taste".
In frogs, a large taste disc (TD) is the largest vertebrate gustatory organ. Postnatally, the sense of taste is also closely related to the sense of smell.
|Taste Links: Introduction | Student project | Tongue Development | Category:Taste|
|Senses Links: Introduction | Placodes | Hearing and Balance | Vision | Smell | Taste | Touch | Stage 22 | Category:Senses|
Some Recent Findings
|More recent papers|
This table shows an automated computer PubMed search using the listed sub-heading term.
References listed on the rest of the content page and the associated discussion page (listed under the publication year sub-headings) do include some editorial selection based upon both relevance and availability.
Jacob P Beckerman, Queen Alike, Erika Lovin, Martha Tamez, Josiemer Mattei The Development and Public Health Implications of Food Preferences in Children. Front Nutr: 2017, 4;66 PubMed 29326942
Francjan J van Spronsen, Margreet van Rijn, Uta Meyer, Anibh M Das Dietary Considerations in Tyrosinemia Type I. Adv. Exp. Med. Biol.: 2017, 959;197-204 PubMed 28755197
Jessica E Armstrong, David G Laing, Anthony L Jinks Taste-Elicited Activity in Facial Muscle Regions in 5-8-Week-Old Infants. Chem. Senses: 2017, 42(5);443-453 PubMed 28531312
Dengyong Liu, Shengjie Li, Nan Wang, Yajun Deng, Lei Sha, Shengmei Gai, Huan Liu, Xinglian Xu Evolution of Taste Compounds of Dezhou-Braised Chicken During Cooking Evaluated by Chemical Analysis and an Electronic Tongue System. J. Food Sci.: 2017; PubMed 28407240
Erin Sundseth Ross Flavor and Taste Development in the First Years of Life. Nestle Nutr Inst Workshop Ser: 2017, 87;49-58 PubMed 28315887
Week 6 - gustatory papilla, caudal midline near the foramen caecum
Week 6-7 - nerve fibers approach the lingual epithelium
Week 8 - nerves penetrate epitheilai basal lamina and synapse with undifferentiated, elongated, epithelial cells (taste bud progenitor cell)
Week 10 - shallow grooves above the taste bud primordium
Week 12 - first differentiated epithelial cells (Type II and III)
Week 12 -13 - maximum synapses between cells and afferent nerve fibers
Week 14 - 15 - taste pores develop, mucous
Week 18 - substance P detected in dermal papillae, not in taste bud primordia
3rd Trimester -
- Links: Timeline human development
Circumvallate papilla are tongue surface specialisation of large size, varying in number (8-12) forming an inverted letter V shape on the dorsum of the tongue immediately in front of the foramen cecum and sulcus terminals. Numerous "taste buds" are located on the sides of these circumvallate papilla (vallate papilla)as well as with fungiform papilla. The three types of tongue papillae from numerous to few are: filiform, fungiform and circumvallate.
Other adult locations include the fimbriæ linguæ, under surface of the soft palate, and on the posterior surface of the epiglottis.
Gustatory Cranial Sensory Neurons
Cranial nerves VII, IX and X have dual embryonic origins and provide both gustatory (taste) and non-gustatory (touch, pain, temperature) sensory innervation to the oral cavity of vertebrates.
- originate from epibranchial placodes
- innervate taste buds
- project centrally to the rostral nucleus of the solitary tract (NTS)
General Epithelial Innervation of the oral cavity
- originate from cranial neural crest
- innervation to the oropharynx
- project to non-gustatory hindbrain regions (spinal trigeminal nucleus)
(text based on: Embryonic origin of gustatory cranial sensory neurons.)
Section (B4) through head showing tongue and head structures.
Images and data.
- Jayaram Chandrashekar, Mark A Hoon, Nicholas J P Ryba, Charles S Zuker The receptors and cells for mammalian taste. Nature: 2006, 444(7117);288-94 PubMed 17108952
- Robin F Krimm Factors that regulate embryonic gustatory development. BMC Neurosci: 2007, 8 Suppl 3;S4 PubMed 17903280
- A Sbarbati, C Crescimanno, F Merigo, D Benati, P Bernardi, M Bertini, F Osculati A brief survey of the modifications in sensory-secretory organs of the neonatal rat tongue. Biol. Neonate: 2001, 80(1);1-6 PubMed 11474141
- Linda A Barlow, Ophir D Klein Developing and regenerating a sense of taste. Curr. Top. Dev. Biol.: 2015, 111;401-19 PubMed 25662267
- David Castillo, Kerstin Seidel, Ernesto Salcedo, Christina Ahn, Frederic J de Sauvage, Ophir D Klein, Linda A Barlow Induction of ectopic taste buds by SHH reveals the competency and plasticity of adult lingual epithelium. Development: 2014, 141(15);2993-3002 PubMed 24993944
- Akiyuki Taruno, Valérie Vingtdeux, Makoto Ohmoto, Zhongming Ma, Gennady Dvoryanchikov, Ang Li, Leslie Adrien, Haitian Zhao, Sze Leung, Maria Abernethy, Jeremy Koppel, Peter Davies, Mortimer M Civan, Nirupa Chaudhari, Ichiro Matsumoto, Göran Hellekant, Michael G Tordoff, Philippe Marambaud, J Kevin Foskett CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes. Nature: 2013, 495(7440);223-6 PubMed 23467090 | Nature
- Marika Kapsimali, Linda A Barlow Developing a sense of taste. Semin. Cell Dev. Biol.: 2013, 24(3);200-9 PubMed 23182899
- Camille I Petersen, Andrew H Jheon, Pasha Mostowfi, Cyril Charles, Saunders Ching, Shoba Thirumangalathu, Linda A Barlow, Ophir D Klein FGF signaling regulates the number of posterior taste papillae by controlling progenitor field size. PLoS Genet.: 2011, 7(6);e1002098 PubMed 21655085 | PMC3107195 | http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1002098 PLoS Genetics]
- Shoba Thirumangalathu, Danielle E Harlow, Amanda L Driskell, Robin F Krimm, Linda A Barlow Fate mapping of mammalian embryonic taste bud progenitors. Development: 2009, 136(9);1519-28 PubMed 19363153
- M Witt, K Reutter Embryonic and early fetal development of human taste buds: a transmission electron microscopical study. Anat. Rec.: 1996, 246(4);507-23 PubMed 8955790
- Danielle E Harlow, Linda A Barlow Embryonic origin of gustatory cranial sensory neurons. Dev. Biol.: 2007, 310(2);317-28 PubMed 17826760
- Ralf Kist, Michelle Watson, Moira Crosier, Max Robinson, Jennifer Fuchs, Julia Reichelt, Heiko Peters The formation of endoderm-derived taste sensory organs requires a pax9-dependent expansion of embryonic taste bud progenitor cells. PLoS Genet.: 2014, 10(10);e1004709 PubMed 25299669 | PLoS Genet.
Paloma Rohlfs Domínguez The study of postnatal and later development of the taste and olfactory systems using the human brain mapping approach: an update. Brain Res. Bull.: 2011, 84(2);118-24 PubMed 21184814
Nirupa Chaudhari, Stephen D Roper The cell biology of taste. J. Cell Biol.: 2010, 190(3);285-96 PubMed 20696704
Search May 2010
- Taste System Development - All (320) Review (64) Free Full Text (78)
- Tongue Development - All (2804) Review (258) Free Full Text (519)
- Tongue Images: Tongue Sk Muscle | Salivary gland sk muscle HE | Unlabeled Salivary gland sk muscle HE | Filiform papillae HE | circumvallate papilla VG | circumvallate papilla HE | Taste buds VG
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Cite this page: Hill, M.A. (2018, February 20) Embryology Sensory - Taste Development. Retrieved from https://embryology.med.unsw.edu.au/embryology/index.php/Sensory_-_Taste_Development
- © Dr Mark Hill 2018, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No. 00098G