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PMID 26166637
PMID 26166637
The objective of this investigations was to evaluate whether or not the pre-treatment use of Recombinant Human Follicle Stimulating Hormone (r-hFSH), could be used to treat common male infertility issues as  Idiopathic Oligozoospermia, to improve their clinical results of Intracytoplasmic Sperm Injection (ICSI).
They selected  a sample of 82 couples that were infertile due to the Idiopathic male factor, from the Biofertility Center in Rome, Italy between May 2013- April 2014 and randomly selected a treatment group  of 36 males, Group A, and control group of 46 men, Group. The men in treatment Group A were subcutaneously injected with  150 IU of R-hFSH; Gonad  F© (recombinant Human FSH)  3 times per week, for a  3 month period.  The subjects in the control Group B were injected with a placebo and therefore received no treatment.  After the three month period all 82 couples underwent a cycle of ICSI.
They found that the rate fertilisation was comparable in both treatment groups, although treatment group A had a significantly higher implantation rate and clinical pregnancy rate as well as a statistically significant lower rate of miscarriage (P<0.05). The conclusion that they drew was that the treatment use of r-hFSH to treat Idiopathic males infertility prior  to ICSI  can improve the clinical rate of pregnancy, increase the rate of implantation and decrease the chances of early pregnancy loss.





Revision as of 14:24, 13 August 2015

--Mark Hill (talk) 10:47, 6 August 2015 (AEST) Thanks for setting up your page. We will be talking more about this in the Practical on Friday.

Lab 1 Assessment

Your Lab assessment now requires you to find a 2 recent research references on fertilisation or in vitro fertilisation.

Paste each reference on your page, as shown in the class.

Write below each reference a brief summary of the research article methods and findings.

The summary for each need not be more than 3-4 paragraphs in length.

This will need to be completed before next weeks laboratory.

The use of r-hFSH in treatment of idiopathic male factor infertility before ICSI.

look at this [1]

PMID 26166637

The objective of this investigations was to evaluate whether or not the pre-treatment use of Recombinant Human Follicle Stimulating Hormone (r-hFSH), could be used to treat common male infertility issues as Idiopathic Oligozoospermia, to improve their clinical results of Intracytoplasmic Sperm Injection (ICSI). They selected a sample of 82 couples that were infertile due to the Idiopathic male factor, from the Biofertility Center in Rome, Italy between May 2013- April 2014 and randomly selected a treatment group of 36 males, Group A, and control group of 46 men, Group. The men in treatment Group A were subcutaneously injected with 150 IU of R-hFSH; Gonad F© (recombinant Human FSH) 3 times per week, for a 3 month period. The subjects in the control Group B were injected with a placebo and therefore received no treatment. After the three month period all 82 couples underwent a cycle of ICSI. They found that the rate fertilisation was comparable in both treatment groups, although treatment group A had a significantly higher implantation rate and clinical pregnancy rate as well as a statistically significant lower rate of miscarriage (P<0.05). The conclusion that they drew was that the treatment use of r-hFSH to treat Idiopathic males infertility prior to ICSI can improve the clinical rate of pregnancy, increase the rate of implantation and decrease the chances of early pregnancy loss.


Luteal phase ovarian stimulation following oocyte retrieval: is it helpful for poor responders?

look at this [2]

PMID 26209449


Lab Attendance

--Z5020317 (talk) 13:46, 7 August 2015 (AEST)

Test student 2015

References

--Mark Hill (talk) 10:21, 13 August 2015 (AEST) I have put the correct code for the reference list below.


  1. <pubmed>26166637</pubmed>
  2. <pubmed>26209449</pubmed>


Please do not use your real name on this website, use only your student number.

2015 Course: Week 2 Lecture 1 Lecture 2 Lab 1 | Week 3 Lecture 3 Lecture 4 Lab 2 | Week 4 Lecture 5 Lecture 6 Lab 3 | Week 5 Lecture 7 Lecture 8 Lab 4 | Week 6 Lecture 9 Lecture 10 Lab 5 | Week 7 Lecture 11 Lecture 12 Lab 6 | Week 8 Lecture 13 Lecture 14 Lab 7 | Week 9 Lecture 15 Lecture 16 Lab 8 | Week 10 Lecture 17 Lecture 18 Lab 9 | Week 11 Lecture 19 Lecture 20 Lab 10 | Week 12 Lecture 21 Lecture 22 Lab 11 | Week 13 Lecture 23 Lecture 24 Lab 12 | 2015 Projects: Three Person Embryos | Ovarian Hyper-stimulation Syndrome | Polycystic Ovarian Syndrome | Male Infertility | Oncofertility | Preimplantation Genetic Diagnosis | Students | Student Designed Quiz Questions | Moodle page

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