User:Z3459224

Lab Attendance

--Z3459224 (talk) 13:46, 7 August 2015 (AEST)

Test student 2015

Lab Assessment 1

Article 1

PMID 25197669

Summary

Poor response to controlled ovarian hyperstimulation (COH) is still a major problem in IVF. Many protocols have been tested yet the results always show a poor outcome. Poor ovarian responders (PORs) exhibit reduced levels of oocyte quantity and may also exhibit a compromised oocyte quality due to the high risk in failing to implant.

This article proposes a novel treatment in the form of a luteinizing hormone (LH) pretreatment with the aim of using its ability as an androgen modulating agent to increase androgen accumulation in pre-antral and small antral follicles.

The study consisted of two sections. The first section included a randomised controlled trial with 43 young women who had a poor response to ovarian stimulation in at least two previous cycles. These patients were randomly allocated to 2 groups. Group A was the control group which received FSH stimulation while Group B received pretreatment with LH followed by the administration of FSH to fulfill the agonist downregulation protocol. The second section of the study entailed a treatment of 65 patients with the new protocol and then a comparison of these results to those from previous cycles.

The study's results indicated that LH pretreatment was successfully able to reduce cancellations in both the RCT and historical control study groups. The new protocol was also seen to have improved the oocyte's performance in vitro nd also increased the live birth rate.

Article 2

PMID 24760136

Reference

Please do not use your real name on this website, use only your student number.

2015 Course: Week 2 Lecture 1 Lecture 2 Lab 1 | Week 3 Lecture 3 Lecture 4 Lab 2 | Week 4 Lecture 5 Lecture 6 Lab 3 | Week 5 Lecture 7 Lecture 8 Lab 4 | Week 6 Lecture 9 Lecture 10 Lab 5 | Week 7 Lecture 11 Lecture 12 Lab 6 | Week 8 Lecture 13 Lecture 14 Lab 7 | Week 9 Lecture 15 Lecture 16 Lab 8 | Week 10 Lecture 17 Lecture 18 Lab 9 | Week 11 Lecture 19 Lecture 20 Lab 10 | Week 12 Lecture 21 Lecture 22 Lab 11 | Week 13 Lecture 23 Lecture 24 Lab 12 | 2015 Projects: Three Person Embryos | Ovarian Hyper-stimulation Syndrome | Polycystic Ovarian Syndrome | Male Infertility | Oncofertility | Preimplantation Genetic Diagnosis | Students | Student Designed Quiz Questions | Moodle page

Glossary Links

Glossary: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers | Symbols | Term Link