User:Z3463890
Lab Attendance
--Z3463890 (talk) 13:46, 7 August 2015 (AEST)
Lab Assessment 1
Article 1
"Effect of vitamin D status on clinical pregnancy rates following in vitro fertilization" [1] PMID 25077107
Summary
According to this study, vitamin D may play a role in human reproduction. Therefore, the aim of this study was to find out whether there is a correlation between vitamin D levels and implantation and clinical pregnancy rates in infertile women following IVF.
Method
• Total of 173 infertile women participated in the study that met the following criteria: aged 18-41 years, follicle stimulating hormone level 12 IU/L or lower and able to provide informed consent.
• 25(OH)D samples were collected within 1 week before oocyte retrieval from those infertile women.
• Vitamin D status was evaluated and determined by serum 25-hydroxy-vitamin D (25[OH]D) levels.
• Patients were classified in two different groups; having sufficient (≥ 75 nmol/L) or insufficient (or deficient; hereafter referred to as “insufficient”; < 75 nmol/L) serum levels of 25(OH)D.
• Patient demographics and IVF cycle parameters between two groups were compared.
• Clinical pregnancy, as identified by ultrasound following 4-5 weeks after embryo transfer; was the primary outcome measurement.
Findings
According to the outcome of this study, the women with sufficient levels of 25(OH)D had significantly higher rates of clinical pregnancy (52.5%) per IVF cycle started than that with insufficient levels (34.7%). Therefore, Vitamin D supplementation can potentially provide an easy and cost-effective way of improving pregnancy rates but requires further investigations as the results are not statistically significant in the sufficient 25(OH)D group.
Article 2
Examining the temperature of embryo culture in in vitro fertilization: a randomized controlled trial comparing traditional core temperature (37°C) to a more physiologic, cooler temperature (36°C). [2] PMID 25044079
References
References
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