Talk:BGDA Lecture - Development of the Nervous System: Difference between revisions
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[[File:Stage10_neural_sm.jpg|thumb|300px|Neural groove closing to neural tube, early week 4 <br>([[Carnegie_stage_10|Stage 10]])]] | [[File:Stage10_neural_sm.jpg|thumb|300px|Neural groove closing to neural tube, early week 4 <br>([[Carnegie_stage_10|Stage 10]])]] | ||
[[File:Human brain growth 01.jpg|thumb|300px|alt=Brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)|Relative brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)]] | [[File:Human brain growth 01.jpg|thumb|300px|alt=Brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)|Relative brain size embryonic (week 4, 5, 6, and 8) and late fetal (third trimester)]] | ||
===Neuropores=== | |||
{| | |||
|- | |||
! Cranial Neuropore | |||
! Caudal Neuropore | |||
|- | |||
| [[File:Stage11 sem9.jpg|200px]] | |||
| [[File:Stage12_SEM3.jpg|200px]] | |||
|- | |||
| ([[Carnegie stage 11|stage 11]]) | |||
| ([[Carnegie stage 12|stage 12]]) | |||
|} | |||
* cranial (anterior) neuropore closes before caudal (posterior) | |||
* failure to close - Neural Tube Defects (NTD), severity dependent upon level, spina bifida anancephaly (More? [neuron2.htm Neural Abnormalities]) | |||
* found that supplementation of maternal diet with folate reduces incidence of NTDs | |||
** A randomised controlled trial conducted by the Medical Research Council of the United Kingdom demonstrated a 72% reduction in risk of recurrence by periconceptional (ie before and after conception) folic acid supplementation (4mg daily). | |||
** Women who have one infant with a neural tube defect have a significantly increased risk of recurrence (40-50 per thousand compared with 2 per thousand for all births) | |||
Revision as of 15:54, 18 May 2017
2017
Monday 29 May 2017 09:00 AM - 10:00 AM Development of the nervous system Kensington - Rex Vowels Theatre Hill, Mark
Neuropores
Cranial Neuropore | Caudal Neuropore |
---|---|
(stage 11) | (stage 12) |
- cranial (anterior) neuropore closes before caudal (posterior)
- failure to close - Neural Tube Defects (NTD), severity dependent upon level, spina bifida anancephaly (More? [neuron2.htm Neural Abnormalities])
- found that supplementation of maternal diet with folate reduces incidence of NTDs
- A randomised controlled trial conducted by the Medical Research Council of the United Kingdom demonstrated a 72% reduction in risk of recurrence by periconceptional (ie before and after conception) folic acid supplementation (4mg daily).
- Women who have one infant with a neural tube defect have a significantly increased risk of recurrence (40-50 per thousand compared with 2 per thousand for all births)